Heterotypic 3D Model of Breast Cancer Based on Tumor, Stromal and Endothelial Cells: Cytokines Interaction in the Tumor Microenvironment [PDF]
The recreation of the tumor microenvironment remains a significant challenge in the development of experimental cancer models. The present study constitutes an investigation into the interconnection between tumor, endothelial and stromal cells in ...
Anastasia Leonteva +10 more
doaj +2 more sources
Spheroidal ambisonics: Spatial audio in spheroidal bases [PDF]
Ambisonics is an established framework to capture and reproduce spatial sound fields based on the spherical harmonics representation [Gerzon (1973). J. Audio Eng. Soc. 21(1), 2–10]. A generalization—spheroidal ambisonics—based on spheroidal wave functions is proposed for use with spheroidal microphone arrays.
Shoken, Kaneko, Ramani, Duraiswami
openaire +2 more sources
Evaluation of the Properties and Osteogenic Potential of a Novel Scaffold-Free Material, Spheroid Blocks Comprising Fused Spheroids of Human Periodontal Ligament Mesenchymal Stem Cells [PDF]
Periodontal ligament stem cell spheroids are reportedly valuable for tissue regeneration; however, their application in vivo requires the use of a scaffold, which may raise safety concerns.
Kotaro Sano +9 more
doaj +2 more sources
Human brain organoids in Alzheimer’s disease [PDF]
Alzheimer’s disease (AD) is a progressive neurological disorder that typically involves neuronal damage leading to the deterioration of cognitive and essential body functions in aging brains.
You Jung Kang, Hansang Cho
doaj +1 more source
COORDINATE TRANSFORMATION FROM KARBALA 1979 AND WORLD GEODETIC SYSTEM 1984 TO IRAQI GEOSPATIAL REFERENCE SYSTEM [PDF]
Nowadays, the transformation between coordinate systems is the major interested problems especially in Iraq. There are many coordinate systems used to produce maps and documentations due to different datums and spheroids.
Ruba Y. Hussain
doaj +1 more source
Gravity-Based Flow Efficient Perfusion Culture System for Spheroids Mimicking Liver Inflammation
The spheroid culture system provides an efficient method to emulate organ-specific pathophysiology, overcoming the traditional two-dimensional (2D) cell culture limitations.
Young-Su Kim +5 more
doaj +1 more source
O2-sensitive microcavity arrays: A new platform for oxygen measurements in 3D cell cultures
Oxygen concentration plays a crucial role in (3D) cell culture. However, the oxygen content in vitro is usually not comparable to the in vivo situation, which is partly due to the fact that most experiments are performed under ambient atmosphere ...
Christoph Grün +3 more
doaj +1 more source
Advanced spheroidal degeneration [PDF]
Spheroidal degeneration, involving the cornea and/or the conjunctiva, is characterized by amber-colored homogeneous, translucent spherules in the corneal stroma, Bowman’s membrane, and subepithelium. The condition has a higher prevalence in areas with extreme temperatures, low humidity, high wind, and presence of sand.
Abdelrahman M, Elhusseiny +5 more
openaire +2 more sources
Compared with traditional two-dimensional culture, a three-dimensional (3D) culture platform can not only provide more reliable prediction results, but also provide a simple, inexpensive and less time-consuming method compared with animal models.
Siwei Ding +5 more
doaj +1 more source
Spheroids are recognized for resembling the important characteristics of natural tumors in cancer research. However, the lack of controllability of the spheroid size, form, and density in conventional spheroid culture methods reduces the reproducibility ...
Neda Azizipour +5 more
doaj +1 more source

