Results 41 to 50 of about 117,630 (212)
Biomolecules, 2019 The aim of this study was to investigate the potential anti-cancer effects of probiotic cell-free supernatant (CFS) treatment using Lactobacillus fermentum for colorectal cancer (CRC) in 3D culture systems.
Joo-Eun Lee +9 more
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Scientific Reports, 2016 The potential of a spheroid tumor model composed of cells in different proliferative and metabolic states for the development of new anticancer strategies has been amply demonstrated.
M. Zanoni +7 more
semanticscholar +1 more source
Engineering three-dimensional bone macro-tissues by guided fusion of cell spheroids
Frontiers in Endocrinology, 2023 IntroductionBioassembly techniques for the application of scaffold-free tissue engineering approaches have evolved in recent years toward producing larger tissue equivalents that structurally and functionally mimic native tissues.
Vinothini Prabhakaran +8 more
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Dwarf Spheroidal Galaxies [PDF]
Symposium - International Astronomical Union, 1994 Dwarf Spheroidal (dSph) galaxies are the faintest baryonic systems recognized as galaxies. Understanding the structure and stellar populations of these systems is critical for the modelling of their formation and evolution, and by extension, for understanding the general problem of galaxy formation ...
openaire +1 more source
Biomaterials, 2019 Tumor vasculature creates a hostile tumor microenvironment (TME) in vivo and nourishes cancers, resulting in cancer progression and drug resistance. To mimic the biochemical and biomechanical environments of tumors in vitro, several models integrated ...
Yuji Nashimoto +6 more
semanticscholar +1 more source
Evaluation of Nanoparticle Penetration in the Tumor Spheroid Using Two-Photon Microscopy
Biomedicines, 2020 Mesoporous silica nanoparticles (MSNs) have emerged as a prominent nanomedicine platform, especially for tumor-related nanocarrier systems. However, there is increasing concern about the ability of nanoparticles (NPs) to penetrate solid tumors, resulting
Feby Wijaya Pratiwi +6 more
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Biofidelic dynamic compression of human cortical spheroids reproduces neurotrauma phenotypes
Disease Models & Mechanisms, 2021 Fundamental questions about patient heterogeneity and human-specific pathophysiology currently obstruct progress towards a therapy for traumatic brain injury (TBI). Human in vitro models have the potential to address these questions.
Aaron R. Shoemaker +9 more
doaj +1 more source
Applied Sciences, 2018 Mesenchymal stem cells (MSCs) reside quiescently within a specialised ‘niche’ environment in the bone marrow. However, following appropriate signalling cues, MSCs mobilise and migrate out from the niche, typically toward either sites of injury (a ...
Jake Casson +4 more
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Collagen Partition in Polymeric Aqueous Two-Phase Systems for Tissue Engineering
Frontiers in Chemistry, 2018 Aqueous two-phase systems (ATPS) of polyethylene glycol (PEG) and dextran (DEX) are commonly used to partition proteins. Protein partition in ATPS is a complex phenomenon and depends on factors including molecular weight of polymers, and electrochemical ...
Sunil Singh, Hossein Tavana
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Frontiers in Bioengineering and BiotechnologyIntroductionSpheroids are promising building blocks for scaffold-free bone tissue engineering. Their rapid vascularization is of major importance to guarantee their survival after transplantation.
Selina Wrublewsky +9 more
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