Results 61 to 70 of about 60,705 (304)
PharmaceuticalsBackground: Endometrial cancer remains a significant health concern, with type 1 endometrial cancer characterized by aberrant expression of estrogen-dependent and mTOR pathway proteins.
Muhammet Volkan Bulbul +7 more
doaj +1 more source
Dwarf spheroidals in MOND [PDF]
Monthly Notices of the Royal Astronomical Society, 2008 We take the line of sight velocity dispersions as functions of radius for 8 Milky Way dwarf spheroidal galaxies and use Jeans analysis to calculate the mass-to-light ratios (M/L) in Modified Newtonian Dynamics (MOND). Using the latest structural parameters, distances and variable velocity anisotropy, we find 6/8 dwarfs have sensible M/L using only the ...
openaire +2 more sources
Spheroidal Ambisonics: a Spatial Audio Framework Using Spheroidal Bases
CoRR, 2021 Ambisonics is an established framework to capture, process, and reproduce spatial sound fields based on its spherical harmonics representation. We propose a generalization of conventional spherical ambisonics to the spheroidal coordinate system and spheroidal microphone arrays, which represent sound fields by means of spheroidal wave functions.
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Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Frontiers in Veterinary ScienceIntroductionMesenchymal stem cells (MSCs) have been introduced as a treatment for dogs owing to their immunomodulatory effects. In humans, 3D-cultured MSCs have recently been applied in treating various conditions, including myocardial infarction, liver ...
Eunbi Lee +6 more
doaj +1 more source
Pharmaceutics, 2019 The efficiency of delivering a therapeutic agent into a tumor is among the crucial factors determining the prospects for its clinical use. This problem is particularly acute in the case of targeted antitumor agents since many of them are high-molecular ...
Evgeniya Sokolova +7 more
doaj +1 more source
Development of a stem cell spheroid‐laden patch with high retention at skin wound site
Bioengineering & Translational Medicine, 2022 Mesenchymal stem cells such as human adipose tissue‐derived stem cells (hADSCs) have been used as a representative therapeutic agent for tissue regeneration because of their high proliferation and paracrine factor‐secreting abilities.
Gun‐Jae Jeong +11 more
doaj +1 more source
Dwarf Spheroidal Galaxies [PDF]
Symposium - International Astronomical Union, 1994 Dwarf Spheroidal (dSph) galaxies are the faintest baryonic systems recognized as galaxies. Understanding the structure and stellar populations of these systems is critical for the modelling of their formation and evolution, and by extension, for understanding the general problem of galaxy formation ...
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Immunostaining of invading spheroid.
, 2022 a) Spheroid fixed after 3 days in an aligned collagen gel in a microfluidic channel. The images show brightfield (BF), YAP immuno-staining (YAP, yellow), the nuclei stained with Hoechst 33342 (cell nuclei, blue), and a composite of YAP and Hoechst.
Manuel S. Brugger (12174360) +4 more
core +1 more source
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source