Results 201 to 210 of about 9,343 (242)

The serine palmitoyl transferase of plant pathogenic fungi: a promising new target for the development of novel crop protection solutions^†. [PDF]

Pest Manag Sci
Nicolas L, Hilz E, Gamet S, Thomas V, Peyrard S, Di Vietro L, Cirer B, Geist J, Essigmann B, Ferry A, Chanel A, Berniaud F, Schwarz D, Lempereur V.   +13 more
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Metabolomics insights into doxorubicin and 5-fluorouracil combination therapy in triple-negative breast cancer: a xenograft mouse model study. [PDF]

Front Mol Biosci
Hassanein MM, Hagyousif YA, Zenati RA, Al-Hroub HM, Khan FM, Abuhelwa AY, Alzoubi KH, Soares NC, El-Huneidi W, Abu-Gharbieh E, Omar H, Zaher DM, Bustanji Y, Semreen MH.   +13 more
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The enzymatic phosphorylation of sphinganine

Biochemical and Biophysical Research Communications, 1969
Abstract A partially purified enzyme preparation from bovine kidney has been shown to catalyze the phosphorylation of sphinganine. The enzyme utilizes ATP as a phosphate donor and the product of the reaction has been identified as sphinganine-1-phosphate.
R W, Keenan, B, Haegelin
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Approaches to the preparation of sphinganines

Tetrahedron, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Amy R. Howell, Regina C. So, Stewart K. Richardson   +2 more
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Inhibition of microbial adherence by sphinganine

Canadian Journal of Microbiology, 1992
Sphingosines (precursors and degeneration products of complex sphingolipids) are mediators in membrane second-messenger cascades and in a wide variety of functions in eukaryotic cells. Sphingosines are also lethal for gram-positive microorganisms. In addition to its direct effect, sphinganine is here reported to affect the adherence of Streptococcus ...
D J, Bibel, R, Aly, H R, Shinefield
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Synthesis of threo-4,5-dihydroxy diastereomers of sphinganine

Chemistry and Physics of Lipids, 1975
The threo-4,5-dihydroxy diastereomers of sphinganine were prepared by the following sequence of reactions: (a) benzoylation of sphingenine to the tribenzoyl derivative; (b) osmylation followed by resolution of the mixture of threo-4,5-dihydroxy tribenzoyl (DHTBS) diastereomers; and (c) alkaline hydrolysis to yield the threo-4,5-dihydroxysphinganines ...
B, Weiss, R L, Stiller
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Effects of fumonisins on liver and kidney sphinganine and the sphinganine to sphingosine ratio during chronic exposure in ducks

Chemico-Biological Interactions, 2006
Sa and the Sa/So ratio are very sensitive biomarkers of exposure to fumonisins in several species. We previously demonstrated that increases in Sa and in the Sa/So ratio in serum were less pronounced when ducks ingested fumonisins for more than 7 weeks than when animals were exposed for only 1-2 weeks [S.T. Tran, D. Tardieu, A. Auvergne, J.D. Bailly, R.
Tardieu, Delphine, Tran, Stéphane, Auvergne, Alain, Babile, René, Bénard, G., Bailly, J.D., Guerre, P.   +6 more
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Serum sphinganine and the sphinganine to sphingosine ratio as a biomarker of dietary fumonisins during chronic exposure in ducks

Chemico-Biological Interactions, 2006
Sphinganine concentration (Sa) and sphinganine to sphingosine ratio (Sa/So) are sensitive biomarkers of fumonisin B1 (FB1) exposure in animals and have been proposed to reveal FB1 exposure in humans. They correlate with liver and kidney toxicity and often precede signs of toxicity.
Tran, Stéphane, Tardieu, Delphine, Auvergne, Alain, Bailly, J.D., Babile, René, Durand, S., Bénard, G., Guerre, P.   +7 more
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Tissue sphinganine as a biomarker of fumonisin-induced apoptosis

Food Additives and Contaminants, 2001
NCTR measured sphinganine concentrations in the livers of mice and in the livers and kidneys of rats in conjunction with a tumour bioassay. In our model of the tumour incidence, target-tissue levels of sphinganine serve as a biomarker for a dose response of fumonisin B1 on cell death.
R R, Delongchamp, J F, Young
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