Results 251 to 260 of about 48,095 (292)

The Phospholipid Bis(monoacylglycero)Phosphate Confers Antitumour Immunogenicity to Exosomes Secreted by Dendrogenin A, Which Activates Its Biosynthesis in Tumour Cells

Journal of Extracellular Vesicles, Volume 15, Issue 2, February 2026.
Dendrogenin A stimulates, via LXRβ, the expression and activity of enzymes responsible for the biosynthesis of the phospholipid BMP. BMP is a key determinant of the antitumour immunogenicity of exosomes secreted by DDA‐treated melanoma and triple‐negative breast cancer cells and enhances mouse survival and anti‐PD‐1 therapy in melanoma.
Julio Buñay, Michel Record, Philippe de Medina, Silia Ayadi, Laly Pucheu, Céline Colacios, Bruno Ségui, Marcus Höring, Gerhard Liebisch, Hélène Martin, Marc Poirot, Sandrine Silvente‐Poirot   +11 more
wiley   +1 more source

A career in bioactive lipids. [PDF]

J Biol Chem
Hannun YA.
europepmc   +1 more source

Comparative lipidomic and proteomic analysis reveals species‐specific differences in midgut composition and insecticide absorption between Apis mellifera and Bombus terrestris

Pest Management Science, Volume 82, Issue 2, Page 1540-1551, February 2026.
Lipidomic and proteomic analysis revealed large‐scale differences in the midgut composition of the honeybee Apis mellifera and the buff‐tailed bumblebee Bombus terrestris. These differences correlated to increased insecticide absorption in the bumblebee when using an ex vivo Ussing chamber and subsequently in vivo feeding assay (created in Biorender ...
Emmanouil Kokkas, Joseph Hawkins, Lauraine Swindale, Aniko Kende, John Sinclair, Jacob M Riveron, Helen Thompson, Adam Pym   +7 more
wiley   +1 more source

Inhibition of PFKFB3 in Macrophages Has a Dual Effect on Tumor-Regulating Lipid Metabolism. [PDF]

Int J Mol Sci
Shmakova E, Sudarskikh T, Shalygina K, Chagovets V, Starodubtseva N, Tokareva A, Novoselova A, Frankevich V, Tarasova A, Kostromitsky D, Dobrodeev A, Afanas'ev S, Larionova I, Kzhyshkowska J.   +13 more
europepmc   +1 more source

Lifespan‐Extending Endogenous Metabolites

Aging Cell, Volume 25, Issue 2, February 2026.
Endogenous metabolites act as mediators of longevity by modulating conserved cellular pathways. We summarize mechanistic evidence linking specific metabolites to lifespan and healthspan benefits across model systems, with discussion of clinical evidence, translational opportunities, and remaining knowledge gaps.
Yizhou Jiang, Jing‐Dong J. Han
wiley   +1 more source

Lipidomic Profiling of Red Blood Cells in the Mitochondrial Fatty Acid β-oxidation Disorder MCADD Reveals Phospholipid and Sphingolipid Dysregulation

Inês M. S. Guerra, Helena Beatriz Ferreira, Luísa Diogo, Sónia Moreira, Stefano Bonciarelli, Laura Goracci, Tânia Melo, Pedro Domíngues, M. Rosário Domingues, Ana S. P. Moreira   +9 more
openalex   +1 more source

Molecular Maestro in the Lung: The Sphingolipid Rheostat. [PDF]

Am J Respir Cell Mol Biol
Rojas-Quintero J, Polverino F.
europepmc   +1 more source

Intestinal bacteria trigger a hibernation-like state in homotherms via the gut-brain axis. [PDF]

NPJ Biofilms Microbiomes
Bao Z, Guo C, Chen Y, Lei T, Peng H, Zhang H, Zhang X, Ban Y, Qi D, Feng J, Xiang Z.   +10 more
europepmc   +1 more source

Gut bacteria-derived sphingolipids alter innate immune responses to oral cholera vaccine antigens. [PDF]

Nat Commun
Chac D, Heller FJ, Banna HA, Kaisar MH, Markiewicz SM, Pruitt EL, Chowdhury F, Bhuiyan TR, Akter A, Khan AI, Dumayas MG, Rice A, Karmakar PC, Dash P, LaRocque RC, Ryan ET, Xu L, Minot SS, Harris JB, Qadri F, Weil AA.   +20 more
europepmc   +1 more source

The Involvement of Ceramide, Sphingosine-1-Phosphate and Ganglioside GM1 in Regulating Some Nervous System Functions. [PDF]

Int J Mol Sci
Giussani P, Mauri L, Sonnino S.
europepmc   +1 more source