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2023
Sphingolipids are a class of lipids containing the backbone of long-chain amino-alcohol bases in their structure, which are synthesized in the endoplasmic reticulum. Modification of this base gives rise to a variety of such lipids ranging from simple to complex sphingolipids that play a significant structural and functional role in membrane biology as ...
Shaista Nosheen +3 more
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Sphingolipids are a class of lipids containing the backbone of long-chain amino-alcohol bases in their structure, which are synthesized in the endoplasmic reticulum. Modification of this base gives rise to a variety of such lipids ranging from simple to complex sphingolipids that play a significant structural and functional role in membrane biology as ...
Shaista Nosheen +3 more
openaire +1 more source
Functions of Sphingolipids and Sphingolipid Breakdown Products in Cellular Regulation
Science, 1989The discovery that breakdown products of cellular sphingolipids are biologically active has generated interest in the role of these molecules in cell physiology and pathology. Sphingolipid breakdown products, sphingosine and lysosphingolipids, inhibit protein kinase C, a pivotal enzyme in cell regulation and signal transduction.
Y A, Hannun, R M, Bell
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Sphingolipids in inflammatory hypoxia
Biological Chemistry, 2018Abstract Hypoxia due to rapid tumor growth with impaired neovascularization and inflammation resulting from immune cell activation are hallmarks of cancer. Hypoxia-inducible factors control transcriptional adaptation in response to low oxygen conditions, both in tumor and immune cells.
Glaser, Ulrike G, Fandrey, Joachim
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Increasing Sphingolipid Synthesis Alleviates Airway Hyperreactivity
American Journal of Respiratory Cell and Molecular Biology, 2020Arul Veerappan +2 more
exaly
Emerging Roles of Sphingolipid Signaling in Plant Response to Biotic and Abiotic Stresses
Molecular Plant, 2018Usman Ali, Xuemin Wang, Liang Guo
exaly
Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids, 2006
Yusuf A Hannun, Y A Hannun
exaly
Yusuf A Hannun, Y A Hannun
exaly

