Results 181 to 190 of about 908,827 (288)

Established and Emerging Biomarkers to Characterize Persons at Risk for Obesity—Paving the Way for Targeted Clinical Intervention Trials—A Comprehensive Position Paper

Obesity Reviews, EarlyView.
ABSTRACT Despite all efforts, obesity remains a major health concern worldwide, with continuously increasing rates, affecting approx. 14% of the total world population, being as high as 43% in some countries. As obesity is related to numerous comorbidities, including type 2 diabetes, cardiovascular diseases, and some types of cancer, the consequences ...
Farhad Vahid, Victoria Stopa, Laurent Malisoux, Yvan Devaux, Elsa Lamy, Fernando Capela e Silva, Sarah Forberger, Tiziana de Magistris, Antoni Sureda, Margalida Monserrat‐Mesquida, Maria Pérez‐Jiménez, Rajini Nagrani, Maria Giovanna Onorati, Michele Filippo Fontefrancesco, Jonathan Turner, Mahesh S. Desai, Josep Tur, Cristina Bouzas, Gino Gabriel Bonetti, Oliver Riedel, Gitte Ravn‐Haren, Rikke Andersen, Torsten Bohn   +22 more
wiley   +1 more source

Myostatin Inhibitory D‑Peptides Induce Skeletal Muscle Hypertrophy along with Alteration of Bioactive Sphingolipid Metabolism. [PDF]

ACS Pharmacol Transl Sci
Morito K, Nishikawa N, Hitachi K, Tamaki R, Nishikawa M, Hayashi Y, Tsuchida K, Takayama K.   +7 more
europepmc   +1 more source

Investigating Overweight and Obesity Risk in Shift Workers Using Omics Technologies

Obesity Reviews, EarlyView.
ABSTRACT Night shift workers are at higher risk of developing overweight and obesity. The disruption of the physiological circadian rhythm leads to metabolic alterations, such as decreased insulin sensitivity, increased adipogenesis, and inflammation, with effects on their health and leading, among other diseases, to obesity.
Katrin Scionti, Ivana Václavková, Vanessa Schoissengeier, Karl‐Heinz Wagner   +3 more
wiley   +1 more source

Altered Sphingolipid Metabolism is Associated with Osimertinib Resistance in Nonsmall-Cell Lung Cancer. [PDF]

J Proteome Res
Babuta J, Gruevska A, Wickremesinghe C, Montoya A, Roumelioti G, Shliaha P, Balcells C, McKinney F, Bray C, Athersuch T, Martin M, Keun H, Hall Z.   +12 more
europepmc   +1 more source

Unexpected Suppression of Tomato Fruit Cuticle Formation by Overexpression of a Key Cutin Biosynthetic Enzyme

Plant Biotechnology Journal, EarlyView.
ABSTRACT Fruit cuticles regulate the diffusion of water, gases and solutes, functioning as essential protective interfaces against environmental and biotic stresses. Engineering cuticle structure and mechanics therefore represents a promising strategy for improving fruit quality and resilience.
Gulab Chand Arya, Ekram Wassel, Vibha Mishra, Ekaterina Manasherova, Ruth E. Stark, Hagai Cohen   +5 more
wiley   +1 more source

Mediation of sphingolipid metabolism on the relationship between human nitrosamines exposure and esophageal cancer risk. [PDF]

Sci Rep
Zhao C, Xia Y, Shi Q, Gu Y, Zhang L, Dong R, Zhang Y, Han S, Jiang Y, Xiong W, Guo H, Wang B, Xia J, Wang Q, Zhang H, Bao Y.   +15 more
europepmc   +1 more source

Hidden Strategies Beneath a Single Nucleotide: Contrasting Physiology in Lichen Photobiont Strains

Plant, Cell &Environment, EarlyView.
ABSTRACT Lichen photobionts exhibit significant physiological variability with important ecological implications. While this variability is relatively well studied at the interspecific level, it has rarely been examined at the intraspecific level. Here, we investigated the physiological responses to temperature and irradiance of two Trebouxia lynniae ...
Miguel Blázquez, David Pizarro, Ana García‐Muñoz, Raquel Pino‐Bodas, Asunción de los Ríos, Miren I. Arzac, José Ignacio García‐Plazaola, Beatriz Fernández‐Marín, Unai Artetxe, Rosa Toledo‐Gil, Fernando Vallejo, Leonardo M. Casano, Israel Pérez‐Vargas, Sergio Pérez‐Ortega, Francisco Gasulla   +14 more
wiley   +1 more source

Integrated transcriptomic and tissue-validation analyses identify palmitoylation-associated biomarkers linked to sphingolipid metabolism and immune remodeling in psoriasis. [PDF]

Front Immunol
Luo Q, Shi R, Yang D, Tang Y, Xie Q, Shi Y, Sun F.   +6 more
europepmc   +1 more source

Understanding extracellular vesicle biology, isolation, and characterization: The theory of EV‐erything

Periodontology 2000, EarlyView.
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad, Nima Farshidfar, Nathan E. Estrin, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +6 more
wiley   +1 more source

<i>Porphyromonas gingivalis</i>-Derived Phosphoglycerol-isoC17:0-Dihydroceramide Reprograms Sphingolipid Metabolism in Human OECM-1 Oral Squamous Cell Carcinoma Cells. [PDF]

FASEB Bioadv
Yamada C, Ho A, Sanz N, Peng G, Xu R, Mao C, Yuan X, Momen-Heravi F, Edwards PC, Nichols F, Movila A.   +10 more
europepmc   +1 more source