Clinical and Translational Science, Volume 19, Issue 5, May 2026.ABSTRACT Reliable biomarkers that enable noninvasive, longitudinal assessment of disease activity and therapeutic response remain a major unmet need in inflammatory bowel disease (IBD). While colonic biopsies are the gold standard for evaluating mucosal inflammation, their invasive nature and limited spatial and temporal resolution constrain their ...
Mohamed Hassanein +8 more
wiley +1 more source
Editorial: The role of sphingolipid metabolism in endocrine diseases. [PDF]
Front Endocrinol (Lausanne)Li C, Li G.
europepmc +1 more source
The Secretome Derived From Serum‐Free Media of SHED‐MSCs Can Modulate THP‐1‐Derived Macrophage Cells
Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.ABSTRACT Although culturing cells in serum‐free or low‐serum media may lead to reduced cell proliferation, it is crucial to minimise the presence of foreign proteins and other impurities that could compromise the validity of experimental findings on immunomodulation.
Azadeh Mohammad‐Hasani +4 more
wiley +1 more source
Single-cell transcriptome sequencing reveals the sphingolipid metabolism pathway plays an important role in leaf senescence in tobacco. [PDF]
BMC Plant BiolSun Q +11 more
europepmc +1 more source
Journal of Clinical Periodontology, Volume 53, Issue 5, Page 774-783, May 2026.ABSTRACT Aim(s) This cross‐sectional clinical study aimed to explore the untargeted metabolomic and lipidomic profiles in gingival crevicular fluid (GCF) obtained from healthy individuals and patients with periodontitis. Materials and Methods GCF was collected from 17 periodontally healthy and 19 periodontitis patients.
Caroline H. Henderzahs +6 more
wiley +1 more source
Correction to "Chronic Cerebral Hypoperfusion Aggravates Parkinson's Disease Dementia-Like Symptoms and Pathology in 6-OHDA-Lesioned Rat through Interfering with Sphingolipid Metabolism". [PDF]
Oxid Med Cell Longeveuropepmc +1 more source
<i>Latilactobacillus sakei</i> CNTA 173 Reduces Fat Mass by Modulating Sphingolipid Metabolism in Diet-Induced Obese Wistar Rats. [PDF]
J Agric Food ChemGoyache I +8 more
europepmc +1 more source
Microcirculation, Volume 33, Issue 4, May 2026.ABSTRACT Objective Perivascular adipose tissue (PVAT) surrounds most peripheral blood vessels and exerts an anti‐contractile influence through paracrine mediators. Although numerous vasoactive factors have been identified, the mechanisms linking adipocyte metabolism to PVAT‐dependent modulation of vascular tone remain poorly defined. Because adipocytes
Miranda Hyatt +9 more
wiley +1 more source
Sphingolipid Metabolism and Signalling Pathways in Heart Failure: From Molecular Mechanism to Therapeutic Potential. [PDF]
J Inflamm ResZhao M +5 more
europepmc +1 more source
Serial Spatial Transcriptomes Reveal Regulatory Transitions in Maize Leaf Development
Plant Biotechnology Journal, Volume 24, Issue 5, Page 2787-2810, May 2026.ABSTRACT Plant leaves originate from the shoot apical meristem (SAM) and undergo a developmental process of highly coordinated gene expression regulation. To date, only a few key regulators have been identified and characterised, so the gene expression cascades responsible for leaf cell specification and differentiation from SAM remain largely elusive.
Chi‐Chih Wu +11 more
wiley +1 more source