Results 251 to 260 of about 35,165 (291)

Translational aspects of sphingolipid metabolism

Trends in Molecular Medicine, 2007
Sphingolipids, a major class of lipids in cell membranes, play diverse roles in biological processes. As bioactive and structural molecules, they have signaling activities and biophysical properties that are essential for regulating various cellular, tissue and systemic functions.
Youssef H, Zeidan, Yusuf A, Hannun
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Sphingolipid Metabolism and Metabolic Disease

Advances in Experimental Medicine and Biology, 2022
exaly   +2 more sources

Sphingolipid Metabolism in Tumor Cells

Biochemistry (Moscow), 2023
Sphingolipids are a diverse family of complex lipids typically composed of a sphingoid base bound to a fatty acid via amide bond. The metabolism of sphingolipids has long remained out of focus of biochemical studies. Recently, it has been attracting an increasing interest of researchers because of different and often multidirectional effects ...
Pokrovsky Vadim S., Ivanova-Radkevich Veronika I., Kuznetsova Olga M.   +2 more
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Sphingolipid Metabolism inBacteroideaceae

Hoppe-Seyler´s Zeitschrift für physiologische Chemie, 1975
The lipid composition of the anaerobic Bacteroides thetaiotaomikron has been analyzed. Sphingomyelin, ceramide phosphinicoethanolamine, free even-numbered and branched chain sphingosine bases and ceramide represented about 50% of the total lipid extract. The main ester phospholipid was phosphatidylethanolamine.
W, Stoffel, K, Dittmar, R, Wilmes
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Sphingolipid Metabolism and Atherosclerosis

2013
Atherosclerosis is the major cause of mortality in the developed countries. Although presently known risk factors have some predictive value for the disease, a major part of the variability in this process remains unexplained. It is extremely important to find new approaches for better understanding of the disease and for treating it.
Xian-Cheng, Jiang, Jing, Liu
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Sphingolipid Metabolism and Analysis in Metabolic Disease

2011
Sphingolipids are an important class of structural and signaling molecules within the cell. As sphingolipids have been implicated in the development and pathogenesis of insulin resistance and the metabolic syndrome, it is important to understand their regulation and metabolism.
Sarah E, Brice, L Ashley, Cowart
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The metabolism and function of sphingolipids and glycosphingolipids

Cellular and Molecular Life Sciences, 2007
Sphingolipids and glycosphingolipids are emerging as major players in many facets of cell physiology and pathophysiology. We now present an overview of sphingolipid biochemistry and physiology, followed by a brief presentation of recent advances in translational research related to sphingolipids. In discussing sphingolipid biochemistry, we focus on the
S, Lahiri, A H, Futerman
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Yeast sphingolipids: metabolism and biology

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2002
Sphingolipids have recently emerged as important bioactive molecules in addition to being critical structural components of cellular membranes. These molecules have been implicated in regulating cell growth, differentiation, angiogenesis, apoptosis, and senescene.
Lina M, Obeid, Yasuo, Okamoto, Cungui, Mao   +2 more
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Sphingolipid metabolism and drug resistance in ovarian cancer

Cancer Drug Resistance (Alhambra, Calif ), 2018
Despite progress in understanding molecular aberrations that contribute to the development and progression of ovarian cancer, virtually all patients succumb to drug resistant disease at relapse.
Robert C A M Van Waardenburg, Karina J Yoon   +1 more
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