Results 241 to 250 of about 35,165 (291)

Acute Lung Injury: From Molecular Circuits to System‐Level Therapeutics

open access: yesMedComm, Volume 7, Issue 6, June 2026.
This visual summary illustrates the paradigm shift from linear pathways to network medicine in ALI. Three interconnected circuits—innate immunity, immunometabolism, and cell death (PANoptosis)—drive disease progression under multiorgan crosstalk (gut–lung, brain–lung).
Yaoli Hou   +10 more
wiley   +1 more source

EMP1 safeguards hematopoietic stem cells by suppressing sphingolipid metabolism and alleviating endoplasmic reticulum stress. [PDF]

open access: yesNat Commun
Li L   +12 more
europepmc   +1 more source

Encephalopathy: Cause, Pathogenesis, and Treatment

open access: yesMedComm, Volume 7, Issue 6, June 2026.
Various encephalopathies (sepsis‐associated, hepatic, hypoxic–ischemic, diabetic, uremic, toxic) have incompletely elucidated pathogenesis, which severely restricts targeted therapy development. Small molecule drugs show unique multitarget potential but face toxicity, poor blood–brain barrier penetration and unclear specificity.
Shimeng Lv   +7 more
wiley   +1 more source

Alzheimer's disease manifests abnormal sphingolipid metabolism. [PDF]

open access: yesFront Aging Neurosci
Uranbileg B   +5 more
europepmc   +1 more source

Disturbing Cholesterol/Sphingolipid Metabolism by Squalene Epoxidase Arises Crizotinib Hepatotoxicity. [PDF]

open access: yesAdv Sci (Weinh)
Yan H   +14 more
europepmc   +1 more source

Poster Sessions

open access: yes
HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

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