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Chemotherapy and Sphingolipid Metabolism
2015It is well established that sphingolipids are crucial signal transducers regulating several cellular processes like growth, proliferation, response to stress, differentiation, senescence, autophagy and apoptosis. The critical role of sphingolipids in cancer initiation, progression, pathogenesis and metastasis has led to an expanding interest in ...
Ushma A. Doshi +4 more
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Disorders of Sphingolipid Metabolism
2006Sphingolipidoses are a subgroup of lysosomal storage disorders in which sphingolipids accumulate in one or several organs as the result of a primary deficiency in enzymes or activator proteins involved in their degradative pathway. Traditionally, this subgroup also includes Niemann-Pick disease type C, characterized by impaired cellular trafficking of ...
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Disorders of Sphingolipid Metabolism
2000Sphingolipidoses are a subgroup of lysosomal storage disorders. They are characterized by relentless progressive storage in affected organs and concomitant functional impairments. No overall screening procedure for these disorders is available. Their course and appearance, however, are usually characteristic and, together with relevant technical ...
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Sphingolipids and Metabolic Disease
2011Sphingolipid Metabolism and Analysis in Metabolic Disease.- Sphingolipids and Cardiovascular Diseases: Lipoprotein Metabolism, Atherosclerosis and Cardiomyopathy.- Heart Sphingolipids in Health and Disease.- Blood Sphingolipids in Homeostasis and Pathobiology.- Adipose Tissue and Ceramide Biosynthesis in the Pathogenesis of Obesity.- Sphingolipids and ...
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Sphingolipid metabolism, transport, and functions in plants: Recent progress and future perspectives
Plant Communications, 2021Chen Xiao-Ya +2 more
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Metabolic disorders of sphingolipid metabolism in man
Chemistry and Physics of Lipids, 1970openaire +2 more sources
Sphingolipid metabolism and complement signaling in cancer progression
Trends in Cancer, 2023Alhaji H. Janneh +2 more
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