Results 121 to 130 of about 45,038 (292)

List of sphingolipids significantly associated with DailySteps.

, 2018
List of sphingolipids significantly associated with DailySteps.
Sonia Davila (268093), Jonathan Jiunn Liang Yap (4891942), Steven G. Rozen (4891936), Jing Xian Teo (4891957), Swee Yaw Tan (3170187), Christopher Blöcker (4891948), Jing Quan Lim (4891933), Bin Tean Teh (227229), Chengxi Yang (4891939), Weng Khong Lim (4891945), Stuart Alexander Cook (3527294), Calvin Woon-Loong Chin (4891954), Jianhong Ching (2195713), Patrick Tan (18147), Chee Jian Pua (4891951), Anders Sahlén (4891960), Khung Keong Yeo (3170208)   +16 more
core   +1 more source

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

Med Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu, Weiquan Liao, Ziqi Lian, Mengdan Zhang, Chenxing Wang, Xingjia Zhu, Lin Zhang, Jian Chen, Zhichao Lu, Peipei Gong   +9 more
wiley   +1 more source

Sphingolipids

Sphingolipids are specialized lipids which function in lipid rafts located in the cell membrane. Their distribution is highly tissue specific. Genetic defects of lysosomal hydrolases and associated activator proteins required for sphingolipid degradation cause a specific group of lysosomal disorders referred to as sphingolipidoses.
van Kuilenburg, André B. P., Pop, Ana, Poorthuis, Ben J. H. M., Goorden, Susanna M. I.   +3 more
openaire   +3 more sources

Multitarget Regulatory Mechanisms and Research Advances of Plant‐Derived Bioactive Ingredients in Hypertension Prevention and Management

Phytotherapy Research, EarlyView.
Schematic overview of the multi‐target and multi‐pathway mechanisms of PDBI in the prevention and management of hypertension. ABSTRACT Hypertension remains a major global risk factor for cardiovascular diseases, yet current treatments face challenges such as suboptimal blood pressure control and inadequate organ protection.
Qiqi Deng, Yonglin Zhang, Jing Pan, Jing Luo, Hualin Sun, Chaonian Li, Li Li   +6 more
wiley   +1 more source

The bioactive sphingolipid playbook. A primer for the uninitiated as well as sphingolipidologists

Journal of Lipid Research
Sphingolipids and glycosphingolipids are among the most structurally diverse and complex compounds in the mammalian metabolome. They are well known to play important roles in biological architecture, cell-cell communication, and cellular regulation, and ...
Yusuf A. Hannun, Alfred H. Merrill, Jr., Chiara Luberto   +2 more
doaj   +1 more source

Protective Potentials of Natural Products Against Vascular Dementia: A Comprehensive Review of Experimental Studies

Phytotherapy Research, EarlyView.
ABSTRACT Vascular dementia (VaD), accounting for up to 20% of dementia cases globally, is primarily driven by chronic cerebral hypoperfusion (CCH), which leads to progressive cognitive impairment. Despite the increasing prevalence of VaD, effective treatments remain limited.
Jung‐Hoon Kim, Yongtaek Oh, Suin Cho
wiley   +1 more source

Diagnostic values of sphingolipids in plasma.

, 2015
Diagnostic values of sphingolipids in plasma.
Piotr Laudanski (74241), Karol Charkiewicz (743571), Slawomir Wolczynski (274548), Agnieszka Blachnio-Zabielska (603608), Monika Zbucka-Kretowska (743572)   +4 more
core   +1 more source

Reverse‐Engineered Lipid Nanoparticles Harness Protein Corona Formation for Cytokine Sequestration and Combination Immunomodulatory Therapy

Small, EarlyView.
Bioinspired triglyceride‐ceramide lipid nanoparticles were reverse‐engineered from cytokine‐sequestering plant‐derived nanoparticles to capture pathological inflammatory mediators through protein corona formation. Dexamethasone‐loaded TCNPs combine extracellular cytokine sequestration with intracellular immunomodulation, reducing IL‐6, TNF‐α, and NF‐κΒ
Junsik J. Sung, Gargi Yogesh Digholkar, Ryan M. Pearson   +2 more
wiley   +1 more source

Milk sphingolipids as functional components

Milk sphingomyelin (SM) and gangliosides represent key bioactive sphingolipids in dairy products increasingly recognized for their multifaceted health benefits.
Bhavbhuti M. Mehta, Shankar N. Mutkule, Essam Hebishy, Nivedita Datta   +3 more
core   +1 more source

Environmental Mycotoxins and Brain Health: Protective Role of Bromelain Against Fumonisin B1 in SH‐SY5Y Cells

Environmental Toxicology, EarlyView.
ABSTRACT Fumonisin B1 (FB1), a mycotoxin commonly found in contaminated food and feed, has been increasingly implicated in neurotoxicity, although its mechanisms remain poorly understood. This study investigates the neurotoxic potential of FB1 in human SH‐SY5Y neuroblastoma cells, both undifferentiated and RA‐differentiated, and evaluates the ...
Gianluca Antonio Franco, Francesca Inferrera, Nicla Tranchida, Davide Di Paola, Roberta Fusco, Salvatore Cuzzocrea, Enrico Gugliandolo   +6 more
wiley   +1 more source