Results 131 to 140 of about 52,176 (275)
Resynthesis of sphingomyelin from plasma-membrane phosphatidylcholine in BHK cells treated with Staphylococcus aureus sphingomyelinase [PDF]
, 1988 David Allan, Paul Quinn
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Expanding our understanding of synucleinopathies: proteinopathy, proteinopenia, and lipidopathy
The FEBS Journal, EarlyView.Neurodegeneration is thought to arise due to the disruption of the protein homeostasis. In synucleinopathies, alterations in the levels of functional and aggregated aSyn lead to proteinopenia and proteinopathy, respectively. aSyn and β‐glucocerebrosidase are closely linked to lipid metabolism, impacting organelle function and lipidostasis.
Manuel Flores‐León, Tiago F. Outeiro
wiley +1 more source
Lipid abnormalities in foam cell reticulosis of mice, an analogue of human sphingomyelin lipidosis
, 1969 Donald P. Fredrickson +2 more
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Extracellular vesicles in multiple myeloma: pathogenesis and therapeutic application
The FEBS Journal, EarlyView.Multiple myeloma is characterised by the clonal proliferation of plasma cells in the bone marrow. Extracellular vesicles (EVs) are a key component of cell‐to‐cell communication within the bone marrow microenvironment, promoting tumour growth, bone remodelling, immune modulation, angiogenesis and therapeutic resistance.
Chloe Wylie +3 more
wiley +1 more source
Lecithin/Sphingomyelin Ratios in Tracheal Aspirates from Newborn Infants [PDF]
, 1987 Mario D’Costa +2 more
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Gasdermins: multifunctional effectors of membrane permeabilization across cellular compartments
The FEBS Journal, EarlyView.Gasdermins (GSDMs) are pore‐forming proteins best known for driving pyroptosis through plasma membrane (PM) permeabilization. Beyond triggering inflammatory cell death, GSDMs can also associate with organelle membranes, including mitochondria, lysosomes, ER, and nucleus, where they modulate membrane integrity and cellular signaling.
Eleonora Margheritis +2 more
wiley +1 more source
International Journal of Cosmetic Science, EarlyView.The facial SC lipid profiles of young Chinese women in the early aging stage exhibited significant changes with age. The average chain length of diacylglycerol, triacylglycerol and short‐chain ceramides decreases with age, while the cholesteryl ester and ceramide EO subclasses increase. Some ceramides correlate positively with TEWL, skin elasticity and
Yumei Fan +6 more
wiley +1 more source
Journal of Microscopy, EarlyView.Abstract Malaria is one of the deadliest infectious diseases in the world, annually responsible for over 400,000 deaths. It is caused by parasites of the genus Plasmodium, which undergo remarkable structural changes during their development within different cells across various hosts.
Rachel Rachid +3 more
wiley +1 more source
Spatial metabolic and phenotypic characterization of the germ‐free mouse model
Annals of the New York Academy of Sciences, EarlyView.The germ‐free mouse model is a useful tool to understand the influence of the gut microbiota on host physiology. Using spatial metabolomics approaches we mapped the systemic location of small molecules in germ free and colonized mice, focusing on the intestine, spleen, lung, liver, and kidney.
Lauren Adams +8 more
wiley +1 more source