Results 131 to 140 of about 50,283 (222)

Lipid balance and chemoresistance in cancer cells. [PDF]

Elife
Kanemaru K, Nakamura Y.
europepmc   +1 more source

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang, Xue Sun, Xinhao Han, Xingda Zhang, Wenzheng Wang, Hongbin Wang, He Ren, Lina Gu   +7 more
wiley   +1 more source

Membrane composition-dependent patterning of Rho and F-actin in an artificial cell cortex. [PDF]

Mol Biol Cell
Schwarz GJ, Suber JR, Andhare D, Ragusa MJ, Landino J.   +4 more
europepmc   +1 more source

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Small, Volume 22, Issue 16, 17 March 2026.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti, Marius F.W. Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer A. Böckmann   +5 more
wiley   +1 more source

Synthetic Cells on Demand: From Molecular Stimuli to Cellular Functions

ChemSystemsChem, Volume 8, Issue 2, March 2026.
ABSTRACT Synthetic cells constructed via bottom‐up approaches using lipid or polymer vesicles have become essential tools for mimicking cellular functions and studying synthetic biological systems. These vesicles can undergo morphological changes and trigger internal reactions in response to external stimuli, such as osmotic pressure, temperature, pH ...
Masato Suzuki, Koki Kamiya
wiley   +1 more source

Ceramide metabolism in oxidative and glycolytic muscle: Significance for lipid-induced insulin resistance. [PDF]

Mol Metab
Eurén T, Flockhart M, Strmeň T, Zhou X, Horwath O, Apró W, Blackwood SJ, Tischer D, Moberg M, Steneberg P, Edlund H, Katz A, Chorell E.   +12 more
europepmc   +1 more source

SPHINGOMYELIN

Journal of Biological Chemistry, 1913
openaire   +1 more source

Stratum Corneum Ceramide Abnormalities in Atopic Dermatitis: Pathophysiology and Implications for Disease Management

The Journal of Dermatology, Volume 53, Issue 3, Page 380-387, March 2026.
ABSTRACT The stratum corneum, as the outermost layer of the skin, functions as a critical barrier that maintains cutaneous hydration and systemic homeostasis. Among its structural lipids, ceramides constitute the most abundant and diverse component. These molecules are essential for the formation of lamellar structures that secure barrier integrity ...
Takashi Sakai
wiley   +1 more source

Chemotherapy resistance due to epithelial-to-mesenchymal transition is caused by abnormal lipid metabolic balance. [PDF]

Elife
Matsumoto A, Inoko A, Tanaka T, Konishi GI, Hosoda W, Kojima T, Ohnishi K, Ikenouchi J.   +7 more
europepmc   +1 more source

Intergenerational Transmission of Metabolic Changes in Oocytes From Aged Mice

Aging Cell, Volume 25, Issue 3, March 2026.
This study shows that oxidative changes in oocytes from aged female mice lead to lipid droplet accumulation and altered energy and retinoid metabolism. These changes persist in embryonic organs, triggering antioxidant responses in lipid‐rich tissues. Remarkably, altered profiles are transmitted across generations, reaching third generation, suggesting ...
Hafsa Gulzar, Richard Musson, Simona Bisogno, Lulu Alluhaibi, Alexey Maximenko, Ewelina Bik, Małgorzata Barańska, Joanna Depciuch, Grażyna E. Ptak   +8 more
wiley   +1 more source