Results 151 to 160 of about 50,283 (222)

Liver Metabolomic Profiling Reveals Distinct Signatures Between Steatosis and Metabolic Dysfunction‐Associated Steatohepatitis

Liver International, Volume 46, Issue 3, March 2026.
ABSTRACT Background and Aims Metabolic dysfunction‐associated steatotic liver disease (MASLD), the most common chronic liver disease worldwide, is closely linked to obesity and metabolic syndrome. The reason some patients with MASLD develop metabolic dysfunction‐associated steatohepatitis (MASH) and which metabolic changes in the liver are linked to ...
Saana Palomurto, Emily Flam, Dorota Kaminska, Kirsi A. Virtanen, Vesa Kärjä, Pirjo Käkelä, Päivi Pajukanta, Delphine Eberlé, Joel T. Haas, Violeta Raverdy, Robert Caiazzo, François Pattou, Bart Staels, Jussi Pihlajamäki, Ville Männistö   +14 more
wiley   +1 more source

Pathogenic Variants and Olipudase Alfa Treatment of Patients With Acid Sphingomyelinase Deficiency in Taiwan. [PDF]

Mol Genet Genomic Med
Lin HH, Chen HA, Lin SJ, Hsu RH, Lee NC, Hwu WL, Ni YH, Chou YY, Chiu PC, Peng SS, Chien YH.   +10 more
europepmc   +1 more source

Eggs and Associated Nutrients: Implications for Brain Development and Function From Conception to Early Adulthood: A Narrative Review

Nutrition Bulletin, Volume 51, Issue 1, Page 46-66, March 2026.
ABSTRACT Brain development is an ongoing process that occurs throughout the first 1000 days of life (conception until 2 years) and proceeds throughout childhood, adolescence and up until early adulthood. Adequate nutrient intakes are crucial for both neurodevelopment inside the womb and critical life‐stages thereafter when the brain continues to grow ...
Emma J. Derbyshire
wiley   +1 more source

Autosomal recessive <i>ELOVL1</i>-related disorder presenting with severe neonatal cholestasis: A novel clinical feature? [PDF]

Mol Genet Metab Rep
Tsai AC, Lee HT, Sanchez B, Huang YR, Krysinski S, Zalan A, Falsey E.   +6 more
europepmc   +1 more source

Plant Lipid Droplets and Derived Lipidic Nano‐Assemblies: Structure, Biogenesis and Pharmaceutical Applications

Plant Biotechnology Journal, Volume 24, Issue 3, Page 1322-1343, March 2026.
ABSTRACT Lipid droplets (LDs) serve as the primary storage site for neutral lipids in plant cells, with growing evidence supporting many additional biological roles, such as in lipid homeostasis, signalling, trafficking, inflammatory responses and inter‐organelle communication.
Abdulsamie Hanano, Amal Yousfan, Denis J. Murphy   +2 more
wiley   +1 more source

Sphingomyelin synthase inhibitors from edible mushrooms prevent overweight and improve vitamin D homeostasis in a mouse model of diet-induced obesity. [PDF]

Front Nutr
Enkhbat E, Murai Y, Yuyama K, Sun H, Swamy MMM, Suga Y, Anetai M, Monde K.   +7 more
europepmc   +1 more source

Developing giant plasma membrane vesicles from Leishmania cells to investigate the role of membrane proteins in photodynamic inactivation

Photochemistry and Photobiology, Volume 102, Issue 2, Page 480-488, March/April 2026.
In this study, we developed giant plasma membrane vesicles (GPMVs) from Leishmania amazonensis promastigote membranes to investigate the role of protein‐embedded membranes in methylene blue (MB) photooxidation. Upon MB photoactivation in model lipid membranes (giant unilamellar vesicles, GUVs), a distinct photooxidation effect was observed, marked by ...
Maressa D. F. de Souza, Pietro Ciancaglini, Rosangela Itri, Martha S. Ribeiro   +3 more
wiley   +1 more source

Microbiota-sphingolipid pathway in generalized epilepsy: evidence from Mendelian randomization and clinical metabolomics. [PDF]

Front Microbiol
Gong J, Lin M, Chen L, Xiong W, Zhang Y, Liu C, Chen S, Lin W, Zhu C, Huang H.   +9 more
europepmc   +1 more source

Characterization of Phytoene Desaturase Knockout Carotenoid‐Deficient Microalgal Mutants Generated by Cas9‐Ribonucleoprotein Complexes

Physiologia Plantarum, Volume 178, Issue 2, March/April 2026.
ABSTRACT Phytoene desaturase (PDS; EC 1.3.5.5) is a key enzyme of the carotenoid biosynthetic pathway, catalyzing the desaturation of phytoene, precursor of all carotenoids. In this study, several PDS‐knockout (PDS‐KO) transformants of the chlorophyte microalga Chlamydomonas reinhardtii were generated using a reverse genetics strategy. Two single guide
Ana Molina‐Márquez, Simon Kelterborn, Peter Hegemann, Miguel Pérez‐Rodríguez, Javier Vigara, Rosa León   +5 more
wiley   +1 more source

Proteomic Profiling of an Exosome-Enriched Extracellular Vesicle Fraction and Structural Characterization of SMPDL3A in the Carcinogenic Liver Fluke Clonorchis sinensis. [PDF]

Int J Mol Sci
Kim SH, Yang D, Bae YA.
europepmc   +1 more source