Results 161 to 170 of about 52,176 (275)

Myelin Lipid Composition in the Central Nervous System Is Regionally Distinct and Requires Mechanistic Target of Rapamycin Signaling

open access: yesGlia, Volume 73, Issue 9, Page 1841-1859, September 2025.
Main Points Brain oligodendrocytes have lower rates of cholesterol synthesis and higher rates of lipoprotein uptake than spinal cord oligodendrocytes. Myelin lipid content is higher in CNS regions with larger average axon diameter. Brain and spinal cord myelin cholesterol content is innately different, while myelin fatty acid content can be modulated ...
Marie L. Mather   +4 more
wiley   +1 more source

Molecular Maestro in the Lung: The Sphingolipid Rheostat. [PDF]

open access: yesAm J Respir Cell Mol Biol
Rojas-Quintero J, Polverino F.
europepmc   +1 more source

Heavy Metals Toxicity: Mechanism, Health Effects, and Therapeutic Interventions

open access: yesMedComm, Volume 6, Issue 9, September 2025.
Heavy metals exert a wide range of effects at the cellular, molecular, and genetic levels, leading to neurological damage, renal dysfunction, cardiovascular disease, reproductive developmental abnormality, immune system abnormality, and increased risk of cancer by interfering with biomolecule function, signaling pathways, inducing oxidative stress, and
Yu‐feng Cheng   +3 more
wiley   +1 more source

Plasma Sphingomyelin Level as a Risk Factor for Coronary Artery Disease [PDF]

open access: green, 2000
Xian-Cheng Jiang   +7 more
openalex   +1 more source

Exosomes in Metabolic Diseases: From Molecular Mechanisms to Clinical Applications

open access: yesMedComm – Future Medicine, Volume 4, Issue 3, September 2025.
We summarize recent progress in exosome biology and elucidate their roles in interorgan communication networks underlying metabolic pathogenesis. We also comprehensively examine the evolving application of exosomes in metabolic disease management, with a focus on critically evaluating preclinical and clinical advances in exosome‐mediated therapeutic ...
Yanting Wu   +3 more
wiley   +1 more source

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