Results 201 to 210 of about 50,283 (222)
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Biological functions of sphingomyelins
Progress in Lipid Research, 2013Sphingomyelin (SM) is a dominant sphingolipid in membranes of mammalian cells and this lipid class is specifically enriched in the plasma membrane, the endocytic recycling compartment, and the trans Golgi network. The distribution of SM and cholesterol among cellular compartments correlate.
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Lateral diffusion in sphingomyelin bilayers
Magnetic Resonance in Chemistry, 2010AbstractSphingomyelin (SM) is an important lipid of eukaryotic cellular membranes and neuronal tissues. We studied lateral diffusion in macroscopically oriented bilayers of synthetic palmitoylsphingomyelin (PSM) and natural sphingomyelins of egg yolk (eSM), bovine brain (bSM) and bovine milk (mSM) by pulsed field gradient NMR (PFG NMR) in the ...
Filippov A., Rudakova M., Munavirov B.
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Structural diversity of sphingomyelin microdomains
Ultramicroscopy, 2004In cells plasma membrane, sphingomyelin (SM) plays a key role in the formation of a category of lipid microdomains enriched in cholesterol (Chl) often referred to as rafts. Atomic force microscopy (AFM) was used to analyze the mesoscopic topography of enriched SM microdomains in supported bilayers made of SM/dioleoylphosphatidylcholine (SM/DOPC) and SM/
Marie-Cécile, Giocondi +3 more
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2020
Sphingolipids play important roles in apoptosis, differentiation, senescence, proliferation, and inflammation. The sphingomyelin (SM) cycle, with the key components of SM, sphingomyelinase (SMase) and ceramide, has received substantial attention to date because of its role in cell signaling.
Heather Hayter, Yusuf A. Hannun
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Sphingolipids play important roles in apoptosis, differentiation, senescence, proliferation, and inflammation. The sphingomyelin (SM) cycle, with the key components of SM, sphingomyelinase (SMase) and ceramide, has received substantial attention to date because of its role in cell signaling.
Heather Hayter, Yusuf A. Hannun
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Sphingomyelin breakdown and cell fate
Trends in Biochemical Sciences, 1996A growing number of cell-surface receptors are now being shown to generate signals that trigger the hydrolysis of sphingomyelin to release diffusible ceramides. Ceramides have been implicated as key mediators in signaling pathways, with outcomes as diverse as cell proliferation, differentiation, growth arrest and apoptosis. The response depends on cell
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Sphingomyelin: biophysical aspects
Chemistry and Physics of Lipids, 1999Y, Barenholz, T E, Thompson
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Sphingomyelin: Enzymatic Reactions
1970Total synthesis and total degradation of sphingomyelin can now be accomplished with isolable enzymes. Some of these have been purified and partially characterized. Most preparations are overwhelmingly crude. Nevertheless, substantial progress has been made toward understanding the enzymatic reactions of sphingomyelin.
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