Results 51 to 60 of about 50,209 (150)

Mechanisms involved in cellular ceramide homeostasis

Nutrition & Metabolism, 2012
Sphingolipids are ubiquitous and critical components of biological membranes. Their biosynthesis starts with soluble precursors in the endoplasmic reticulum and culminates in the Golgi complex and plasma membrane. Ceramides are important intermediates in
Hussain M, Jin Weijun, Jiang Xian-Cheng
doaj   +1 more source

Separation of molecular species of sphingomyelin by reversed-phase high-performance liquid chromatography.

Journal of Lipid Research, 1979
A convenient method for the separation of molecular species of sphingomyelin by reversed-phase high-performance liquid chromatography (HPLC) is described.
F B Jungalwala, V Hayssen, J M Pasquini, R H McCluer   +3 more
doaj   +1 more source

Sphingomyelin and ceramide-phosphoethanolamine synthesis by microsomes and plasma membranes from rat liver and brain.

Journal of Lipid Research, 1987
Pulse-chase experiments showed that phosphatidylethanolamine (PE) was the direct precursor for ceramide-phosphoethanolamine, a sphingomyelin analogue, in the same way as phosphatidylcholine was for sphingomyelin.
M Malgat, A Maurice, J Baraud
doaj   +1 more source

Circulating Lipoprotein Sphingolipids in Chronic Kidney Disease with and without Diabetes

Biomedicines
Abnormalities of sphingolipid metabolism play an important role in diabetes. We compared sphingolipid levels in plasma and in isolated lipoproteins between healthy control subjects and two groups of patients, one with chronic kidney disease without ...
Maria F. Lopes-Virella, Samar M. Hammad, Nathaniel L. Baker, Richard L. Klein, Kelly J. Hunt   +4 more
doaj   +1 more source

Review and targeted lipidomic biomarkers in atherosclerosis

Российский кардиологический журнал
Ischemic cardiovascular events (ischemic stroke, myocardial infarction) are the most common complications of cardiovascular diseases. One of the leading mechanisms of these complications is atherosclerosis.
A. A. Lomonosova, D. G. Gognieva, M. G. Abdullaev, A. S. Kostikova, N. N. Eroshchenko, A. A. Nartova, A. S. Silantyev, A. Yu. Suvorov, R. N. Komarov, A. N. Dzyundzya, D. Yu. Shchekochikhin, E. A. Syrkina, F. Yu. Kopylov   +12 more
doaj   +1 more source

Sphingomyelin [PDF]

, 2018
K. J. Lackner, D. Peetz
openaire   +2 more sources

Urinary lipid metabolites and progression of kidney disease in individuals with type 2 diabetes

Frontiers in Endocrinology
ObjectiveA substantial proportion of individuals with type 2 diabetes (T2D) experience a fast decline (FD) in kidney function, a high-risk phenotype not reliably identified by current clinical markers.
Yu Xiao, Caifeng Shi, Songyan Qin, Aiqin He, Xiaomei Wu, Chunsun Dai, Yang Zhou   +6 more
doaj   +1 more source

Sphingomyelin regulates astrocyte activity by regulating NF-κB signaling via HDAC1/3 expression

Journal of Lipid Research
Astrocytes comprise approximately 40% of CNS cells and have pivotal roles in brain functions. Under steady-state conditions, astrocytes maintain homeostasis in the CNS through the uptake or release of neurotransmitters.
Ryo Kadowaki, Hana Hirose, Gai Takimoto, Takafumi Kohama, Hiroyuki Nakamura   +4 more
doaj   +1 more source

Trifunctional sphingomyelin derivatives enable nanoscale resolution of sphingomyelin turnover in physiological and infection processes via expansion microscopy

Nature Communications
Sphingomyelin is a key molecule of sphingolipid metabolism, and its enzymatic breakdown is associated with various infectious diseases. Here, we introduce trifunctional sphingomyelin derivatives that enable the visualization of sphingomyelin distribution
Marcel Rühling, Louise Kersting, Fabienne Wagner, Fabian Schumacher, Dominik Wigger, Dominic A. Helmerich, Tom Pfeuffer, Robin Elflein, Christian Kappe, Markus Sauer, Christoph Arenz, Burkhard Kleuser, Thomas Rudel, Martin Fraunholz, Jürgen Seibel   +14 more
doaj   +1 more source

Studies on cerebral sphingomyelin [PDF]

Biochemical Journal, 1961
G B, ANSELL, S, SPANNER
openaire   +2 more sources