Results 151 to 160 of about 13,482,017 (199)

A Contemporary Pathomechanistic Nosology of Inherited Lysosomal Disorders. [PDF]

J Inherit Metab Dis
McCarron EP, Blau N, Eden ER, Platt FM, Aerts JM, Jones SA, Ferreira CR, Stepien KM.   +7 more
europepmc   +1 more source

Measles virus reprograms CD4⁺ T-cell sphingolipid and fatty acid metabolism to facilitate infection. [PDF]

Front Cell Dev Biol
Grijalva Yépez MF, Cordes YL, Fekete A, Schumacher F, Kleuser B, Avota E.   +5 more
europepmc   +1 more source

A genome-wide screen in <i>Pseudomonas aeruginosa</i> identifies genes impacting production of the hemolytic phospholipase C/sphingomyelinase, PlcH. [PDF]

J Bacteriol
Schutz K, Evans OF, Mackinder JR, DiGianivittorio P, Patwardhan A, Wargo MJ.   +5 more
europepmc   +1 more source

Reduction of sphingomyelinase activity associated with progranulin deficiency and frontotemporal dementia. [PDF]

Neurobiol Dis
Boyle NR, Fox SN, Tadepalli AS, Seyfried NT, Kukar T, Ramos EM, Nana AL, Spina S, Grinberg LT, Miller BL, Seeley WW, Arrant AE, Roberson ED.   +12 more
europepmc   +1 more source

A kidney-protective mechanism via cellular oxidative stress reduction induced by CD5L protein. [PDF]

Cell Death Discov
Kudo K, Ikeda T, Ikeda K, Maehara N, Hirota A, Yoshikawa Y, Mori H, Takayama M, Yasuda K, Tezuka T, Takagi T, Arai S, Miyazaki T.   +12 more
europepmc   +1 more source

Development of a FRET-Based Assay for Human Neutral Sphingomyelinase 2. [PDF]

Biochemistry
Aywa KM, Kappe C, Ghandour B, Gao S, Arenz C, Hannun YA, Airola MV.   +6 more
europepmc   +1 more source

A Retrospective Chart Review Study on the Burden of Illness of Acid Sphingomyelinase Deficiency in Brazil. [PDF]

J Clin Med
Giugliani R, Siqueira ACM, Martins AM, Marcondes BF, Souza CFM, Dain Gandelman Horovitz D, Leão EKE, Gusto G, Carvalho GDS, Artigalás O, Boy R, Stefani RR, Rawat NS, Konidaris G.   +13 more
europepmc   +1 more source

Acid Sphingomyelinase Deficiency: A Clinical and Immunological Perspective [PDF]

International Journal of Molecular Sciences, 2021
Acid sphingomyelinase deficiency (ASMD) is a lysosomal storage disease caused by deficient activity of acid sphingomyelinase (ASM) enzyme, leading to the accumulation of varying degrees of sphingomyelin.
Andrea Elena Dardis, Macedo Mf, Diana Sousa   +2 more
exaly   +2 more sources

Sphingomyelinase Disables Inactivation in Endogenous PIEZO1 Channels [PDF]

Cell Reports, 2020
Endogenous PIEZO1 channels of native endothelium lack the hallmark inactivation often seen when these channels are overexpressed in cell lines. Because prior work showed that the force of shear stress activates sphingomyelinase in endothelium, we ...
Antreas Kalli, David Beech, Dario de Vecchis   +2 more
exaly   +2 more sources

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The phylogenetic distribution of sphingomyelinase D activity in venoms of Haplogyne spiders

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2003
The venoms of Loxosceles spiders cause severe dermonecrotic lesions in human tissues. The venom component sphingomyelinase D (SMD) is a contributor to lesion formation and is unknown elsewhere in the animal kingdom. This study reports comparative analyses of SMD activity and venom composition of select Loxosceles species and representatives of closely ...
Greta J, Binford, Michael A, Wells
openaire   +2 more sources