Results 11 to 20 of about 8,712 (201)
Hepatology, EarlyView., 2022 Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario +12 more
wiley +1 more source
Correlation between metabolomic profile constituents and feline pancreatic lipase immunoreactivity
Journal of Veterinary Internal Medicine, 2022 Background Feline pancreatic lipase immunoreactivity (fPLI) is commonly used to diagnose pancreatitis in cats (FP). Untargeted metabolomics has been extensively applied in human and veterinary medicine, but no metabolomic studies regarding FP have been ...
Magdalena Maria Krasztel +5 more
doaj +1 more source
Journal of Lipid Research, 2014 Gangliosides and sulfatides (STs) are acidic glycosphingolipids (GSLs) that have one or more sialic acids or sulfate substituents, in addition to neutral sugars, attached to the C-1 hydroxyl group of the ceramide long chain base. TLC is a widely employed
Hyejung Park +2 more
doaj +1 more source
Imaging Mass Spectrometry Reveals Acyl-Chain- and Region-Specific Sphingolipid Metabolism in the Kidneys of Sphingomyelin Synthase 2-Deficient Mice. [PDF]
PLoS ONE, 2016 Obesity was reported to cause kidney injury by excessive accumulation of sphingolipids such as sphingomyelin and ceramide. Sphingomyelin synthase 2 (SMS2) is an important enzyme for hepatic sphingolipid homeostasis and its dysfunction is considered to ...
Masayuki Sugimoto +10 more
doaj +1 more source
Tear Film Amphiphilic and Anti-Inflammatory Lipids in Bovine Pink Eye
Metabolites, 2018 Background: Tear film fluid serves as a dynamic barrier that both lubricates the eye and protects against allergens and infectious agents. However, a detailed analysis of a bacteria-induced immune response on the tear film lipidome has not been ...
Paul L. Wood +6 more
doaj +1 more source
Journal of Lipid Research, 2019 Quantitatively and rapidly analyzing lipids is necessary to elucidate their biological functions. Herein, we developed a quantitative method for various lipid classes using supercritical fluid chromatography (SFC) coupled with a charged aerosol detector (
Hiroaki Takeda +4 more
doaj +1 more source
Membrane properties of sphingomyelins [PDF]
FEBS Letters, 2002 Sphingomyelin and phosphatidylcholine are important components in the external leaflet of cellular plasma membranes. In this review we compare the structure of these lipid molecules, with emphasis on the differences in hydrogen bonding capacity and membrane properties that arise from the small but significant differences in molecular structure.
Ramstedt, Bodil, Slotte, J.Peter
openaire +2 more sources
Experimental Biology and Medicine, 1964 SummaryThe sphingomyelin region of human plasma lipids, entirely free from lecithin, has been fractionated into two components by thin-layer chromatography. Both components had properties characteristic of sphingomyelins, but markedly different fatty acid patterns, acids above C20 being concentrated in the less-polar material.
P D, WOOD, S, HOLTON
openaire +2 more sources
Diagnostics, 2021 Systemic sclerosis (SSc) is an autoimmune disease with fibrosis of the skin and/or internal organs, causing a decrease in quality of life and survival. There is no causative therapy, and the pathophysiology of the SSc remains unclear. Studies showed that
Marija Geroldinger-Simić +4 more
doaj +1 more source
Improved quantitation of plasma lipids by direct gas-liquid chromatography
Journal of Lipid Research, 1969 A preliminary digestion of total plasma lipid extracts with phospholipase C, which converts the lysolecithins, lecithins, and sphingomyelins into monoglycerides, diglycerides, and ceramides, respectively, has been shown to facilitate subsequent ...
A. Kuksis, O. Stachnyk, B.J. Holub
doaj +1 more source