Results 211 to 220 of about 84,454 (251)

Sphingosine 1-phosphate receptors

Prostaglandins & Other Lipid Mediators, 2001
Sphingosine-1-phosphate (SPP) is a bioactive lipid produced from the metabolism of sphingomyelin. It is an important constituent of serum and regulates cell growth, survival, migration, differentiation and gene expression. Its mode of action has been enigmatic; however, recent findings have shown that a family of G-protein-coupled receptors (GPCR) of ...
openaire   +2 more sources

Sphingosine-1-Phosphate Phosphatases

Prostaglandins & Other Lipid Mediators, 2001
Sphingosine-1-phosphate is a potent proliferative, survival, and morphogenetic factor, acting as an extracellular ligand for the EDG family of G-protein-coupled receptors and possibly intracellularly through as yet, unidentified targets. It is produced within most, if not all cells by phosphorylation of sphingosine, and is an abundant serum lipid that ...
openaire   +2 more sources

Sphingosine in apoptosis signaling

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2002
The sphingolipid metabolites ceramide, sphingosine, and sphingosine 1-phosphate contribute to controlling cell proliferation and apoptosis. Ceramide and its catabolite sphingosine act as negative regulators of cell proliferation and promote apoptosis. Conversely, sphingosine 1-phosphate, formed by phosphorylation of sphingosine by a sphingosine kinase,
openaire   +2 more sources

Sphingosine 1-phosphate receptor modulators in multiple sclerosis and other conditions

Lancet, The, 2021
Jeffrey A Cohen
exaly  

Glycosphingolipids (Sugar-Sphingosine Conjugates)

1969
Publisher Summary Glycosphingolipids are a group of sphingolipids containing mono or oligosaccharide residues. The sugar residues are in direct or indirect glycosidic conjugation with the primary hydroxyl group of the N -acylated sphingosine or dihydrosphingosine molecule.
openaire   +2 more sources

Sphingosine

2007
S.J. Enna, David B. Bylund
openaire   +1 more source

Sphingosine and Sphingosine 1 Phosphate in the Brain

2011
Sphingosine is an 18-carbon amino alcohol with an unsaturated hydrocarbon chain. It is found in sphingolipids (cerbroside, sulfatide, and ganglioside) as well as phospholipid (sphingomyelin) (Fig. 9.1). Sphingomyelin (SM) is the major membrane sphingolipid and is the precursor for ceramide and sphingosine.
openaire   +1 more source

Sphingosine

2008
openaire   +2 more sources

Very-long-chain fatty acids induce glial-derived sphingosine-1-phosphate synthesis, secretion, and neuroinflammation

Cell Metabolism, 2023
Hyunglok Chung, Ye-Jin Park, Zhongyuan Zuo   +2 more
exaly  

Über Sphingosin

Hoppe-Seyler´s Zeitschrift für physiologische Chemie, 1955
E. Klenk, H. Faillard
openaire   +1 more source