Results 111 to 120 of about 27,038 (199)

Targeting sphingosine kinase 1 in p53KO thymic lymphoma. [PDF]

FASEB J, 2023
Velazquez FN, Stith JL, Zhang L, Allam AM, Haley J, Obeid LM, Snider AJ, Hannun YA.   +7 more
europepmc   +1 more source

S1pping fire: Sphingosine-1-phosphate signaling as an emerging target in inflammatory bowel disease and colitis-associated cancer

Clinical and Experimental Gastroenterology, 2014
Emilie Degagné, Julie D Saba Children's Hospital Oakland Research Institute, Oakland, CA, USA Abstract: Inflammatory bowel disease (IBD) is a complex disease that involves unpredictable and destructive inflammation in the gastrointestinal ...
Degagné E, Saba JD
doaj  

Expression of a catalytically inactive sphingosine kinase mutant blocks agonist-induced sphingosine kinase activation. A dominant-negative sphingosine kinase.

The Journal of biological chemistry, 2000
Sphingosine kinase (SK) catalyzes the formation of sphingosine 1-phosphate (S1P), a lipid messenger that plays an important role in a variety of mammalian cell processes, including inhibition of apoptosis and stimulation of cell proliferation. Basal levels of S1P in cells are generally low but can increase rapidly when cells are exposed to various ...
S M, Pitson, P A, Moretti, J R, Zebol, P, Xia, J R, Gamble, M A, Vadas, R J, D'Andrea, B W, Wattenberg   +7 more
openaire   +1 more source

Integrative roles of sphingosine kinase in liver pathophysiology. [PDF]

Toxicol Res, 2023
Kim KM, Shin EJ, Yang JH, Ki SH.
europepmc   +1 more source

Therapeutic potential of the sphingosine kinase 2 inhibitor opaganib. [PDF]

Pharm Sci Adv
Huang F, Zhan P, Shi X, Sun Y, Song X, Sun P, Liu B.   +6 more
europepmc   +1 more source

Vascular Sphingosine Kinase 1 Regulates Angiotensin II-Induced Hypertension. [PDF]

Hypertension
Jozefczuk E, Szczepaniak P, Mikolajczyk TP, Nosalski R, Dziedzic M, Urbanski K, Wojciechowska E, Filip G, Stefanska M, Blyszczuk P, Guzik TJ, Siedlinski M.   +11 more
europepmc   +1 more source

UCHL1 Regulates Radiation Lung Injury via Sphingosine Kinase-1. [PDF]

Cells, 2023
Epshtein Y, Mathew B, Chen W, Jacobson JR.   +3 more
europepmc   +1 more source

Sphingolipid Expression During Corneal Wound Healing in a Sphingosine Kinase 1 Knockout Model. [PDF]

Cells
Basu SK, Mabry S, Nsiah P, Nicholas SE, Lenchik N, Altawil M, Chiu CY, Stephenson DJ, Chalfant CE, Karamichos D, Mandal N.   +10 more
europepmc   +1 more source

Sphingosine kinase 1 is dysregulated via hypoxia-inducible factor 1α in oral squamous cell carcinoma. [PDF]

Indian J Med Res
Pandey R, Vishwakarma S, Gupta V, Arya N, Das S, Chowdhary R, Kumar A.   +6 more
europepmc   +1 more source

Sphingosine kinase 1 is integral for elastin deficiency-induced arterial hypermuscularization. [PDF]

Nat Cardiovasc Res
Saito J, Dave JM, Gallardo-Vara E, Sadagopan N, Kabir I, Tellides G, Riemer RK, Urban Z, Spiegel S, Hla T, Greif DM.   +10 more
europepmc   +1 more source