Results 151 to 160 of about 26,969 (190)

Role of Sphingosine Kinase 1 in Glucolipotoxicity-Induced Early Activation of Autophagy in INS-1 Pancreatic β Cells. [PDF]

Cells
Coant N, Rendja K, Bellini L, Flamment M, Lherminier J, Portha B, Codogno P, Le Stunff H.   +7 more
europepmc   +1 more source

Retracted: The Expression and Clinical Significance of Sphingosine Kinase 1 and Vascular Endothelial Growth Factor in Endometrial Carcinoma. [PDF]

Emerg Med Int
International EM.
europepmc   +1 more source

Combating Acute Myeloid Leukemia via Sphingosine Kinase 1 Inhibitor-Nanomedicine Combination Therapy with Cytarabine or Venetoclax. [PDF]

Pharmaceutics
Nguyen TM, Joyce P, Ross DM, Bremmell K, Jambhrunkar M, Wong SS, Prestidge CA.   +6 more
europepmc   +1 more source

Inhibition of Sphingosine Kinase 1 Reduces Sphingosine-1-Phosphate and Exacerbates Amyloid-Beta-Induced Neuronal Cell Death in Mixed-Glial-Cell Culture. [PDF]

Neurol Int
Minamihata T, Takano-Kawabe K, Moriyama M.   +2 more
europepmc   +1 more source

Assessment of the Effects of Sphingosine Kinase 1/Sphingosine-1-Phosphate on Microangiogenesis at Rat Myofascial Trigger Points Using Contrast-Enhanced Ultrasonography. [PDF]

J Pain Res
Fang X, Yin Y, Lun H, Liu Y, Zhu S.
europepmc   +1 more source

[Sphingosine kinase-1 regulates migration and invasion of gastric cancer cells via targeting the nuclear factor-κB signaling pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Ling Q, Ji K, Chen J, Guan J, Wang R, Man W, Zhu B.   +6 more
europepmc   +1 more source

Expression of Concern: miRNA-103 promotes chondrocyte apoptosis by downregulation of Sphingosine kinase-1 and ameliorates PI3K/AKT pathway in osteoarthritis. [PDF]

Biosci Rep
europepmc   +1 more source

Sphingosine kinase 1-specific inhibitor PF543 reduces goblet cell metaplasia of bronchial epithelium in an acute asthma model.

Am J Physiol Lung Cell Mol Physiol
Sudhadevi T, Ackerman SJ, Jafri A, Basa P, Ha AW, Natarajan V, Harijith A.   +6 more
europepmc   +1 more source

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Discovery of novel sphingosine kinase 1 inhibitors

Bioorganic and Medicinal Chemistry Letters, 2009
Sphingosine kinase 1 (SK1) is an important enzyme that regulates the balance between ceramide and sphingosine-1-phosphate (S1P). Potent and novel SK1 inhibitors (6ag, 9ab and 12aa) have been discovered through a series of modifications of sphingosine (1), the substrate of this enzyme.
Yibin, Xiang, Gary, Asmussen, Michael, Booker, Bradford, Hirth, John L, Kane, Junkai, Liao, Kevin D, Noson, Christopher, Yee   +7 more
exaly   +3 more sources