Results 171 to 180 of about 371,184 (271)

Acid ceramidase-1 (ASAH1/aCDase) an important for anticancer drug discovery: a review

Future Journal of Pharmaceutical Sciences
Background Dysregulated sphingolipid metabolism has emerged as a major pathway in multiple human cancers. Sphingolipids are major structural components of cell membranes, playing key roles in maintaining structural integrity, fluidity, and barrier ...
Seemarani M. Pawar, Trupti Chitre, Prasad Dandawate   +2 more
doaj   +1 more source

Sphingosine kinase 1 contributes to the metastatic potential of epithelial ovarian cancer to the adipocyte-rich niche. [PDF]

Exp Hematol Oncol, 2022
Wang C, Ye T, Wang W, Song K, Zhu J, Dai L, Di W.   +6 more
europepmc   +1 more source

Sphingosine kinase 1 (SPHK1); sphingosine 1-phosphate receptor [PDF]

Science-Business eXchange, 2014
openaire   +1 more source

Evaluation of ellagic acid as an inhibitor of sphingosine kinase 1: A targeted approach towards anticancer therapy.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019
Preeti Gupta, Taj Mohammad, Parvez Khan, M. Alajmi, A. Hussain, M. Rehman, M. Hassan   +6 more
semanticscholar   +1 more source

Sphingosine kinase 1 promotes tumor immune evasion by regulating the MTA3-PD-L1 axis. [PDF]

Cell Mol Immunol, 2022
Lau P, Zhang G, Zhao S, Liang L, Zhang H, Zhou G, Hung MC, Chen X, Liu H.   +8 more
europepmc   +1 more source

Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia.

Blood, 2017
J. Powell, Alexander C Lewis, Wenying Zhu, John Toubia, M. Pitman, C. Wallington-Beddoe, P. Moretti, D. Iarossi, S. Samaraweera, N. Cummings, H. Ramshaw, Daniel Thomas, A. Wei, Angel F. Lopez, R. D’Andrea, I. Lewis, S. Pitson   +16 more
semanticscholar   +1 more source

Sphingosine kinase 1 (SPHK1) [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

Sphingosine Kinase-1 Is Overexpressed and Correlates with Hypoxia in Osteosarcoma: Relationship with Clinicopathological Parameters. [PDF]

Cancers (Basel), 2022
Gomez-Brouchet A, Illac C, Ledoux A, Fortin PY, de Barros S, Vabre C, Despas F, Peries S, Casaroli C, Bouvier C, Aubert S, de Pinieux G, Larousserie F, Galmiche L, Talmont F, Pitson S, Maddelein ML, Cuvillier O.   +17 more
europepmc   +1 more source

Role of Sphingosine Kinase 1 and Sphingosine-1-Phosphate Axis in Hepatocellular Carcinoma.

Handbook of Experimental Pharmacology, 2019
Michael Maceyka, Timothy D. Rohrbach, S. Milstien, S. Spiegel   +3 more
semanticscholar   +1 more source

The anti-osteosarcoma cell activity by the sphingosine kinase 1 inhibitor SKI-V. [PDF]

Cell Death Discov, 2022
Sun X, Shan HJ, Yin G, Zhang XY, Huang YM, Li HJ.   +5 more
europepmc   +1 more source