δ-Ctenitoxin-Pn1a, a Peptide from Phoneutria nigriventer Spider Venom, Shows Antinociceptive Effect Involving Opioid and Cannabinoid Systems, in Rats [PDF]
Toxins, 2016 PnTx4(6-1), henceforth renamed δ-Ctenitoxin-Pn1a (δ-CNTX-Pn1a), a peptide from Phoneutria nigriventer spider venom, initially described as an insect toxin, binds to site 3 of sodium channels in nerve cord synaptosomes and slows down sodium current ...
Bruna Luiza Emerich +7 more
openalex +2 more sources
Dissecting the contributions of membrane affinity and bivalency of the spider venom protein DkTx to its sustained mode of TRPV1 activation. [PDF]
J Biol Chem, 2023 Singh Y +8 more
europepmc +3 more sources
Comparative venomics suggests an evolutionary adaption of spider venom from predation to defense. [PDF]
Commun BiolLüddecke T +8 more
europepmc +3 more sources
Toxinology in the proteomics era: a review on arachnid venom proteomics [PDF]
Journal of Venomous Animals and Toxins including Tropical Diseases, 2022 The word venomics was coined to acknowledge the studies that use omics to investigate venom proteins and peptides. Venomics has evolved considerably over the last 20 years. The first works on scorpion or spider venomics were published in the early 2000’s.
Filipi Calbaizer Marchi +4 more
doaj +1 more source
VenoMS—A Website for the Low Molecular Mass Compounds in Spider Venoms
Metabolites, 2020 Spider venoms are highly complex mixtures. Numerous spider venom metabolites are uniquely found in spider venoms and are of interest concerning their potential use in pharmacology, agriculture, and cosmetics.
Yvonne M. Forster +4 more
doaj +1 more source
Toxins, 2022 Venom compositions include complex mixtures of toxic proteins that evolved to immobilize/dissuade organisms by disrupting biological functions. Venom production is metabolically expensive, and parsimonious use is expected, as suggested by the venom ...
Sean Rayner +7 more
doaj +1 more source
Sphingomyelinase D from Loxosceles laeta Venom Induces the Expression of MMP7 in Human Keratinocytes: Contribution to Dermonecrosis. [PDF]
PLoS ONE, 2016 Envenomation by Loxosceles spider is characterized by the development of dermonecrosis. In previous studies, we have demonstrated that increased expression/secretion of matrix metalloproteinases 2 and 9, induced by Loxosceles intermedia venom Class 2 ...
Mara A Corrêa +4 more
doaj +1 more source
Spider-Venom Peptides as Bioinsecticides [PDF]
Toxins, 2012 Over 10,000 arthropod species are currently considered to be pest organisms. They are estimated to contribute to the destruction of ~14% of the world’s annual crop production and transmit many pathogens. Presently, arthropod pests of agricultural and health significance are controlled predominantly through the use of chemical insecticides ...
Monique J. Windley +5 more
openaire +4 more sources
Venom-gland transcriptomics and venom proteomics of the Tibellus oblongus spider
Scientific Data, 2023 The Tibellus oblongus spider is an active hunter that does not spin webs and remains highly underinvestigated in terms of the venom composition. Here, we describe venom glands transcriptome and venom proteome analysis for unveiling the polypeptide ...
Yuliya Korolkova +7 more
doaj +1 more source
Functional Profiling of the A-Family of Venom Peptides from the Wolf Spider Lycosa shansia
Toxins, 2023 The venoms of spiders from the RTA (retro-lateral tibia apophysis) clade contain diverse short linear peptides (SLPs) that offer a rich source of therapeutic candidates. Many of these peptides have insecticidal, antimicrobial and/or cytolytic activities,
Tim Lüddecke +9 more
semanticscholar +1 more source