Results 51 to 60 of about 132,886 (258)

Recent Advances in Research on Widow Spider Venoms and Toxins

open access: yesToxins, 2015
Widow spiders have received much attention due to the frequently reported human and animal injures caused by them. Elucidation of the molecular composition and action mechanism of the venoms and toxins has vast implications in the treatment of ...
Shuai Yan, Xianchun Wang
doaj   +1 more source

Multitarget nociceptor sensitization by a promiscuous peptide from the venom of the King Baboon spider

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2022
Significance Pain development and discomfort are universal features of spider envenomation, yet severe pain arising from bites by Old World spiders is poorly understood.
Rocio K. Finol-Urdaneta   +19 more
semanticscholar   +1 more source

Spider venom administration impairs glioblastoma growth and modulates immune response in a non-clinical model

open access: yesScientific Reports, 2020
Molecules from animal venoms are promising candidates for the development of new drugs. Previous in vitro studies have shown that the venom of the spider Phoneutria nigriventer (PnV) is a potential source of antineoplastic components with activity in ...
A. Bonfanti   +12 more
semanticscholar   +1 more source

Chromosome‐level genome assembly of the black widow spider Latrodectus elegans illuminates composition and evolution of venom and silk proteins

open access: yesGigaScience, 2022
Background The black widow spider has both extraordinarily neurotoxic venom and three-dimensional cobwebs composed of diverse types of silk. However, a high-quality reference genome for the black widow spider was still unavailable, which hindered deep ...
Zhongkai Wang   +6 more
semanticscholar   +1 more source

Brown Spider (Loxosceles genus) Venom Toxins: Tools for Biological Purposes

open access: yesToxins, 2011
Venomous animals use their venoms as tools for defense or predation. These venoms are complex mixtures, mainly enriched of proteic toxins or peptides with several, and different, biological activities.
Andrea Senff-Ribeiro   +11 more
doaj   +1 more source

Heterophilic antibodies in sera from individuals without loxoscelism cross-react with phospholipase D from the venom of Loxosceles and Sicarius spiders

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2018
Background Loxoscelism is a severe human envenomation caused by Loxosceles spider venom. To the best of our knowledge, no study has evaluated the presence of antibodies against Loxosceles venom in loxoscelism patients without treatment with antivenom ...
Tomás Arán-Sekul   +8 more
doaj   +1 more source

Spider venom peptides as potential drug candidates due to their anticancer and antinociceptive activities

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2019
Spider venoms are known to contain proteins and polypeptides that perform various functions including antimicrobial, neurotoxic, analgesic, cytotoxic, necrotic, and hemagglutinic activities.
Ting Wu   +6 more
semanticscholar   +1 more source

Tying pest insects in knots: the deployment of spider-venom-derived knottins as bioinsecticides.

open access: yesPest Management Science, 2019
Spider venoms are complex chemical arsenals that contain a rich variety of insecticidal toxins. However, the major toxin class in many spider venoms is disulfide-rich peptides known as knottins.
G. King
semanticscholar   +1 more source

Characterisation of protein families in spider digestive fluids and their role in extra-oral digestion

open access: yesBMC Genomics, 2017
Background Spiders are predaceous arthropods that are capable of subduing and consuming relatively large prey items compared to their own body size. For this purpose, spiders have evolved potent venoms to immobilise prey and digestive fluids that break ...
André Walter   +6 more
doaj   +1 more source

Toward a unified understanding of people’s aversion to nature: biophobia

open access: yesFrontiers in Ecology and the Environment, EarlyView.
Human–nature relationships are often framed positively, but research rarely addresses biophobia, the aversion to nature. However, negative relationships with nature are likely to become more widespread following societal and environmental changes, with serious implications for public health and conservation efforts.
Johan Kjellberg Jensen   +2 more
wiley   +1 more source

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