Results 91 to 100 of about 40,476 (180)
Case Report of Combined Central and Peripheral Demyelination: Treated With Ofatumumab
Immunity, Inflammation and Disease, Volume 14, Issue 5, May 2026.ABSTRACT Background and Objectives Combined central and peripheral demyelination (CCPD) is a rare autoimmune‐mediated disorder characterized by demyelination affecting both the central nervous system and peripheral nervous system. The involvement of the CNS typically manifests as longitudinally extensive transverse myelitis and optic neuritis, whereas ...
Lili Liu +4 more
wiley +1 more source
In silico study to predict and characterize of SARS CoV 2 Surface glycoprotein
Vaccine Research, 2020 Introduction: Coronavirus family member SARS- CoV-2 is a current worldwide threat. It enters into the epithelium membrane of respiratory tract with the help of its antigenic spike proteins and cause Coronavirus disease 2019 (COVID -19).
Avnish Kumar, Bhuvnesh Prasad Sharma
doaj
Journal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.ABSTRACT SARS‐CoV‐2 infection is linked to persistent neurological symptoms Post‐Acute Sequelae SARS‐CoV‐2 (neuro‐PASC) and elevated risk of neurodegenerative disease, but molecular events connecting acute viral injury to long‐term CNS dysfunction remain unclear.
Gunjan Bawne +4 more
wiley +1 more source
Nucleotide Sequence of the Gene Encoding the Spike Glycoprotein of Human Coronavirus HCV 229E
Journal of General Virology, 1990 The gene encoding the spike glycoprotein of the human coronavirus HCV 229E has been cloned and sequenced. This analysis predicts an S polypeptide of 1173 amino acids with an Mr of 128,600. The polypeptide has 30 potential N-glycosylation sites. A number of structural features typical of coronavirus S proteins can be recognized, including a signal ...
T, Raabe, B, Schelle-Prinz, S G, Siddell
openaire +2 more sources
SARS‐CoV‐2 Variants and Immune Evasion: Mapping the Future of Vaccine Design
Reviews in Medical Virology, Volume 36, Issue 3, May 2026.ABSTRACT The evolutionary trajectory of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2) has progressed through several distinct phases since its zoonotic emergence, transitioning from initial human adaptation to an era of rapid antigenic drift and complex immune evasion. As of early 2026, the global landscape is dominated by highly evolved
Fatih Uzer +2 more
wiley +1 more source
Molecular Detection of Alpha‐ and Betacoronaviruses in Bats from Afar Region, Ethiopia
Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.Bats are critical reservoirs of coronaviruses, yet gaps remain in understanding coronavirus diversity within bat populations in Eastern Ethiopia. A total of 141 bats were captured: 129 Chaerephon pumilus, 11 Epomophorus labiatus and 1 Mops condylurus. Coronaviruses detected in eight bats.
Bula Mengesha +2 more
wiley +1 more source
Conserved High Free Energy Sites in Human Coronavirus Spike Glycoprotein Backbones
Journal of Computational Biology, 2020 Methods previously developed by the author are applied to uncover several sites of interest in the spike glycoproteins of all known human coronaviruses (hCoVs), including SARS-CoV-2 that causes COVID-19. The sites comprise three-dimensional neighborhoods of peptides characterized by four key properties: (1) they pinpoint regions of high free energy in ...
openaire +2 more sources
Molecular Targets for Diagnostics and Therapeutics of Severe Acute Respiratory Syndrome (SARS-CoV)
Journal of Pharmacy & Pharmaceutical Sciences, 2008 PURPOSE. The large number of deaths in a short period of time due to the spread of severe acute respiratory syndrome (SARS) infection led to the unparalleled collaborative efforts world wide to determine and characterize the new coronavirus (SARS-CoV ...
Mavanur R. Suresh +2 more
doaj +1 more source
Expression and Immunogenicity of the Spike Glycoprotein of Porcine Respiratory Coronavirus Encoded in the E3 Region of Adenovirus [PDF]
, 1995 The full length spike (S) gene of porcine respiratory coronavirus (PRCV) was inserted into the genome of human adenovirus type 5 downstream of the early transcription region 3 promoter. The recombinant virus replicated in cultures of the swine testicle ST cell line and directed the synthesis of S antigen to an amount of approximately 33 micrograms per ...
P, Callebaut, M, Pensaert
openaire +2 more sources
Virus Research, 2002 It is unclear whether respiratory and enteric bovine coronavirus (BoCV) strains are distinctive in biological, antigenic and genetic characteristics. In the present study, we analyzed the nucleotide and amino acid sequence of the S1 subunit of the S glycoprotein, including the cleavage site, of both respiratory (n=5) and enteric (n=3) BoCV isolates ...
Hasoksuz, Mustafa +4 more
openaire +3 more sources