Results 101 to 110 of about 40,476 (180)

Protection from SARS coronavirus conferred by live measles vaccine expressing the spike glycoprotein

Virology, 2014
The recent identification of a novel human coronavirus responsible of a SARS-like illness in the Middle-East a decade after the SARS pandemic, demonstrates that reemergence of a SARS-like coronavirus from an animal reservoir remains a credible threat. Because SARS is contracted by aerosolized contamination of the respiratory tract, a vaccine inducing ...
Escriou, Nicolas, Callendret, Benoît, Lorin, Valérie, Combredet, Chantal, Marianneau, Philippe, Février, Michèle, Tangy, Frédéric   +6 more
openaire   +2 more sources

A conditional-lethal murine coronavirus mutant that fails to incorporate the spike glycoprotein into assembled virions

Virus Research, 1995
The coronavirus spike glycoprotein (S) mediates both the attachment of virus to the host cell receptor and membrane fusion. We describe here the characterization of a temperature-sensitive mutant of the coronavirus mouse hepatitis virus A59 (MHV-A59) having multiple S protein-related defects. The most remarkable of these was that the mutant, designated
Ricard, Cynthia S., Koetzner, Cheri A., Sturman, Lawrence S., Masters, Paul S.   +3 more
openaire   +2 more sources

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Genome-wide bioinformatics analysis of human protease capacity for proteolytic cleavage of the SARS-CoV-2 spike glycoprotein

Microbiology Spectrum
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) primarily enters the cell by binding the virus’s spike (S) glycoprotein to the angiotensin-converting enzyme 2 receptor on the cell surface, followed by proteolytic cleavage by host proteases ...
Evgenii V. Matveev, Gennady V. Ponomarev, Marat D. Kazanov   +2 more
doaj   +1 more source

SARS-CoV-2 spike protein variant binding affinity to an angiotensin-converting enzyme 2 fusion glycoproteins

PLoS ONE, 2022
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causative agent of the Coronavirus disease 2019 (Covid-19) pandemic, continues to evolve and circulate globally.
Alicia M. Matthews, Thomas G. Biel, Uriel Ortega-Rodriguez, Vincent M. Falkowski, Xin Bush, Talia Faison, Hang Xie, Cyrus Agarabi, V. Ashutosh Rao, Tongzhong Ju   +9 more
doaj  

Exploring the Intrinsic Structural Plasticity and Conformational Dynamics of Human Beta Coronavirus Spike Glycoproteins

Journal of Chemical Information and Modeling
The spike (S) glycoprotein of human beta coronaviruses (HCoVs) is central to viral entry, receptor engagement, and immune evasion. Here, we present an in-depth computational analysis of spike conformational dynamics across HCoVs, with a focus on SARS-CoV-2 and its variants.
Yago Ferreira e Silva, Harold Hilarion Fokoue, Paulo Ricardo Batista   +2 more
openaire   +2 more sources

Influence of Mutations on Physicochemical Properties of Spike Proteins from Prototypical SARS-CoV-2 Variants of Concern Detected in Amazonian Countries

Microbiology Research
Since the emergence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the viral spike protein (S) has become a target to describe appropriate epitopes for vaccine development and to carry out epidemiological surveillance, especially ...
Adriana Conceição B. Silva, Carlos Alberto M. Carvalho   +1 more
doaj   +1 more source

SARS-CoV-2 spike-reactive naïve B cells and pre-existing memory B cells contribute to antibody responses in unexposed individuals after vaccination

Frontiers in Immunology
IntroductionSince December 2019, the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus disease 2019 (COVID-19) has presented considerable public health challenges.
Shishan Teng, Shishan Teng, Yabin Hu, Yabin Hu, You Wang, You Wang, Yinggen Tang, Yinggen Tang, Qian Wu, Xingyu Zheng, Xingyu Zheng, Rui Lu, Rui Lu, Dong Pan, Dong Pan, Fen Liu, Fen Liu, Tianyi Xie, Tianyi Xie, Chanfeng Wu, Chanfeng Wu, Yi-Ping Li, Wenpei Liu, Xiaowang Qu   +23 more
doaj   +1 more source

IN-SILICO STUDY OF SILYMARIN AGAINST SPIKE GLYCOPROTEIN OF CORONAVIRUS

International Research Journal of Modernization in Engineering Technology and Science, 2022
openaire   +1 more source