Results 21 to 30 of about 40,476 (180)
Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer [PDF]
Nature, 2016 The tremendous pandemic potential of coronaviruses was demonstrated twice in the past few decades by two global outbreaks of deadly pneumonia. Entry of coronaviruses into cells is mediated by the transmembrane spike glycoprotein S, which forms a trimer carrying receptor-binding and membrane fusion functions.
Walls, Alexandra +7 more
openaire +5 more sources
Multiple regions of the murine coronavirus spike glycoprotein influence neurovirulence [PDF]
Journal of NeuroVirology, 2001 The spike (S) glycoprotein of mouse hepatitis virus (MHV) is a major determinant of neurovirulence. Using targeted recombination we previously demonstrated that the S gene of the highly neurovirulent MHV-4 conferred a dramatic increase in neurovirulence to the mildly neurovirulent MHV-A59.
Phillips, Joanna J +3 more
openaire +4 more sources
Journal of Biomedicine and Translational Research, 2020 Background: The emergence of infectious diseases caused by SARS-CoV-2 has resulted in more than 90,000 infections and 3,000 deaths. The coronavirus spike glycoprotein encourages the entry of SARS-CoV-2 into cells and is the main target of antivirals ...
Taufik Muhammad Fakih +1 more
doaj +1 more source
Mutational heterogeneity in spike glycoproteins of severe acute respiratory syndrome coronavirus 2 [PDF]
3 Biotech, 2021 The novel coronavirus SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) has led to a global crisis by infecting millions of people across the globe eventually causing multiple deaths. The prominent player of the virus has been known as the spike protein which enters the host system and leads to the infection.
Aanchal Mathur +5 more
openaire +2 more sources
The Human Leukocyte Antigen Class II Immunopeptidome of the SARS-CoV-2 Spike Glycoprotein
Cell Reports, 2020 Summary: Precise elucidation of the antigen sequences for T cell immunosurveillance greatly enhances our ability to understand and modulate humoral responses to viral infection or active immunization.
Michael D. Knierman +5 more
doaj +1 more source
Frontiers in Immunology, 2021 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) initiates infection by attachment of the surface-exposed spike glycoprotein to the host cell receptors.
Preeti Vishwakarma +12 more
doaj +1 more source
Cells, 2020 Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the causative agent of the Coronavirus disease (COVID-19) pandemic, has so far resulted in more than 1.1 M deaths and 40 M cases worldwide with no confirmed remedy yet available.
Anastassios C. Papageorgiou +1 more
doaj +1 more source
Heliyon, 2023 The SARS-CoV-2 virus has been identified as the infectious agent that led to the COVID-19 pandemic, which the world has seen very recently. Researchers have linked the SARS-CoV-2 outbreak to bats for the zoonotic spread of the virus to humans ...
Tuhin Das +4 more
doaj +1 more source
Sensitive detection systems for infectious agents in xenotransplantation*
Xenotransplantation, EarlyView., 2020 Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley +1 more source
Primary Structures of Hemagglutinin-esterase and Spike Glycoproteins of Murine Coronavirus DVIM [PDF]
Virus Genes, 1998 Diarrhea virus of infant mice (DVIM) is a member of murine hepatitis viruses (MHVs). The nucleotide sequences of the genes encoding the hemagglutinin-esterase (HE) and the spike (S) glycoproteins from DVIM were determined and compared with those of other MHVs.
Morita, Eiji +5 more
openaire +2 more sources