Results 41 to 50 of about 51,283 (222)

Primary Structures of Hemagglutinin-esterase and Spike Glycoproteins of Murine Coronavirus DVIM [PDF]

Virus Genes, 1998
Diarrhea virus of infant mice (DVIM) is a member of murine hepatitis viruses (MHVs). The nucleotide sequences of the genes encoding the hemagglutinin-esterase (HE) and the spike (S) glycoproteins from DVIM were determined and compared with those of other MHVs.
Morita, Eiji, Ebina, Hirotaka, Muto, Akira, Himeno, Hyouta, Hatakeyama, Koki, Sugiyama, Kazuo   +5 more
openaire   +2 more sources

Missense mutations in spike protein of SARS‐CoV‐2 delta variant contribute to the alteration in viral structure and interaction with hACE2 receptor

Immunity, Inflammation and Disease, 2022
Introduction Many of the global pandemics threaten human existence over the decades among which coronavirus disease (COVID‐19) is the newest exposure circulating worldwide.
Tousif Bin Mahmood, Mohammad Imran Hossan, Shafi Mahmud, Mst. Sharmin Sultana Shimu, Md. Jahidul Alam, Md. Mahfuzur Rahman Bhuyan, Talha Bin Emran   +6 more
doaj   +1 more source

Molecular docking and dynamic simulation of conserved B cell epitope of SARS-CoV-2 glycoprotein Indonesian isolates: an immunoinformatic approach [version 1; peer review: 3 approved]

F1000Research, 2021
Background: An immunoinformatic approach may be useful to investigate the conserved region in the spike glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Indonesia isolates.
Fedik Abdul Rantam, Viol Dhea Kharisma, Christrijogo Sumartono, Jusak Nugraha, Andi Yasmin Wijaya, Helen Susilowati, Suryo Kuncorojakti, Alexander Patera Nugraha   +7 more
doaj   +1 more source

Receptor binding may directly activate the fusion machinery in coronavirus spike glycoproteins [PDF]

, 2021
AbstractSARS-CoV-2, the causative agent of the COVID-19 pandemic, is an enveloped RNA virus. Trimeric spike glycoproteins extend outward from the virion; these class I viral membrane fusion proteins mediate entry of the virus into a host cell and are the dominant antigen for immune response.
Yuzhang Wang, Lucy Fallon, Lauren Raguette, Stephanie Budhan, Kellon Belfon, Darya Stepanenko, Stephanie Helbock, Sarah Varghese, Carlos Simmerling   +8 more
openaire   +1 more source

Canine respiratory coronavirus employs caveolin-1-mediated pathway for internalization to HRT-18G cells [PDF]

, 2018
Canine respiratory coronavirus (CRCoV), identified in 2003, is a member of the Coronaviridae family. The virus is a betacoronavirus and a close relative of human coronavirus OC43 and bovine coronavirus.
A Milewska, A Pratelli, A Quan, Aleksandra Milewska, AM Zaki, Artur Szczepanski, B Hernaez, B Jancekova, BA Mainou, BJ Dille, C Burkard, C Kooi, C Liu, C Liu, D Dutta, DM Blau, E Dietzel, E Girard, E Hamme Van, EJ Bowman, F Samson, G Preta, GA Wudiri, GM Li, GR Ares, H Imhoff, H Lin, H Wang, IC Huang, IM Mackay, J Li, J Schindelin, J Somsel Rodman, JA Mitchell, JK Millet, JL Wang, JP Lim, JR Henley, Judy A. Mitchell, K Erles, K Erles, K Owczarek, K Shirato, K Shirato, Katarzyna Owczarek, Krzysztof Pyrc, KS Choi, L Kleist von, L Pelkmans, LH Wang, LJ Reed, M Marsh, MG Hemida, MJ Geisow, MJ Vincent, O Achour, O Heikkila, P Duckert, P Eifart, P Oh, Q Xu, R Nomura, S Bertram, S Bolte, S Gierer, S Matsuyama, SL Priestnall, TA Hill, VC Chu, X Ren, Y Inoue, Y Phonphok, Z Qian, Z Qinfen, Zbigniew Baster, Zenon Rajfur   +75 more
core   +8 more sources

An optimised method for the production of MERS-CoV spike expressing viral pseudotypes [PDF]

, 2015
The production and use of pseudotyped viral particles is widely established for many viruses, and applications in the fields of serology and vaccine development are manifold.
Carnell, Ferrara, Kutner, Mather, Molesti, Qian, Scott, Temperton, Wang, Zhao, Zufferey, Zufferey   +11 more
core   +2 more sources

Cytokine release syndrome in COVID-19 patients, a new scenario for an old concern. The fragile balance between infections and autoimmunity [PDF]

, 2020
On 7 January 2020, researchers isolated and sequenced in China from patients with severe pneumonitis a novel coronavirus, then called SARS-CoV-2, which rapidly spread worldwide, becoming a global health emergency.
Diamanti, A. P., Lagana, B., Pioli, C., Rosado, M. M., Sesti, G.   +4 more
core   +2 more sources

Murine Coronavirus Spike Glycoprotein [PDF]

, 2001
The mature Coronavirus spike is a large, oligomeric, type I integral membrane glycoprotein that projects about 20 nm from the surface of infected cells and virions. In this extracellular position, the spikes function to bind the cellular receptors extending from opposing membranes.
openaire   +2 more sources

Treatment with Exogenous Trypsin Expands In Vitro Cellular Tropism of the Avian Coronavirus Infectious Bronchitis Virus

Viruses, 2020
The Gammacoronavirus infectious bronchitis virus (IBV) causes a highly contagious and economically important respiratory disease in poultry. In the laboratory, most IBV strains are restricted to replication in ex vivo organ cultures or in ovo and do not ...
Phoebe Stevenson-Leggett, Sarah Keep, Erica Bickerton   +2 more
doaj   +1 more source

Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2. [PDF]

PLoS Pathogens, 2018
The trimeric SARS coronavirus (SARS-CoV) surface spike (S) glycoprotein consisting of three S1-S2 heterodimers binds the cellular receptor angiotensin-converting enzyme 2 (ACE2) and mediates fusion of the viral and cellular membranes through a pre- to ...
Wenfei Song, Miao Gui, Xinquan Wang, Ye Xiang   +3 more
doaj   +1 more source