Results 51 to 60 of about 51,283 (222)

Carbohydrate Ligands for COVID-19 Spike Proteins

Viruses, 2022
An outbreak of SARS-CoV-2 coronavirus (COVID-19) first detected in Wuhan, China, has created a public health emergency all over the world. The pandemic has caused more than 340 million confirmed cases and 5.57 million deaths as of 23 January 2022 ...
Yung-Kuo Lee, Wen-Chiu Chang, Ekambaranellore Prakash, Yu-Ju Peng, Zhi-Jay Tu, Chun-Hung Lin, Pang-Hung Hsu, Chuan-Fa Chang   +7 more
doaj   +1 more source

Ezrin interacts with the SARS coronavirus spike protein and restrains infection at the entry stage [PDF]

, 2012
© 2012 Millet et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Chen, A Roumier, AG Wise, B Fievet, B Nal, B Treanor, B Treanor, BJ Bosch, BT Fievet, Béatrice Nal, C Drosten, CE McBride, CE McBride, Chung-Yan Cheung, CM Finnerty, CM Petit, CM Petit, CY Cheung, D Cavanagh, E Formstecher, E Lontok, François Kien, G Simmons, G Simmons, H Ma, Hiu-Lan Leung, HS Kim, Huiying Li, I Nefkens, IC Huang, J Haedicke, Jean Kaoru Millet, JK Locker, Joseph S. Malik Peiris, JP Nuesch, JP Richard, JS Peiris, K Hamada, K Hamada, KT Teoh, L Naldini, M Algrain, M Barrero-Villar, M Baumgartner, M Fromont-Racine, M Jaume, Martial Jaume, MH Naghavi, MJ Moore, MW Howard, N Gupta, P Wang, PC Woo, PC Woo, R Lasserre, R Zufferey, Ralf Marius Altmeyer, RG Fehon, RI Connor, Roberto Bruzzone, S Charrin, S Yonemura, SF Altschul, SK Lau, Stefan Pöhlmann, T Crepaldi, T Giroglou, T Kuiken, T Mori, TG Ksiazek, V Das, W Li, Wing-Lim Chan, WJ Smith, Y Kubo, YJ Zhang, YL Siu, Yu-Lam Siu, YW Kam, YW Kam   +79 more
core   +6 more sources

Immunogenicity of a recombinant coronavirus spike glycoprotein expressed in transgenic plants [PDF]

Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz, 2000
Recently, it has been demonstrated that plants offer the possibility of producing low cost subunit vaccines that can be either parenterally or orally administered. Here we review data we obtained on the immunological response elicited by two recombinant versions of the glycoprotein S from the swine transmissible gastroenteritis coronavirus (TGEV ...
Escribano, J.M., Borca, M.V.
openaire   +1 more source

Rational design of a hybrid peptide against severe acute respiratory syndrome coronavirus 2 using melittin and angiotensin-converting enzyme 2 as pharmaceutical agents

Advanced Biomedical Research, 2022
Background: Management of severe acute respiratory syndrome coronavirus 2 in humans depends on the availability of vaccines or effective drugs. Studies have shown that angiotensin-converting enzyme 2 (ACE2) is responsible for binding the viral spike ...
Ramin Farhoudi, Mohammad Taheri, Minoo Soltani, Ramin Mazaheri Nezhad Fard, Golshid Javdani Shahedin, Sedigheh Nabian   +5 more
doaj   +1 more source

Spike S1 domain interactome in non-pulmonary systems: A role beyond the receptor recognition

Frontiers in Molecular Biosciences, 2022
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes Coronavirus Disease 2019 (COVID-19), which, since 2019 in China, has rapidly become a worldwide pandemic.
Ilaria Iacobucci, Ilaria Iacobucci, Vittoria Monaco, Vittoria Monaco, Luisa Canè, Luisa Canè, Francesca Bibbò, Francesca Bibbò, Valentina Cioffi, Flora Cozzolino, Flora Cozzolino, Alfredo Guarino, Massimo Zollo, Massimo Zollo, Maria Monti, Maria Monti   +15 more
doaj   +1 more source

Genome Composition and Divergence of the Novel Coronavirus (2019-nCoV) Originating in China. [PDF]

, 2020
An in-depth annotation of the newly discovered coronavirus (2019-nCoV) genome has revealed differences between 2019-nCoV and severe acute respiratory syndrome (SARS) or SARS-like coronaviruses.
Cheng, Genhong, Ding, Xiao, Huang, Baoying, Jiang, Taijiao, Meng, Jing, Niu, Peihua, Peng, Yousong, Quan, Lijun, Sheng, Jie, Tan, Wenjie, Wang, Jiangyuan, Wang, Xianyue, Wu, Aiping, Xia, Zanxian, Zhang, Zheng, Zhu, Zhaozhong   +15 more
core  

The V5A13.1 envelope glycoprotein deletion mutant of mouse hepatitis virus type-4 is neuroattenuated by its reduced rate of spread in the central nervous system. [PDF]

, 1992
Following intracerebral inoculation of adult Balb/c Byj mice, the MHV-4 strain of mouse hepatitis virus (MHV) had an LD50 of less than 0.1 PFU, whereas its monoclonal antibody resistant variant V5A13.1 had an LD50 of 10(4.2) PFU.
Bloom, F, Buchmeier, MJ, Fazakerley, JK, Parker, SE   +3 more
core   +1 more source

Does Early Childhood Vaccination Protect Against COVID-19?

Frontiers in Molecular Biosciences, 2020
The coronavirus disease 2019 (COVID-19) is an on-going pandemic caused by the SARS-coronavirus-2 (SARS-CoV-2) which targets the respiratory system of humans.
Karzan R. Sidiq, Karzan R. Sidiq, Dana Khdr Sabir, Shakhawan M. Ali, Rimantas Kodzius, Rimantas Kodzius   +5 more
doaj   +1 more source

SARS-CoV-2 Vaccines Based on the Spike Glycoprotein and Implications of New Viral Variants

Frontiers in Immunology, 2021
Coronavirus 19 Disease (COVID-19) originating in the province of Wuhan, China in 2019, is caused by the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), whose infection in humans causes mild or severe clinical manifestations that mainly
Daniel Martínez-Flores, Jesús Zepeda-Cervantes, Jesús Zepeda-Cervantes, Adolfo Cruz-Reséndiz, Sergio Aguirre-Sampieri, Alicia Sampieri, Luis Vaca   +6 more
doaj   +1 more source

COVID-19 and iron dysregulation: distant sequence similarity between hepcidin and the novel coronavirus spike glycoprotein

Biology Direct, 2020
The spike glycoprotein of the SARS-CoV-2 virus, which causes COVID-19, has attracted attention for its vaccine potential and binding capacity to host cell surface receptors. Much of this research focus has centered on the ectodomain of the spike protein.
Sepehr Ehsani
doaj   +1 more source