Results 1 to 10 of about 39,110 (117)
Frontiers in Cell and Developmental Biology, 2021 The nuclear mitotic apparatus (NuMA) protein is well conserved in vertebrates, and dynamically changes its subcellular localization from the interphase nucleus to the mitotic/meiotic spindle poles and the mitotic cell cortex.
Tomomi Kiyomitsu
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The evolutionary history of human spindle genes includes back-and-forth gene flow with Neandertals
eLife, 2022 Proteins associated with the spindle apparatus, a cytoskeletal structure that ensures the proper segregation of chromosomes during cell division, experienced an unusual number of amino acid substitutions in modern humans after the split from the ...
Stéphane Peyrégne +3 more
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eLife, 2022 During cell division, the spindle generates force to move chromosomes. In mammals, microtubule bundles called kinetochore-fibers (k-fibers) attach to and segregate chromosomes. To do so, k-fibers must be robustly anchored to the dynamic spindle.
Pooja Suresh +3 more
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eLife, 2022 While centrosomes organize spindle poles during mitosis, oocyte meiosis can occur in their absence. Spindles in human oocytes frequently fail to maintain bipolarity and consequently undergo chromosome segregation errors, making it important to understand
Gabriel Cavin-Meza +2 more
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Scaling Laws for Mitotic Chromosomes
Frontiers in Cell and Developmental Biology, 2021 During mitosis in higher eukaryotes, each chromosome condenses into a pair of rod-shaped chromatids. This process is co-regulated by the activity of several gene families, and the underlying biophysics remains poorly understood.
Eric M. Kramer +2 more
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eLife, 2020 Asymmetric astral microtubule organization drives the polarized orientation of the S. cerevisiae mitotic spindle and primes the invariant inheritance of the old spindle pole body (SPB, the yeast centrosome) by the bud.
Marco Geymonat +6 more
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İğsi Hücreli Lipomların Cerrahi Tedavisi Sonrası Klinik Sonuçlar
Düzce Tıp Fakültesi Dergisi, 2021 Aim: Spindle cell lipoma is a rare tumor. Although located subcutaneously, they are localized in the posterior neck, shoulder, and lumbar regions. It can radiologically mimic liposarcoma. It is important to differentiate spindle cell lipoma from atypical
Muhammed Beşir Öztürk +4 more
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Multiple Roles of PLK1 in Mitosis and Meiosis
Cells, 2023 Cells are equipped with a diverse network of signaling and regulatory proteins that function as cell cycle regulators and checkpoint proteins to ensure the proper progression of cell division. A key regulator of cell division is polo-like kinase 1 (PLK1),
Jaroslav Kalous, Daria Aleshkina
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Animals, 2023 C-type natriuretic peptide (CNP) is a peptide molecule naturally found in follicles and can be used to extend meiotic resumption and enhance the potential for oocytes to develop.
Rui Xu +9 more
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CtIP Regulates Mitotic Spindle Assembly by Modulating the TPX2-Aurora A Signaling Axis
Cells, 2022 CtBP-interacting protein (CtIP) plays a critical role in controlling the homologous recombination-mediated DNA double-stranded break (DSB) repair pathway through DNA end resection, and recent studies suggest that it also plays a role in mitosis. However,
Wonkyung Oh +4 more
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