Results 11 to 20 of about 562,858 (399)

The Spindle Assembly Checkpoint [PDF]

Current Biology, 2012
During mitosis and meiosis, the spindle assembly checkpoint acts to maintain genome stability by delaying cell division until accurate chromosome segregation can be guaranteed. Accuracy requires that chromosomes become correctly attached to the microtubule spindle apparatus via their kinetochores.
Pablo Lara-Gonzalez, Frederick G. Westhorpe, Stephen S. Taylor   +2 more
semanticscholar   +3 more sources

Mechanism of spindle pole organization and instability in human oocytes

Science, 2022
Human oocytes are prone to assembling meiotic spindles with unstable poles, which can favor aneuploidy in human eggs. The underlying causes of spindle instability are unknown.
C. So, Katerina Menelaou, Julia Uraji, Katarina Harasimov, A. Steyer, K. B. Seres, J. Bucevičius, G. Lukinavičius, W. Möbius, Claus Sibold, A. Tandler-Schneider, H. Eckel, Rüdiger Moltrecht, M. Blayney, K. Elder, M. Schuh   +15 more
semanticscholar   +1 more source

The spindle checkpoint [PDF]

Journal of Cell Science, 2006
Every mitosis, replicated chromosomes must be accurately segregated into each daughter cell. Pairs of sister chromatids attach to the bipolar mitotic spindle during prometaphase, they are aligned at metaphase, then sisters separate and are pulled to opposite poles during anaphase.
Karen M, May, Kevin G, Hardwick
openaire   +2 more sources

Endogenous memory reactivation during sleep in humans is clocked by slow oscillation-spindle complexes

Nature Communications, 2020
Sleep is thought to support memory consolidation via reactivation of prior experiences, with particular electrophysiological sleep signatures (slow oscillations (SOs) and sleep spindles) gating the information flow between relevant brain areas.
T. Schreiner, M. Petzka, T. Staudigl, B. Staresina   +3 more
semanticscholar   +1 more source

Modeling and mechanical perturbations reveal how spatially regulated anchorage gives rise to spatially distinct mechanics across the mammalian spindle

eLife, 2022
During cell division, the spindle generates force to move chromosomes. In mammals, microtubule bundles called kinetochore-fibers (k-fibers) attach to and segregate chromosomes. To do so, k-fibers must be robustly anchored to the dynamic spindle.
Pooja Suresh, Vahe Galstyan, Rob Phillips, Sophie Dumont   +3 more
doaj   +1 more source

Sleep spindles [PDF]

Current Biology, 2018
Schönauer and Pöhlchen introduce the reader to sleep spindles, brain oscillations that occur during nREM sleep that are thought to function in the stabilization of memories.
Schönauer, Monika, Pöhlchen, Dorothee
openaire   +3 more sources

DSK1, a novel kinesin-related protein from the diatom Cylindrotheca fusiformis that is involved in anaphase spindle elongation. [PDF]

, 1996
We have identified an 80-kD protein that is involved in mitotic spindle elongation in the diatom Cylindrotheca fusiformis. DSK1 (Diatom Spindle Kinesin 1) was isolated using a peptide antibody raised against a conserved region in the motor domain of the ...
Brady, B, CANDE, W. Zacheus, Foss, M, Wein, H   +3 more
core   +2 more sources

An investigation into reducing the spindle acceleration energy consumption of machine tools [PDF]

, 2016
Machine tools are widely used in the manufacturing industry, and consume large amount of energy. Spindle acceleration appears frequently while machine tools are working. It produces power peak which is highly energy intensive. As a result, a considerable
Jia, Shun, Liu, Ying, Lv, Jingxiang, Tang, Renzhong, Tang, Wangchujun, Zhang, Yingfeng   +5 more
core   +2 more sources

On the stability of high-speed milling with spindle speed variation [PDF]

, 2010
Spindle speed variation is a well-known technique to suppress regenerative machine tool vibrations, but it is usually considered to be effective only for low spindle speeds.
BP Mann, E Al-Regib, E Budak, E Solis, F Yang, Gilles Dessein, Grégoire Peigné, GS Duncan, H Paris, H Zhang, J Tlusty, J Tlusty, JS Sexton, JS Sexton, JS Sexton, Lionel Arnaud, M Zatarain, MA Davies, ML Campomanes, ND Sims, PV Bayly, R Radulescu, RPH Faassen, S Jayaram, S Sastry, S Seguy, S Seguy, S Smith, SA Tobias, SC Lin, SD Merdol, Sébastien Seguy, T Insperger, T Insperger, T Insperger, T Insperger, T Surmann, T Takemura, Tamás Insperger, TC Tsao, XH Long, Y Altintas, Y Altintas, Y Altintas   +43 more
core   +4 more sources

Reduction of the influence on machining surface caused by tool non-repeatable run-out of rolling bearing spindle for machine tools (Improvement of machining surface quality with an excitation system)

Nihon Kikai Gakkai ronbunshu, 2021
In recent years, the demands for mirror finishing by cutting have increased, because the surface quality requirement in die and mold has become severer. In order to realize mirror surface finish by cutting, it is necessary to reduce the influence of tool
Yuta SHOWA, Hayato YOSHIOKA
doaj   +1 more source