Results 11 to 20 of about 412,161 (357)
New Journal of Physics, 2017 Spindles are self-organized microtubule-based structures that segregate chromosomes during cell division. The mass of the spindle is controlled by the balance between microtubule turnover and nucleation. The mechanisms that control the spatial regulation
Foster, Peter J. +5 more
core +2 more sources
Journal of High Energy Physics, 2022 Abstract In the context of holography, we analyse aspects of supersymmetric geometries based on two-dimensional orbifolds known as spindles. By analysing spinc spinors on a spindle with an azimuthal rotation symmetry we show that under rather general conditions there are just two possibilities, called the ‘twist’ and the ‘anti ...
Pietro Ferrero +2 more
openaire +6 more sources
CtIP Regulates Mitotic Spindle Assembly by Modulating the TPX2-Aurora A Signaling Axis
Cells, 2022 CtBP-interacting protein (CtIP) plays a critical role in controlling the homologous recombination-mediated DNA double-stranded break (DSB) repair pathway through DNA end resection, and recent studies suggest that it also plays a role in mitosis. However,
Wonkyung Oh +4 more
doaj +1 more source
İğsi Hücreli Lipomların Cerrahi Tedavisi Sonrası Klinik Sonuçlar
Düzce Tıp Fakültesi Dergisi, 2021 Aim: Spindle cell lipoma is a rare tumor. Although located subcutaneously, they are localized in the posterior neck, shoulder, and lumbar regions. It can radiologically mimic liposarcoma. It is important to differentiate spindle cell lipoma from atypical
Muhammed Beşir Öztürk +4 more
doaj +1 more source
Multiple Roles of PLK1 in Mitosis and Meiosis
Cells, 2023 Cells are equipped with a diverse network of signaling and regulatory proteins that function as cell cycle regulators and checkpoint proteins to ensure the proper progression of cell division. A key regulator of cell division is polo-like kinase 1 (PLK1),
Jaroslav Kalous, Daria Aleshkina
doaj +1 more source
Animals, 2023 C-type natriuretic peptide (CNP) is a peptide molecule naturally found in follicles and can be used to extend meiotic resumption and enhance the potential for oocytes to develop.
Rui Xu +9 more
doaj +1 more source
Scaling Laws for Mitotic Chromosomes
Frontiers in Cell and Developmental Biology, 2021 During mitosis in higher eukaryotes, each chromosome condenses into a pair of rod-shaped chromatids. This process is co-regulated by the activity of several gene families, and the underlying biophysics remains poorly understood.
Eric M. Kramer +2 more
doaj +1 more source
eLife, 2022 While centrosomes organize spindle poles during mitosis, oocyte meiosis can occur in their absence. Spindles in human oocytes frequently fail to maintain bipolarity and consequently undergo chromosome segregation errors, making it important to understand
Gabriel Cavin-Meza +2 more
doaj +1 more source
Journal of Cell Science, 2006 Every mitosis, replicated chromosomes must be accurately segregated into each daughter cell. Pairs of sister chromatids attach to the bipolar mitotic spindle during prometaphase, they are aligned at metaphase, then sisters separate and are pulled to opposite poles during anaphase.
Kevin G. Hardwick, Karen M. May
openaire +3 more sources
Mechanobiology of the Mitotic Spindle [PDF]
Developmental Cell, 2021 The mitotic spindle is a microtubule-based assembly that separates the chromosomes during cell division. As the spindle is basically a mechanical micro machine, the understanding of its functioning is constantly motivating the development of experimental approaches based on mechanical perturbations, which are complementary to and work together with the
Pavin, Nenad, Tolić, Iva M.
openaire +6 more sources