Results 41 to 50 of about 437,835 (354)
Open Biology, 2023 In somatic cells, mitotic transcription of major satellite non-coding RNAs is tightly regulated and essential for heterochromatin formation and the maintenance of genome integrity.
Claudia Baumann +3 more
doaj +1 more source
Study on the 2D Equivalent Simulation Model of Bearing and Spindle for Precision Machine Tools
Machines, 2023 Precision spindle and bearings are the key components in precision machine tools. These structures greatly affect the machining accuracy and service life of the machine tools.
Shijun Xiu +4 more
doaj +1 more source
Non-REM Sleep Characteristics Predict Early Cognitive Impairment in an Aging Population
Frontiers in Neurology, 2019 Objective: Recent research suggests that sleep disorders or changes in sleep stages or EEG waveform precede over time the onset of the clinical signs of pathological cognitive impairment (e.g., Alzheimer's disease).
Jacques Taillard +18 more
doaj +1 more source
Structural Organization and Function of the Golgi Ribbon During Cell Division
Frontiers in Cell and Developmental Biology, 2022 The Golgi complex has a central role in the secretory traffic. In vertebrate cells it is generally organized in polarized stacks of cisternae that are laterally connected by membranous tubules, forming a structure known as Golgi ribbon.
Inmaculada Ayala, Antonino Colanzi
doaj +1 more source
Spindle configurations of skew lines
, 2004 We prove a conjecture of Crapo and Penne which characterizes isotopy classes of skew configurations with spindle-structure. We use this result in order to define an invariant, spindle-genus, for spindle-configurations.
Borobia +11 more
core +2 more sources
Dynactin-dependent cortical dynein and spherical spindle shape correlate temporally with meiotic spindle rotation in Caenorhabditis elegans. [PDF]
, 2015 Oocyte meiotic spindles orient with one pole juxtaposed to the cortex to facilitate extrusion of chromosomes into polar bodies. In Caenorhabditis elegans, these acentriolar spindles initially orient parallel to the cortex and then rotate to the ...
Andaya, Armann +9 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Logspace computations for Garside groups of spindle type [PDF]
, 2013 M. Picantin introduced the notion of Garside groups of spindle type, generalizing the 3-strand braid group. We show that, for linear Garside groups of spindle type, a normal form and a solution to the conjugacy problem are logspace computable. For linear
Elder, Murray, Kalka, Arkadius
core
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source