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Association of mitochondria with spindle poles facilitates spindle alignment [PDF]
Current Biology, 2008 In all eukaryotic cells, correct segregation of the genetic material during cell division requires proper positioning and alignment of the mitotic spindle with respect to the cell division plane. In the fission yeastSchizosaccharomyces pombe, the spindle is aligned by interphase microtubules during early mitosis , and by astral microtubules and cell ...
Iva Marija Tolić-Norrelykke +1 more
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NuMA recruits dynein activity to microtubule minus-ends at mitosis
eLife, 2017 To build the spindle at mitosis, motors exert spatially regulated forces on microtubules. We know that dynein pulls on mammalian spindle microtubule minus-ends, and this localized activity at ends is predicted to allow dynein to cluster microtubules into
Christina L Hueschen +3 more
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Practical Estimation of Machine Tool Spindle Dynamics for Maintenance Decision Making
Applied SciencesCondition-based maintenance of a machine tool spindle unit is known to reduce the total cost of operation in a manufacturing environment. However, standard vibration monitoring thresholds, which are based only on average vibration energy levels, do not ...
Patrick Chin +2 more
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Live cell imaging of meiosis in Arabidopsis thaliana
eLife, 2019 To follow the dynamics of meiosis in the model plant Arabidopsis, we have established a live cell imaging setup to observe male meiocytes. Our method is based on the concomitant visualization of microtubules (MTs) and a meiotic cohesin subunit that ...
Maria A Prusicki +8 more
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eLife, 2022 During anaphase B, molecular motors slide interpolar microtubules to elongate the mitotic spindle, contributing to the separation of chromosomes. However, sliding of antiparallel microtubules reduces their overlap, which may lead to spindle breakage ...
Manuel Lera-Ramirez +2 more
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The Spindle Assembly Checkpoint [PDF]
Current Biology, 2012 During mitosis and meiosis, the spindle assembly checkpoint acts to maintain genome stability by delaying cell division until accurate chromosome segregation can be guaranteed. Accuracy requires that chromosomes become correctly attached to the microtubule spindle apparatus via their kinetochores.
Lara-Gonzalez, Pablo +2 more
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PREDICTION THE EVOLUTION OF TEMPERATURE AND VIBRATIONS ON SPINDLE USING ARTIFICIAL NEURAL NETWORKS AND FUZZY LOGIC [PDF]
Annals: Series on engineering sciences (Academy of Romanian Scientists), 2016 Simulation spindle behavior in terms of temperature and vibration at higher speeds is more economical and more secure (avoid undesirable mechanical events) than testing practice.
Daniel Petru GHENCEA +2 more
doaj
Animals, 2023 F-actin is of critical importance in oocyte meiotic maturation. Actin assembly and its dynamics are mainly regulated by actin nucleation factors. The actin-related protein complex 2/3 (Arp2/3) is responsible for the organization of F-actin filaments ...
Meng-Hao Pan +11 more
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HIM-10 is required for kinetochore structure and function on Caenorhabditis elegans holocentric chromosomes. [PDF]
, 2001 Macromolecular structures called kinetochores attach and move chromosomes within the spindle during chromosome segregation. Using electron microscopy, we identified a structure on the holocentric mitotic and meiotic chromosomes of Caenorhabditis elegans ...
Albertson +33 more
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SciPost PhysicsWe study the spindle compactification of families of AdS_55 consistent truncations corresponding to M5 branes wrapped on complex curves in Calabi-Yau three-folds. From the AdS/CFT correspondence these models are dual to \mathcal{N}=1𝒩=1 SCFTs obtained by gluing of T_NTN blocks.
Amariti, Antonio +4 more
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