Results 41 to 50 of about 542,273 (348)

The Development of a Monitoring System Using a Wireless and Powerless Sensing Node Deployed Inside a Spindle

Sensors, 2011
Installation of a Wireless and Powerless Sensing Node (WPSN) inside a spindle enables the direct transmission of monitoring signals through a metal case of a certain thickness instead of the traditional method of using connecting cables.
Da-Sheng Lee, Liang-Cheng Chang
doaj   +1 more source

Dynactin-dependent cortical dynein and spherical spindle shape correlate temporally with meiotic spindle rotation in Caenorhabditis elegans. [PDF]

, 2015
Oocyte meiotic spindles orient with one pole juxtaposed to the cortex to facilitate extrusion of chromosomes into polar bodies. In Caenorhabditis elegans, these acentriolar spindles initially orient parallel to the cortex and then rotate to the ...
Andaya, Armann, Cortes, Daniel B, Crowder, Marina E, Flynn, Jonathan R, Kuehnert, Paul A, Leary, Julie A, McNally, Francis J, McNally, Karen P, Panzica, Michelle T, Price, Kari L   +9 more
core   +1 more source

Dynein–Dynactin–NuMA clusters generate cortical spindle-pulling forces as a multi-arm ensemble

eLife, 2018
To position the mitotic spindle within the cell, dynamic plus ends of astral microtubules are pulled by membrane-associated cortical force-generating machinery.
Masako Okumura, Toyoaki Natsume, Masato T. Kanemaki, Tomomi Kiyomitsu   +3 more
semanticscholar   +1 more source

The spindle checkpoint [PDF]

Journal of Cell Science, 2006
Every mitosis, replicated chromosomes must be accurately segregated into each daughter cell. Pairs of sister chromatids attach to the bipolar mitotic spindle during prometaphase, they are aligned at metaphase, then sisters separate and are pulled to opposite poles during anaphase.
Karen M, May, Kevin G, Hardwick
openaire   +2 more sources

Kinesins relocalize the chromosomal passenger complex to the midzone for spindle disassembly. [PDF]

, 2018
Mitotic spindle disassembly after chromosome separation is as important as spindle assembly, yet the molecular mechanisms for spindle disassembly are unclear.
Avunie-Masala, Buvelot, Cheeseman, Chen, Cleary, Cormier, Cottingham, David G. Drubin, Foiani, Fridman, Georjana Barnes, Gruneberg, Hoyt, Hoyt, Hsu, Itziar Ibarlucea-Benitez, Jaqaman, Kang, Khmelinskii, Kotwaliwale, Longtine, Luke S. Ferro, Morawska, Movshovich, Murata-Hori, Nakajima, Nakajima, Nicholas, Nishimura, Norden, Petersen, Reck-Peterson, Saunders, Saunders, Shannon, Straight, Tarantino, Thomas, Varga, Woodruff, Woodruff, Xing, Zhang, Zimniak   +43 more
core   +1 more source

The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore–microtubule attachment and in maintaining the spindle assembly checkpoint

Journal of Cell Biology, 2003
The proper segregation of sister chromatids in mitosis depends on bipolar attachment of all chromosomes to the mitotic spindle. We have identified the small molecule Hesperadin as an inhibitor of chromosome alignment and segregation.
Silke Hauf, R. Cole, S. LaTerra, C. Zimmer, G. Schnapp, Rainer Walter, A. Heckel, Jacques van Meel, C. Rieder, J. Peters   +9 more
semanticscholar   +1 more source

Spindle pole bodies [PDF]

Current Biology, 2013
What is a spindle pole body? The spindle pole body (SPB) or duplication plaque of fungi is the functional equivalent of the centrosome in higher eukaryotes. SPBs serve as microtubule organizing centres (MTOCs), sites where microtubules (MTs) are assembled from tubulin subunits. In contrast to centrosomes, SPBs do not contain centrioles.
Seybold, Christian, Schiebel, Elmar
openaire   +2 more sources

NuMA recruits dynein activity to microtubule minus-ends at mitosis

eLife, 2017
To build the spindle at mitosis, motors exert spatially regulated forces on microtubules. We know that dynein pulls on mammalian spindle microtubule minus-ends, and this localized activity at ends is predicted to allow dynein to cluster microtubules into
Christina L Hueschen, Samuel J Kenny, Ke Xu, Sophie Dumont   +3 more
doaj   +1 more source

A novel chromosome segregation mechanism during female meiosis. [PDF]

, 2016
In a wide range of eukaryotes, chromosome segregation occurs through anaphase A, in which chromosomes move toward stationary spindle poles, anaphase B, in which chromosomes move at the same velocity as outwardly moving spindle poles, or both. In contrast,
Cortes, Daniel B, Kim, Taekyung, McNally, Francis J, McNally, Karen Perry, Panzica, Michelle T   +4 more
core   +1 more source

Practical Estimation of Machine Tool Spindle Dynamics for Maintenance Decision Making

Applied Sciences
Condition-based maintenance of a machine tool spindle unit is known to reduce the total cost of operation in a manufacturing environment. However, standard vibration monitoring thresholds, which are based only on average vibration energy levels, do not ...
Patrick Chin, Jose M. DePavia, Stephen C. Veldhuis   +2 more
doaj   +1 more source