Results 141 to 150 of about 959,308 (179)

Identifying the Intergenic ALK Fusion LOC388942‐ALK as a Driver of Non–Small Cell Lung Cancer

open access: yesMedComm, Volume 6, Issue 4, April 2025.
Intergenic breakpoint fusions are generally nonfunctional due to the lack of chimeric full‐coding transcripts. However, in this study we demonstrate an intergenic fusions LOC388942‐ALK (LA) drives oncogenesis through accelerated tumor growth (in vitro/vivo) and alectinib resistance.
Xiaoqian Zhai   +11 more
wiley   +1 more source

Anti‐Inflammatory Treatment of Subarachnoid Hemorrhage by Self‐Assembled Silymarin Nanoparticles

open access: yesSmall Science, Volume 5, Issue 4, April 2025.
Herein, nanoparticles self‐assembled from silymarin have been developed and they are applied in the treatment of neuroinflammation following subarachnoid hemorrhage. The findings reveal that these silymarin nanoparticles can inhibit neuroinflammation through the stimulator of interferon gene/interferon regulatory factor 3 pathway.
Yong Li   +3 more
wiley   +1 more source

Micropillars in Cell Mechanobiology: Design, Fabrication, Characterization, and Biosensing Applications

open access: yesSmall Science, Volume 5, Issue 4, April 2025.
In this article, the pivotal role of micropillars in cell mechanobiology is explored, detailing their design, fabrication, and characterization. Novel applications in biosensing are highlighted, emphasizing their ability to modulate cellular environments and facilitate mechano‐stimulation.
Prabuddha De Saram   +3 more
wiley   +1 more source

Interaction of casein kinase 1 delta (CK1delta) with post-Golgi structures, microtubules and the spindle apparatus.

European Journal of Cell Biology, 2000
Members of the casein kinase 1 family of serine/threonine kinases are highly conserved from yeast to mammals and seem to play an important role in vesicular trafficking, DNA repair, cell cycle progression and cytokinesis.
Lars Behrend   +6 more
semanticscholar   +1 more source

THE MITOTIC SPINDLE APPARATUS OF NEUROSPORA CRASSA

, 1971
Electron microscopic studies of the sl-327 mutant of Neurospora crassa reveal that somatic nuclear division in hyphlet somatic cells involves a definite spindle apparatus consisting of spindle microtubules terminating at specific loci on the external ...
W. V. Winkle, J. Biesele, R. P. Wagner
semanticscholar   +1 more source

Evaluation of the spindle apparatus of in-vitro matured human oocytes following cryopreservation.

Human Reproduction, 1995
The present study was conducted to determine if the cryopreservation of immature human oocytes has a deleterious effect on the meiotic spindle following maturation in vitro. Oocytes were obtained in excess from in-vitro fertilization patients and divided
S. Baka   +5 more
semanticscholar   +1 more source

Mitotic spindle damage induced by 3,4-dichloroaniline in V79 Chinese hamster cells examined by differential staining of the spindle apparatus and chromosomes.

Mutagenesis, 1990
3,4-Dichloroaniline (3,4-DCA), an intermediate in various chemical syntheses, has been detected as an environmental contaminant in surface waters and in the effluents from dye manufacturing plants.
K. Salassidis, M. Bauchinger
semanticscholar   +1 more source

Simultaneous staining of the spindle apparatus and constitutive heterochromatin.

Stain Technology, 1974
In nonhypotonically treated mitoses from tissue cultures grown on cover glasses, the constitutive heterochromatin as well as the spindle apparatus can be stained by a Giemsa technique for demonstrating repetitive DNA.
F. Pera
semanticscholar   +1 more source

Mechanics of the spindle apparatus.

Seminars in Cell and Developmental Biology, 2020
E. Nazockdast, S. Redemann
semanticscholar   +1 more source

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