Results 71 to 80 of about 995,356 (273)
eLife, 2023 WDR62 is a spindle pole-associated scaffold protein with pleiotropic functions. Recessive mutations in WDR62 cause structural brain abnormalities and account for the second most common cause of autosomal recessive primary microcephaly (MCPH), indicating ...
Claudia Dell'Amico +9 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Despite significant efforts in developing novel biomaterials to regenerate tissue, only a few of them have successfully reached clinical use. It has become clear that the next generation of biomaterials must be multifunctional. Smart biomaterials can respond to environmental or external stimuli, interact in a spatial‐temporal manner, and trigger ...
Sonya Ghanavati +12 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.This work presents a novel, dynamically perfused, configurable microfluidic system for epidermis‐only (E and full‐thickness skin (FT SoC) growth, emulating human skin structure and barrier function. Upon TiO2 nanoparticle exposure, the system reveals compromised barrier integrity, reduced metabolic activity, increased permeability, and chemokine‐driven
Samantha Costa +7 more
wiley +1 more source
Progressive Insights into 3D Bioprinting for Corneal Tissue Restoration
Advanced Healthcare Materials, EarlyView.This review explores the potential of 3D bioprinting to replicate the complex structure and function of the human cornea. It highlights key advances in bioink development, printing modalities, and in vivo performance, while addressing current challenges and emerging strategies. The review emphasizes bioprinting's promise to overcome donor shortages and
Ilayda Namli +6 more
wiley +1 more source
Polyglutamylated Tubulin Binding Protein C1orf96/CSAP Is Involved in Microtubule Stabilization in Mitotic Spindles. [PDF]
PLoS ONE, 2015 The centrosome-associated C1orf96/Centriole, Cilia and Spindle-Associated Protein (CSAP) targets polyglutamylated tubulin in mitotic microtubules (MTs).
Shinya Ohta +3 more
doaj +1 more source
Advanced Materials, EarlyView.The Muscle–tendon complex (MTC)‐inspired Liquid crystal elastomer (LCE) artificial muscle integrates actuation (efferent) and proprioceptive sensing (afferent) by combining contractile nematic and elastic isotropic LCEs within a single soft structure. Embedded liquid metal channels enable simultaneous Joule heating and real‐time sensing of length and ...
Jiyeon Cho +6 more
wiley +1 more source
A commercial ARHGEF17/TEM4 antibody cross-reacts with Nuclear Mitotic Apparatus protein 1 (NuMA).
PLoS ONE, 2022 The Rho family Guanine nucleotide exchange factor (GEF) ARHGEF17 (also known as TEM4) is a large protein with only 3 annotated regions: an N-terminal actin-binding domain, a Rho-specific dbl homology (DH)- pleckstrin homology (PH) type GEF domain and a ...
Diogjena Katerina Prifti +2 more
doaj +1 more source
Advanced Materials, EarlyView.This work offers unique Ginger‐based 3D‐printable resins that can print customizable high‐resolution complex designs. The customizable printing backbone of Zingerol prints also mimics various human bones' strength. Acquisition of in‐vivo biocompatibility in rat model with no severe inflammatory response, along with in‐vitro antioxidant and ex‐vivo anti‐
Simran Jindal +9 more
wiley +1 more source
Biocompatible Ink Optimization Enables Functional Volumetric Bioprinting With Xolography
Advanced Materials, EarlyView.Xolography's reliance on weak‐base co‐initiators introduces unique biochemical constraints. By dissecting the effects of extracellular pH, osmolality, and lysosomotropic stress, this study defines the biochemical design space that enables fully biocompatible, cell‐laden volumetric printing. Abstract Xolography is a novel linear volumetric manufacturing
Erik Brauer +17 more
wiley +1 more source
Where, When, and How? Integrating Spatiotemporal Cues in Cell Division. [PDF]
BioessaysAccurate chromosome segregation during mitosis depends on the spatial and temporal regulation of spindle assembly, kinetochore‐microtubule attachment, and checkpoint signaling. Here, we highlight how mitotic chromosomes can serve as dynamic hubs that integrate molecular cues to coordinate spindle organization and timing, ensuring faithful genome ...
Cirillo L +3 more
europepmc +2 more sources