PEBP1/RKIP: from multiple functions to a common role in cellular processes [PDF]
PEBPs (PhosphatidylEthanolamine Binding Proteins) form a protein family widely present in the living world since they are encountered in microorganisms, plants and animals. In all organisms PEBPs appear to regulate important mechanisms that govern cell cycle, proliferation, differentiation and motility.
arxiv
Thymoquinone disrupts the microtubule dynamics in fission yeast Schizosaccharomyces pombe
Mad2 deletion strain of Schizosaccharomyces pombe was found to be sensitive to thymoquinone, a signature molecule present in Nigella sativa in a dose-dependent manner.
Nusrat Masood+3 more
doaj +1 more source
In this paper, spindle starshaped sets are introduced and investigated, which apart from normalization form an everywhere dense subfamily within the family of starshaped sets. We focus on proving spindle starshaped analogues of recent theorems of Bobylev, Breen, Toranzos, and Zamfirescu on starshaped sets.
arxiv
Optimal Multi-Level Interval-based Checkpointing for Exascale Stream Processing Systems [PDF]
State-of-the-art stream processing platforms make use of checkpointing to support fault tolerance, where a "checkpoint tuple" flows through the topology to all operators, indicating a checkpoint and triggering a checkpoint operation. The checkpoint will enable recovering from any kind of failure, be it as localized as a process fault or as wide spread ...
arxiv
Measuring and modeling polymer gradients argues that spindle microtubules regulate their own nucleation [PDF]
Spindles are self-organized microtubule-based structures that segregate chromosomes during cell division. The mass of the spindle is controlled by the balance between microtubule turnover and nucleation. The mechanisms that control the spatial regulation of microtubule nucleation remain poorly understood.
arxiv +1 more source
Gap junction plasticity can lead to spindle oscillations [PDF]
Patterns of waxing and waning oscillations, called spindles, are observed in multiple brain regions during sleep. Spindle are thought to be involved in memory consolidation. The origin of spindle oscillations is ongoing work but experimental results point towards the thalamic reticular nucleus (TRN) as a likely candidate.
arxiv
Rapidly Progressing Renal Cell Carcinoma With Unexpected Inferior Vena Cava Tumor Thrombus
ABSTRACT Introduction We report here a case of RCC without preoperative tumor thrombus that had progressed to RCC with IVC tumor thrombus. Case Presentation A 75‐year‐old man was referred to our hospital. Contrast‐enhanced CT showed a 50‐mm mass in the right kidney with an indistinct border, contrast in the early phase and washout in the late phase ...
Sohei Iwagami+5 more
wiley +1 more source
The Spindle Assembly Checkpoint: Clock or Domino?
In each cell division, the newly duplicated chromosomes must be evenly distributed between the sister cells. Errors in this process during meiosis or mitosis are equally fatal: improper segregation of the chromosome 21 during human meiosis leads to Down syndrome (Conley, Aneuploidy: etiology and mechanisms, pp 35-89, 1985), whereas in somatic cells ...
de Medina-Redondo Maria, Meraldi Patrick
openaire +4 more sources
Nanomaterials for acute myeloid leukemia therapy: Current progress and future perspectives
Infographics of this review introducing the current treatment strategies, types of nanomaterials, and their advantages in AML treatment (Created with BioRender.com, a license purchased, accessed on March 26, 2024). Abstract Acute myeloid leukemia (AML) is a highly aggressive hematologic malignancy characterized by poor prognosis, high relapse rates ...
Jiarui Zhao+8 more
wiley +1 more source
MAP kinase meets mitosis: A role for Raf Kinase Inhibitory Protein in spindle checkpoint regulation
Raf Kinase Inhibitory Protein (RKIP) is an evolutionarily conserved protein that functions as a modulator of signaling by the MAP kinase cascade.
Rosner Marsha
doaj +1 more source