Identification of Saccharomyces cerevisiae spindle pole body remodeling factors. [PDF]
PLoS ONE, 2010 The Saccharomyces cerevisiae centrosome or spindle pole body (SPB) is a dynamic structure that is remodeled in a cell cycle dependent manner. The SPB increases in size late in the cell cycle and during most cell cycle arrests and exchanges components ...
Kristen B Greenland +4 more
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Novel phosphorylation states of the yeast spindle pole body [PDF]
Biology Open, 2018 Phosphorylation regulates yeast spindle pole body (SPB) duplication and separation and likely regulates microtubule nucleation. We report a phosphoproteomic analysis using tandem mass spectrometry of enriched Saccharomyces cerevisiae SPBs for two cell ...
Kimberly K. Fong +7 more
doaj +6 more sources
Analysis of the protein composition of the spindle pole body during sporulation in Ashbya gossypii. [PDF]
PLoS ONE, 2019 The spores of fungi come in a wide variety of forms and sizes, highly adapted to the route of dispersal and to survival under specific environmental conditions.
Dario Wabner +5 more
doaj +4 more sources
Phosphosites of the yeast centrosome component Spc110 contribute to cell cycle progression and mitotic exit [PDF]
Biology Open, 2022 The microtubule organizing center (MTOC) is a specialized structure with a main function in microtubule (MT) nucleation and organization. In higher eukaryotes, the main MTOC is known as the centrosome, and its functional equivalent in yeast is the ...
Marjan Abbasi +5 more
doaj +3 more sources
Role of spindle pole body component 25 in neurodegeneration [PDF]
Annals of Translational Medicine, 2021 Aberrant growth and polarization of microglia are critical for pathological initiation and progression of neurodegenerative conditions like Alzheimer's disease (AD). However, the molecular signals that govern the outgrowth of microglia have not yet been fully determined.
Jianpeng Hu +3 more
openaire +4 more sources
Astral microtubule pivoting promotes their search for cortical anchor sites during mitosis in budding yeast. [PDF]
PLoS ONE, 2014 Positioning of the mitotic spindle is crucial for proper cell division. In the budding yeast Saccharomyces cerevisiae, two mechanisms contribute to spindle positioning.
Stephan Baumgärtner, Iva M Tolić
doaj +4 more sources
Disjunction of conjoined twins: Cdk1, Cdh1 and separation of centrosomes [PDF]
Cell Division, 2006 Accurate transmission of chromosomes from parent to progeny cell requires assembly of a bipolar spindle. Centrosomes (spindle pole body in yeast) are critical for the biogenesis of this complex mitotic apparatus since they confer bipolarity on the ...
Surana Uttam, Crasta Karen
doaj +4 more sources
Microtubule Nucleation at Non-Spindle Pole Body Microtubule-Organizing Centers Requires Fission Yeast Centrosomin-Related Protein mod20p [PDF]
, 2004 Background: Many types of differentiated eukaryotic cells display microtubule distributions consistent with nucleation from noncentrosomal intracellular microtubule organizing centers (MTOCs), although such structures remain poorly characterized.
Lourenco, Paula C.C +2 more
core +3 more sources
Centriole assembly and the role of Mps1: defensible or dispensable? [PDF]
Cell Division, 2011 The Mps1 protein kinase is an intriguing and controversial player in centriole assembly. Originally shown to control duplication of the budding yeast spindle pole body, Mps1 is present in eukaryotes from yeast to humans, the nematode C.
Fisk Harold A, Pike Amanda N
doaj +5 more sources
Csi1p recruits alp7p/TACC to the spindle pole bodies for bipolar spindle formation [PDF]
Molecular Biology of the Cell, 2014 Student Oral Presentation Session 2Accurate chromosome segregation requires timely bipolar spindle formation during mitosis. The transforming acidic coiled-coil (TACC) family proteins and the ch-TOG family proteins are key players in bipolar spindle ...
Fu, C, Zheng, F
core +5 more sources