Results 111 to 120 of about 110,511 (285)
Accurate chromosome segregation by probabilistic self-organization [PDF]
BMC Biology 2015 13:65, 2014 Background: For faithful chromosome segregation during cell division, correct attachments must be established between sister chromosomes and microtubules from opposite spindle poles through kinetochores (chromosome bi-orientation). Incorrect attachments of kinetochore microtubules (kMTs) lead to chromosome mis-segregation and aneuploidy, which is often
arxiv +1 more source
Developmental Dynamics, EarlyView.Abstract Background The avian node is the equivalent of the amphibian Spemann's organizer, as indicated by its ability to induce a secondary axis, cellular contribution, and gene expression, whereas the node of the mouse, which displays limited inductive capacities, was suggested to be a part of spatially distributed signaling.
Braah Harmoush +2 more
wiley +1 more source
Defect driven shapes in nematic droplets: analogies with cell division [PDF]
Soft Matter 13, 1257 (2017), 2016 Building on the striking similarity between the structure of the spindle during mitosis in living cells and nematic textures in confined liquid crystals, we use a continuum model of two-dimensional nematic liquid crystal droplets, to examine the physical aspects of cell division.
arxiv +1 more source
Lte1 contributes to Bfa1 localization rather than stimulating nucleotide exchange by Tem1 [PDF]
Reevaluation of Lte1’s involvement in the mitotic exit network reveals that it is involved in localizing Bfa1 to the spindle pole body but does not function as a GEF for ...
Adames +66 more
core +2 more sources
The fork head transcription factor Hcm1p participates in the regulation of SPC110, which encodes the calmodulin-binding protein in the yeast spindle pole body [PDF]
, 1998 We previously identified HCM1 as a dosage-dependent suppressor of a calmodulin temperature-sensitive mutant (cmd1-1). Calmodulin performs multiple functions in yeast.
Davis, Trisha N., Zhu, Gefeng
core +1 more source
Tem1 localization to the spindle pole bodies is essential for mitotic exit and impairs spindle checkpoint function [PDF]
Journal of Cell Biology, 2011 The mitotic exit network (MEN) is a signaling cascade that triggers inactivation of the mitotic cyclin-dependent kinases and exit from mitosis. The GTPase Tem1 localizes on the spindle pole bodies (SPBs) and initiates MEN signaling. Tem1 activity is inhibited until anaphase by Bfa1-Bub2.
M. Valerio-Santiago, F. Monje-Casas
openaire +5 more sources
The density of Meissner polyhedra [PDF]
arXiv, 2023 We consider Meissner polyhedra in $\mathbb{R}^3$. These are constant width bodies whose boundaries consist of pieces of spheres and spindle tori. We define these shapes by taking appropriate intersections of congruent balls and show that they are dense within the space of constant width bodies in the Hausdorff topology.
arxiv
, 2016 Anaphase B spindle elongation is characterized by the sliding apart of overlapping antiparallel interpolar (ip) microtubules (MTs) as the two opposite spindle poles separate, pulling along disjoined sister chromatids, thereby contributing to chromosome ...
Brust-Mascher, Ingrid +2 more
core +2 more sources
Nuclear envelope insertion of spindle pole bodies and nuclear pore complexes [PDF]
Nucleus, 2012 The defining feature of eukaryotic cells is the double lipid bilayer of the nuclear envelope (NE) that serves as a physical barrier separating the genome from the cytosol. Nuclear pore complexes (NPCs) are embedded in the NE to facilitate transport of proteins and other macromolecules into and out of the nucleus. In fungi and early embryos where the NE
Sue L. Jaspersen, Suman Ghosh
openaire +3 more sources
Unveil Sleep Spindles with Concentration of Frequency and Time [PDF]
arXiv, 2023 Objective: Sleep spindles contain crucial brain dynamics information. We introduce the novel non-linear time-frequency analysis tool 'Concentration of Frequency and Time' (ConceFT) to create an interpretable automated algorithm for sleep spindle annotation in EEG data and to measure spindle instantaneous frequencies (IFs).
arxiv