Results 181 to 190 of about 37,365 (214)
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Asymmetric mitotic segregation of the yeast spindle pole body
Cell, 1992The yeast KAR1 gene is required for spindle pole body (SPB) duplication and nuclear fusion. We determine here that KAR1-beta-galactosidase hybrid proteins localize to the outer face of the SPB. Remarkably, after SPB duplication, the hybrid protein was found associated with only one of the two SPBs, usually the one that enters the bud.
Tom Roberts +4 more
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Assembly and functions of the spindle pole body in budding yeast
Trends in Genetics, 1993The spindle pole body (SPB) serves as the centrosome in yeasts and in a variety of other lower eukaryotes. In Saccharomyces cerevisiae, this organelle controls the assembly of all microtubules in the cell, acting not only as a pole of the mitotic or meiotic spindle but also as the site from which cytoplasmic microtubules emanate.
Breck Byers, Mark Winey
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Spindle pole body duplication: a model for centrosome duplication?
Trends in Cell Biology, 2000The yeast spindle pole body (SPB) is the functional equivalent of the centrosome and forms the two poles of the mitotic spindle. Before mitosis, both SPBs and centrosomes are present as single copies and must be duplicated to form the bipolar spindle. SPB components have been identified using a combination of biochemistry and genetics, and their role ...
John V. Kilmartin, Ian R. Adams
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Electron Microscopy of Spindle Pole Bodies in Pathogenic Fungi
Nippon Ishinkin Gakkai Zasshi, 2010Morphology and dynamics of the spindle pole bodies (SPBs) in Exophiala dermatitidis and Cryptococcus neoformans were examined by freeze-substitution and serial ultrathin sectioning electron microscopy. The SPBs showed double forms and were located on the nuclear envelope in G1 phase, entered the nuclear membrane or the periphery of nucleus in M phase ...
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THE BUDDING YEAST SPINDLE POLE BODY: Structure, Duplication, and Function
Annual Review of Cell and Developmental Biology, 2004▪ Abstract Nucleation of microtubules by eukaryotic microtubule organizing centers (MTOCs) is required for a variety of functions, including chromosome segregation during mitosis and meiosis, cytokinesis, fertilization, cellular morphogenesis, cell motility, and intracellular trafficking.
Mark Winey, Sue L. Jaspersen
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Meiosis in Coprinus: IV. morphology and behaviour of spindle pole bodies [PDF]
Journal of Cell Science, 1973 ABSTRACT Meiotic synchrony in the genus Coprinus has permitted the sequential study of spindle pole body (SPB) behaviour through the meiotic process. The SPBs are monoglobular in the young basidia immediately after the last premeiotic mitosis. From 10 to 15 h before karyogamy until pachytene, spindle pole bodies are not found.
B. C. Lu, N. B. Raju
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Genetic analysis of yeast spindle pole bodies
2001Publisher Summary This chapter discusses the genetic analysis of yeast spindle pole bodies. The chapter explains the concepts and methods for three powerful genetic screens that have been fruitful in yielding spindle pole body (SPB) components: a dosage-dependent suppressor screen, an extragenic suppressor screen, and a synthetic lethal screen.
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Mini review: Mitosis and the spindle pole body inSaccharomyces cerevisiae
The Journal of Experimental Zoology, 1997Cell duplication is characteristic of life. The coordination of cell growth with cell duplication and, specifically, the ordered steps necessary for this process are termed the cell cycle. Central to this process is the faithful replication and segregation of the chromosomes.
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Biochemical and Biophysical Research Communications - BBRC, 2018
Jangho Jeong +8 more
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Jangho Jeong +8 more
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