Results 21 to 30 of about 37,365 (214)
Sfi1p has conserved centrin-binding sites and an essential function in budding yeast spindle pole body duplication [PDF]
Journal of Cell Biology, 2003 Centrins are calmodulin-like proteins present in microtubule-organizing centers. The Saccharomyces cerevisiae centrin, Cdc31p, was functionally tagged with a single Z domain of protein A, and used in pull-down experiments to isolate Cdc31p-binding ...
John V. Kilmartin
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Analysis of the protein composition of the spindle pole body during sporulation in Ashbya gossypii. [PDF]
PLoS One, 2019 Wabner D +5 more
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Disappearance of Cdc14 from the daughter spindle pole body requires Glc7-Bud14. [PDF]
Turk J BiolKirdök İ, Çaydaşi AK.
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The KASH protein Kms2 coordinates mitotic remodeling of the spindle pole body.
J Cell Sci, 2014 Wälde S, King MC.
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Bud14 function is crucial for spindle pole body size maintenance. [PDF]
Turk J BiolSpindle pole bodies (SPB), the functional equivalent of centrosomes in yeast, duplicate through generation of a new SPB next to the old one. However, SPBs are dynamic structures that can grow and exchange, and mechanisms that regulate SPB size remain largely unknown.
Girgin SM, Çaydaşi AK.
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Current Biology, 2013 What is a spindle pole body? The spindle pole body (SPB) or duplication plaque of fungi is the functional equivalent of the centrosome in higher eukaryotes. SPBs serve as microtubule organizing centres (MTOCs), sites where microtubules (MTs) are assembled from tubulin subunits. In contrast to centrosomes, SPBs do not contain centrioles.
Christian Seybold, Elmar Schiebel
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Components of the yeast spindle and spindle pole body. [PDF]
The Journal of cell biology, 1990 Yeast spindle pole bodies (SPBs) with attached nuclear microtubles were enriched approximately 600-fold from yeast cell extracts. 14 mAbs prepared against this enriched SPB fraction define at least three components of the SPB and spindle. Immunofluorescent staining of yeast cells showed that throughout the cell cycle two of the components (110 and 90 ...
Michael P. Rout, John V. Kilmartin
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Regulation of cytokinesis by spindle-pole bodies [PDF]
Nature Cell Biology, 2006 In the fission yeast Schizosaccharomyces pombe, cytokinesis is thought to be controlled by the daughter spindle-pole body (SPB) through a regulatory pathway named the septation initiation network (SIN). Here, we demonstrate that laser ablation of both, but not a single SPB, results in failure of cytokinesis.
Valentin Magidson +4 more
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The core spindle pole body scaffold Ppc89 links the pericentrin orthologue Pcp1 to the fission yeast spindle pole body via an evolutionarily conserved interface. [PDF]
Mol Biol CellCentrosomes and spindle pole bodies (SPBs) are important for mitotic spindle formation and serve as cellular signaling platforms. Although centrosomes and SPBs differ in morphology, many mechanistic insights into centrosome function have been gleaned from SPB studies.
Chen JS +8 more
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