Results 21 to 30 of about 110,511 (285)
Duplication of the Yeast Spindle Pole Body Once per Cell Cycle [PDF]
Molecular and Cellular Biology, 2016 The yeast spindle pole body (SPB) is the functional equivalent of the mammalian centrosome. Centrosomes and SPBs duplicate exactly once per cell cycle by mechanisms that use the mother structure as a platform for the assembly of the daughter. The conserved Sfi1 and centrin proteins are essential components of the SPB duplication process.
Elmar Schiebel, Diana Rüthnick
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The Mitotic Exit Network Regulates Spindle Pole Body Selection During Sporulation of Saccharomyces cerevisiae [PDF]
Genetics, 2017 Christian Renicke +4 more
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The molecular architecture of the yeast spindle pole body core determined by Bayesian integrative modeling [PDF]
Mol Biol Cell, 2017 Shruthi Viswanath +16 more
europepmc +5 more sources
Sec66-Dependent Regulation of Yeast Spindle-Pole Body Duplication Through Pom152 [PDF]
Genetics, 2015 Santharam S. Katta +8 more
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Current Biology, 2013 What is a spindle pole body? The spindle pole body (SPB) or duplication plaque of fungi is the functional equivalent of the centrosome in higher eukaryotes. SPBs serve as microtubule organizing centres (MTOCs), sites where microtubules (MTs) are assembled from tubulin subunits. In contrast to centrosomes, SPBs do not contain centrioles.
Christian Seybold, Elmar Schiebel
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Fission yeast cells undergo nuclear division in the absence of spindle microtubules. [PDF]
PLoS Biology, 2010 Mitosis in eukaryotic cells employs spindle microtubules to drive accurate chromosome segregation at cell division. Cells lacking spindle microtubules arrest in mitosis due to a spindle checkpoint that delays mitotic progression until all chromosomes ...
Stefania Castagnetti +2 more
doaj +1 more source
Components of the yeast spindle and spindle pole body. [PDF]
The Journal of cell biology, 1990 Yeast spindle pole bodies (SPBs) with attached nuclear microtubles were enriched approximately 600-fold from yeast cell extracts. 14 mAbs prepared against this enriched SPB fraction define at least three components of the SPB and spindle. Immunofluorescent staining of yeast cells showed that throughout the cell cycle two of the components (110 and 90 ...
Michael P. Rout, John V. Kilmartin
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Yeast Kinesin-5 Motor Protein CIN8 Promotes Accurate Chromosome Segregation
Cells, 2022 Accurate chromosome segregation depends on bipolar chromosome–microtubule attachment and tension generation on chromosomes. Incorrect chromosome attachment results in chromosome missegregation, which contributes to genome instability.
Delaney Sherwin +2 more
doaj +1 more source
Regulation of cytokinesis by spindle-pole bodies [PDF]
Nature Cell Biology, 2006 In the fission yeast Schizosaccharomyces pombe, cytokinesis is thought to be controlled by the daughter spindle-pole body (SPB) through a regulatory pathway named the septation initiation network (SIN). Here, we demonstrate that laser ablation of both, but not a single SPB, results in failure of cytokinesis.
Valentin Magidson +4 more
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Environmental and Molecular Mutagenesis, Volume 63, Issue 8-9, Page 389-399, December 2022., 2022 Abstract Black cohosh (BC; Actaea racemosa L.), a top‐selling botanical dietary supplement, is marketed to women primarily to ameliorate a variety of gynecological symptoms. Due to widespread usage, limited safety information, and sporadic reports of hepatotoxicity, the Division of the National Toxicology Program (DNTP) initially evaluated BC extract ...
Stephanie L. Smith‐Roe +15 more
wiley +1 more source