Results 31 to 40 of about 110,511 (285)
Hepatology, EarlyView., 2022 Hepatic endothelial Alk1 signaling protects from development of vascular malformations while maintaining organ‐specific endothelial differentiation and angiocrine portmanteau of the names Wingless and Int‐1 signaling. Abstract Background and Aims In hereditary hemorrhagic telangiectasia (HHT), severe liver vascular malformations are associated with ...
Christian David Schmid +20 more
wiley +1 more source
Cosegregation of asymmetric features during cell division
Open Biology, 2021 Cellular asymmetry plays a major role in the ageing and evolution of multicellular organisms. However, it remains unknown how the cell distinguishes ‘old’ from ‘new’ and whether asymmetry is an attribute of highly specialized cells or a feature inherent ...
Silje Anda +3 more
doaj +1 more source
Metabolite profiling of human‐originated Lachnospiraceae at the strain level
iMeta, Volume 1, Issue 4, December 2022., 2022 The human‐originated Lachnospiraceae biobank included 77 species was constructed. In vitro metabolite profiling of 110 Lachnospiraceae strains yielded 242 metabolites of 17 categories. Many Lachnospiraceae strains produce short‐chain fatty acids, and Agathobacter rectalis strain Lach‐101 and Coprococcus comes strain NSJ‐173 are the top two butyric acid
Rashidin Abdugheni +11 more
wiley +1 more source
Cells, 2022 The spindle position checkpoint (SPOC) of budding yeast delays mitotic exit in response to misaligned spindles to ensure cell survival and the maintenance of genomic stability.
Yan Li, Kiwon Song
doaj +1 more source
Coordination of chromatid separation and spindle elongation by antagonistic activities of mitotic and S-phase CDKs. [PDF]
PLoS Genetics, 2013 Because cohesion prevents sister-chromatid separation and spindle elongation, cohesion dissolution may trigger these two events simultaneously. However, the relatively normal spindle elongation kinetics in yeast cohesin mutants indicates an additional ...
Fengshan Liang +2 more
doaj +1 more source
Rotating multi-charge spindles and their microstates [PDF]
JHEP07(2021)182, 2021 Some AdS$_3 \times M_7$ type IIB vacua have been recently proposed to arise from D3-branes wrapped on a spindle, a sphere with conical singularities at the poles. We explicitly construct a generalization of these solutions corresponding to a class of electrically charged and rotating supersymmetric black strings in AdS$_5 \times S^5$ with general ...
arxiv +1 more source
Measuring Affinities of Fission Yeast Spindle Pole Body Proteins in Live Cells across the Cell Cycle [PDF]
Biophys J, 2013 Chad D. McCormick +3 more
openalex +2 more sources
Knockdown of spindle pole body component 25 homolog inhibits cell proliferation and cycle progression in prostate cancer [PDF]
Oncol Lett, 2018 Feilun Cui +4 more
openalex +3 more sources
Examining the assembly pathways and active microtubule mechanics underlying spindle self-organization [PDF]
Proc. Natl. Acad. Sci. USA 119, e2209053119 (2022), 2020 The bipolar organization of the microtubule-based mitotic spindle is essential for the faithful segregation of chromosomes in cell division. Despite our extensive knowledge of genes and proteins, the physical mechanism of how the ensemble of microtubules can assemble into a proper bipolar shape remains elusive.
arxiv +1 more source
Black holes with spindles at the horizon [PDF]
JHEP 06 (2022) 145, 2021 We construct $AdS_4 \times \Sigma$ and $AdS_2 \times \Sigma \times \Sigma_g$ solutions in F(4) gauged supergravity in six dimensions, where $\Sigma$ is a two dimensional manifold of non-constant curvature with conical singularities at its two poles, called a spindle, and $\Sigma_g$ is a constant curvature Riemann surface of genus g.
arxiv +1 more source