Results 31 to 40 of about 31,479 (277)
Exotic mitotic mechanisms [PDF]
, 2012 The emergence of eukaryotes around two billion years ago provided new challenges for the chromosome segregation machineries: the physical separation of multiple large and linear chromosomes from the microtubule-organizing centres by the nuclear envelope.
Drechsler, Hauke, McAinsh, Andrew D.
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Spindle Alignment Regulates the Dynamic Association of Checkpoint Proteins with Yeast Spindle Pole Bodies [PDF]
Developmental Cell, 2009 In many polarized cells, the accuracy of chromosome segregation depends on the correct positioning of the mitotic spindle. In budding yeast, the spindle positioning checkpoint (SPOC) delays mitotic exit when the anaphase spindle fails to extend toward the mother-daughter axis.
Ayşe Koca Çaydaşı, Gislene Pereira
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, 2016 Anaphase B spindle elongation is characterized by the sliding apart of overlapping antiparallel interpolar (ip) microtubules (MTs) as the two opposite spindle poles separate, pulling along disjoined sister chromatids, thereby contributing to chromosome ...
Brust-Mascher, Ingrid +2 more
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Meiotic Nuclear Oscillations Are Necessary to Avoid Excessive Chromosome Associations
Cell Reports, 2016 Pairing of homologous chromosomes is a crucial step in meiosis, which in fission yeast depends on nuclear oscillations. However, how nuclear oscillations help pairing is unknown.
Mariola R. Chacón +2 more
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Membrane assembly modulates the stability of the meiotic spindle-pole body [PDF]
Journal of Cell Science, 2010 Spore formation in Saccharomyces cerevisiae is driven by de novo assembly of new membranes termed prospore membranes. A vesicle-docking complex called the meiosis II outer plaque (MOP) forms on the cytoplasmic faces of the spindle-pole bodies at the onset of meiosis II and serves as the initiation site for membrane formation.
Erin M. Mathieson +2 more
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HIM-10 is required for kinetochore structure and function on Caenorhabditis elegans holocentric chromosomes. [PDF]
, 2001 Macromolecular structures called kinetochores attach and move chromosomes within the spindle during chromosome segregation. Using electron microscopy, we identified a structure on the holocentric mitotic and meiotic chromosomes of Caenorhabditis elegans ...
Albertson +33 more
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Synthetic Physical Interactions with the Yeast Centrosome
G3: Genes, Genomes, Genetics, 2019 The yeast centrosome or Spindle Pole Body (SPB) is an organelle situated in the nuclear membrane, where it nucleates spindle microtubules and acts as a signaling hub.
Rowan S. M. Howell +2 more
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Interaction of CK1δ with γTuSC ensures proper microtubule assembly and spindle positioning. [PDF]
, 2015 Casein kinase 1δ (CK1δ) family members associate with microtubule-organizing centers (MTOCs) from yeast to humans, but their mitotic roles and targets have yet to be identified.
Agard, David A +10 more
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eLife, 2020 Asymmetric astral microtubule organization drives the polarized orientation of the S. cerevisiae mitotic spindle and primes the invariant inheritance of the old spindle pole body (SPB, the yeast centrosome) by the bud.
Marco Geymonat +6 more
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Perturbing Microtubule Integrity Blocks AMP-Activated Protein Kinase-Induced Meiotic Resumption in Cultured Mouse Oocytes [PDF]
, 2012 The oocyte meiotic spindle is comprised of microtubules (MT) that bind chromatin and regulate both metaphase plate formation and karyokinesis during meiotic maturation; however, little information is known about their role in meiosis reinitiation.
Downs, Stephen, Ya, Ru
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