Results 31 to 40 of about 37,365 (214)

Measuring affinities of fission yeast spindle pole body proteins in live cells across the cell cycle. [PDF]

Biophys J, 2013
McCormick CD, Akamatsu MS, Ti SC, Pollard TD.   +3 more
europepmc   +3 more sources

ALK1 controls hepatic vessel formation, angiodiversity, and angiocrine functions in hereditary hemorrhagic telangiectasia of the liver

Hepatology, EarlyView., 2022
Hepatic endothelial Alk1 signaling protects from development of vascular malformations while maintaining organ‐specific endothelial differentiation and angiocrine portmanteau of the names Wingless and Int‐1 signaling. Abstract Background and Aims In hereditary hemorrhagic telangiectasia (HHT), severe liver vascular malformations are associated with ...
Christian David Schmid, Victor Olsavszky, Manuel Reinhart, Vanessa Weyer, Felix A. Trogisch, Carsten Sticht, Manuel Winkler, Sina W. Kürschner, Johannes Hoffmann, Roxana Ola, Theresa Staniczek, Joerg Heineke, Beate K. Straub, Jens Mittler, Kai Schledzewski, Peter ten Dijke, Karsten Richter, Steven Dooley, Cyrill Géraud, Sergij Goerdt, Philipp‐Sebastian Koch   +20 more
wiley   +1 more source

Direct interaction between yeast spindle pole body components: Kar1p is required for Cdc31p localization to the spindle pole body. [PDF]

The Journal of cell biology, 1994
The Saccharomyces cerevisiae genes KAR1 and CDC31 are required for the initial stages of spindle pole body (SPB) duplication in yeast. The Cdc31 protein is most related to caltractin/centrin, a calcium-binding protein present in microtubule organizing centers in many organisms. Because of a variety of genetic interactions between CDC31 and KAR1 (Vallen,
Mark D. Rose, Sue Biggins
openaire   +2 more sources

The Organization of the Core Proteins of the Yeast Spindle Pole Body [PDF]

Molecular Biology of the Cell, 2005
The spindle pole body (SPB) is the microtubule organizing center of Saccharomyces cerevisiae. Its core includes the proteins Spc42, Spc110 (kendrin/pericentrin ortholog), calmodulin (Cmd1), Spc29, and Cnm67. Each was tagged with CFP and YFP and their proximity to each other was determined by fluorescence resonance energy transfer (FRET).
Brian E. Snydsman, Eileen T. O'Toole, Dale W. Hailey, Daniel R. Gestaut, Bryan A. Sundin, Isabella Novik, Tom H. Giddings, Eric G D Muller, Christine A. Niemann, Trisha N. Davis   +9 more
openaire   +3 more sources

The spindle pole body of Aspergillus nidulans is asymmetrical and contains changing numbers of γ-tubulin complexes

Journal of Cell Science, 2019
Centrosomes are important microtubule-organizing centers (MTOCs) in animal cells. In addition, non-centrosomal MTOCs (ncMTOCs) are found in many cell types. Their composition and structure are only poorly understood.
Xiaolei Gao, Marjorie Schmid, Ying Zhang, Sayumi Fukuda, Norio Takeshita, R. Fischer   +5 more
semanticscholar   +1 more source

TheSaccharomyces cerevisiaeSpindle Pole Body Is a Dynamic Structure [PDF]

Molecular Biology of the Cell, 2003
During spindle pole body (SPB) duplication, the new SPB is assembled at a distinct site adjacent to the old SPB. Using quantitative fluorescence methods, we studied the assembly and dynamics of the core structural SPB component Spc110p. The SPB core exhibits both exchange and growth in a cell cycle-dependent manner.
Kerry Bloom, Tennessee J. Yoder, Trisha N. Davis, Chad G. Pearson   +3 more
openaire   +3 more sources

The spindle pole body component Spc97p interacts with the gamma -tubulin of Saccharomyces cerevisiae and functions in microtubule organization and spindle pole body duplication [PDF]

The EMBO Journal, 1997
Previously, we have shown that the gamma-tubulin Tub4p and the spindle pole body component Spc98p are involved in microtubule organization by the yeast microtubule organizing centre, the spindle pole body (SPB). In this paper we report the identification of SPC97 encoding an essential SPB component that is in association with the SPB substructures that
Knop, M, Pereira, G, Geissler, S, Grein, K, Schiebel, E   +4 more
openaire   +4 more sources

Kinetics of spindle pole body separation in budding yeast. [PDF]

Proceedings of the National Academy of Sciences, 1995
In the budding yeast Saccharomyces cerevisiae, the spindle pole body (SPB) serves as the microtubule-organizing center and is the functional analog of the centrosome of higher organisms. By expressing a fusion of a yeast SPB-associated protein to the Aequorea victoria green fluorescent protein, the movement of the SPBs in living yeast cells undergoing ...
Pamela A. Silver, Jason Kahana, Bruce J. Schnapp   +2 more
openaire   +2 more sources

Warming up at the poles [PDF]

EMBO reports, 2006
The third EMBO workshop on Centrosomes and Spindle Pole Bodies, organized by M. Bornens, S.J. Doxsey, M. Knop and J. Raff, was held at the European Molecular Biology Laboratory in Heidelberg, Germany, between 23 and 27 September 2005. ![][1] This series of meetings (Palazzo, 2002; Stearns & Winey, 1997) began as a joint ASCB/EMBO venture in 1997 ...
Hagan, Iain M., Palazzo, Robert E.
openaire   +2 more sources

Membrane assembly modulates the stability of the meiotic spindle-pole body [PDF]

Journal of Cell Science, 2010
Spore formation in Saccharomyces cerevisiae is driven by de novo assembly of new membranes termed prospore membranes. A vesicle-docking complex called the meiosis II outer plaque (MOP) forms on the cytoplasmic faces of the spindle-pole bodies at the onset of meiosis II and serves as the initiation site for membrane formation.
Erin M Mathieson, C. Schwartz, A. Neiman
semanticscholar   +4 more sources