Results 51 to 60 of about 37,365 (214)

Spindle pole body-anchored Kar3 drives the nucleus along microtubules from another nucleus in preparation for nuclear fusion during yeast karyogamy.

Genes & Development, 2013
Nuclear migration during yeast karyogamy, termed nuclear congression, is required to initiate nuclear fusion. Congression involves a specific regulation of the microtubule minus end-directed kinesin-14 motor Kar3 and a rearrangement of the cytoplasmic ...
Romain Gibeaux, A. Politi, F. Nédélec, C. Antony, M. Knop   +4 more
semanticscholar   +1 more source

Material‐to‐Application Integration: Rapid Fabrication of Field‐Deployable Hydrogel‐SiO2 DNA Separator for Low‐Resource Point‐of‐Care Diagnostics

Advanced Science, EarlyView.
A rapidly fabricated hydrogel‐SiO2 composite enables ultralow‐cost, equipment‐minimized DNA extraction, outperforming commercial kits. Hierarchical microstructures enhance hydrophobic/salt‐bridge‐driven adsorption. Integrated with visual LAMP, this field‐deployable system detects Vibrio parahaemolyticus at 10 CFU mL−1 in <40 min, offering ...
Peipei Li, Xinrong Li, Haojie Wu, Dongmei Yue, Yubo Shang, Shan Gao, Bai Wang, Xiaobin Jiang, Jingwei Jiang, Zunchun Zhou   +9 more
wiley   +1 more source

The Yeast Spindle Pole Body Is Assembled around a Central Crystal of Spc42p [PDF]

Cell, 1997
The spindle pole body (SPB) is the microtubule organizing center (MTOC) in the yeast Saccharomyces that plays a pivotal role in such diverse processes as mitosis, budding, and mating. We have used cryoelectron microscopy and image processing to study the structure of isolated diploid SPBs.
Michael P. Rout, Christopher W. Akey, John V. Kilmartin, Esther Bullitt   +3 more
openaire   +3 more sources

Centimeter‐Scale Self‐Assembling Tendon Organoids Drive Tissue Regeneration

Advanced Science, EarlyView.
Centimeter‐scale tendon organoids are engineered by mimicking the extracellular matrix and optimizing chemical cues to guide tendon stem/progenitor cells. These large, self‐assembling constructs overcome conventional size limitations and exhibit enhanced tenogenic differentiation, extracellular matrix production, and mechanical resilience. Their tissue‐
Tianshun Fang, Hong Zhang, Yuanhao Xie, Xiongfeng Li, Xi Liu, Zichen Wang, Yiwen Xue, Xiaohui Xia, Zetao Wang, Tingyun Lei, Ruifu Lin, Weiliang Shen, Bingbing Wu, Yishan Chen, Yanan Du, Xiao Chen, Zi Yin   +16 more
wiley   +1 more source

An intrinsically disordered yeast prion arrests the cell cycle by sequestering a spindle pole body component

Journal of Cell Biology, 2012
Promiscuous interactions of the intrinsically disordered Rnq1 prion protein with the spindle pole body component Spc42 result in Spc42’s sequestration in insoluble bodies and cell cycle arrest.
S. Treusch, S. Lindquist
semanticscholar   +1 more source

Patient‐Mounted Neuro Optical Coherence Tomography for Targeted Minimally Invasive Micro‐Resolution Volumetric Imaging in Brain In Vivo

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Herein, a patient‐mounted neuro optical coherence tomography system that integrates a 5 degrees‐of‐freedom skull‐mounted robot (Skullbot) with a 0.6 mm neuroendoscope for targeted, minimally invasive deep brain imaging, is developed. The system offers high‐resolution imaging with precise deployment, demonstrated through successful tumor imaging in a ...
Chao Xu, Zhiwei Fang, Huxin Gao, Tinghua Zhang, Tao Zhang, Peng Liu, Hongliang Ren, Wu Yuan   +7 more
wiley   +1 more source

Tem1 localization to the spindle pole bodies is essential for mitotic exit and impairs spindle checkpoint function [PDF]

Journal of Cell Biology, 2011
The mitotic exit network (MEN) is a signaling cascade that triggers inactivation of the mitotic cyclin-dependent kinases and exit from mitosis. The GTPase Tem1 localizes on the spindle pole bodies (SPBs) and initiates MEN signaling. Tem1 activity is inhibited until anaphase by Bfa1-Bub2.
M. Valerio-Santiago, F. Monje-Casas
openaire   +5 more sources

Spindle pole body components are reorganized during fission yeast meiosis

Molecular Biology of the Cell, 2012
We show that spindle pole body (SPB) remodeling during meiosis in fission yeast is essential for meiosis. Many SPB components disappear during meiotic prophase and return to the SPBs at meiosis I onset.
Midori Ohta, Masamitsu Sato, Masayuki Yamamoto   +2 more
semanticscholar   +1 more source

Early synapsids neurosensory diversity revealed by CT and synchrotron scanning

The Anatomical Record, EarlyView.
Abstract Non‐mammaliaform synapsids (NMS) represent the closest relatives of today's mammals among the early amniotes. Exploring their brain and nervous system is key to understanding how mammals evolved. Here, using CT and Synchrotron scanning, we document for the first time three extreme cases of neurosensory and behavioral adaptations that probe ...
J. Benoit, R. Araujo, E. S. Lund, A. Bolton, T. Lafferty, Z. Macungo, V. Fernandez   +6 more
wiley   +1 more source

Constitutive dynein activity in she1 mutants reveals differences in microtubule attachment at the yeast spindle pole body

Molecular Biology of the Cell, 2012
Loss of the dynein inhibitor She1 causes increased rates of microtubule detachment from the yeast spindle pole body. The molecular nature of these detachment events is characterized, and it is shown that their frequency depends on the way in which ...
Zane J. Bergman, Xue Xia, I. Alexandra Amaro, T. Huffaker   +3 more
semanticscholar   +1 more source