Results 81 to 90 of about 31,479 (277)
Mechanisms of spindle positioning. [PDF]
Accurate positioning of spindles is essential for asymmetric mitotic and meiotic cell divisions that are crucial for animal development and oocyte maturation, respectively.
McNally, Francis J
core +1 more source
Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao +4 more
wiley +1 more source
Reliable and robust control of nucleus centering is contingent on nonequilibrium force patterns
Summary: Cell centers their division apparatus to ensure symmetric cell division, a challenging task when the governing dynamics is stochastic. Using fission yeast, we show that the patterning of nonequilibrium polymerization forces of microtubule (MT ...
Ishutesh Jain, Madan Rao, Phong T. Tran
doaj +1 more source
Smc5/6 coordinates formation and resolution of joint molecules with chromosome morphology to ensure meiotic divisions [PDF]
During meiosis, Structural Maintenance of Chromosome (SMC) complexes underpin two fundamental features of meiosis: homologous recombination and chromosome segregation.
A Chavez +115 more
core +3 more sources
CD168 Identifies Proliferating Pancreatic Islet Cells in Murine and Human
This study identifies CD168 as a conserved surface marker for proliferating β‐cells in mouse, human islets, and pancreatic islet tumors. CD168⁺ cells show high proliferation and low insulin expression. CD168+ cells form mostly uni‐β lineage clones, and some of the clones are multi‐lineage.
Shubo Yuan +21 more
wiley +1 more source
The nuclear envelope (NE) contains a specialized set of integral membrane proteins that maintain nuclear shape and integrity and influence chromatin organization and gene expression.
Joseph M. Varberg +5 more
doaj +1 more source
An Extended, Boolean Model of the Septation Initiation Network in S.Pombe Provides Insights into Its Regulation. [PDF]
Cytokinesis in fission yeast is controlled by the Septation Initiation Network (SIN), a protein kinase signaling network using the spindle pole body as scaffold.
Anastasia Chasapi +7 more
doaj +1 more source
Computational identification of transcription factor binding sites by functional analysis of sets of genes sharing overrepresented upstream motifs [PDF]
BACKGROUND: Transcriptional regulation is a key mechanism in the functioning of the cell, and is mostly effected through transcription factors binding to specific recognition motifs located upstream of the coding region of the regulated gene.
Caselle, Michele +4 more
core +4 more sources
Perfluorooctane sulfonate (PFOS) exposure disrupts oocyte maturation and early embryonic development. This study elucidates the mechanism by which enhanced O‐GlcNAcylation of FOXK1 underlies the PFOS‐induced reduction of progesterone levels in granulosa cells and the disturbance of follicular microenvironment.
Shuwen Han +16 more
wiley +1 more source
The proper timing and positioning of cytokinesis/septation is crucial for hyphal growth and conidiation in Aspergillus nidulans. The septation initiation network (SIN) components are a conserved spindle pole body (SPB) localized signaling cascade and the
Ping Jiang, Shujun Zheng, Ling Lu
doaj +1 more source

