Spiro Compound Formation. III. The Formation of Spiro Compounds by the Rearrangement of Bicyclo[5.4.0]-undecene(1,7) and Cyclopentylcyclohexene [PDF]
Bulletin of the Chemical Society of Japan, 1969 Abstract The isomerizations of bicyclo[5.4.0]undecene-(1,7) (IV), spiro[5.5]undecene-1 (V), and 1-cyclopentylcyclohexene (VI) were examined with equivalent amounts of perchloric acid in acetic acid or in ethanol at 75°C. In acetic acid, IV, V, and VI all rearranged to form spiro[5.5]-undecan-1-yl acetate (VII) and spiro[5.5]undecan-2-yl ...
Niichiro Tokura, Masatomo Nojima
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Synthesis and evaluation of novel spiro derivatives for pyrrolopyrimidines as anti-hyperglycemia promising compounds [PDF]
Journal of Enzyme Inhibition and Medicinal Chemistry, 2018 Pyrrolopyrimidin-4-ylidene-malononitriles IIa–d were prepared as important intermediates for preparation of a new series of spiro-pyrrolopyrimidines.
Samar S. Fatahala +3 more
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Advanced Photonics Research, 2022 Spiro compounds are widely used as host matrices in organic light‐emitting diodes (OLEDs). Here, inspired by the recent developments in thermally activated delayed fluorescence (TADF) materials, the potential as a light emitter of two spiro‐configured ...
Pauline Tourneur +8 more
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Chemischer Informationsdienst, 1976 AbstractBei der Behandlung mit Hydrazin erhält man aus den 3‐Phenacyliden‐indolin‐2‐onen (I) die Spirocyclen (III), die zu (IV) acetyliert werden.
Tae Tanaka +2 more
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Synthesis and Crystal Structures of Two Novel O, N-Containing Spiro Compounds
Crystals, 2016 Two novel O, N-containing spiro compounds, C16H16ClNO4 (1) and C16H16N2O6 (2), were prepared by reactions of monosubstituted benzenamine (substituent = –NO2, –Cl) and 1,5-dioxaspiro[5.5]undecane-2,4-dione in ethanol solution of trimethoxymethane.
Wulan Zeng, Jinhe Jiang
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Corrigendum: Exploitation of the Ugi 5-Center-4-Component Reaction (U-5C-4CR) for the Generation of Diverse Libraries of Polycyclic (Spiro)Compounds. [PDF]
Front Chem, 2018 Moni L +5 more
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Spiro-compounds. Part II. Ring Transformation in Spiro-compound from 4-Methylcyclohexanone. A New Synthesis of Cadalene. [PDF]
, 1936 Spiro-compounds. Part II. Ring Transformation in Spiro-compound from 4-Methylcyclohexanone. A New Synthesis of Cadalene.
NRIPENDRA NATH CHATTERJEE
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Chemistry Teacher Trainees’ use of Molecular Models in Learning Spiro and Bicyclic Compounds
Science Education International, 2022 The study diagnosed chemistry teacher trainees’ difficulties in naming and writing structures of spiro and bicyclic compounds. The case study design was conducted in a constructivist environment to enhance chemistry teacher trainees’ ability to construct,
Claudia Quayson +3 more
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New Methods for the Synthesis of Spirocyclic Cephalosporin Analogues
Molecules, 2021 Spiro compounds provide attractive targets in drug discovery due to their inherent three-dimensional structures, which enhance protein interactions, aid solubility and facilitate molecular modelling.
Alan X. Zhao +2 more
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Spiro-Flavonoids in Nature: A Critical Review of Structural Diversity and Bioactivity
Molecules, 2023 Based on the literature data from 1973 to 2022, this work summarizes reports on spiro-flavonoids with a spiro-carbon at the center of their structure and how this affects their isolation methods, stereochemistry, and biological activity.
Łukasz Pecio +3 more
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