Results 191 to 200 of about 3,294 (234)

Ancient gene clusters govern the initiation of monoterpenoid indole alkaloid biosynthesis and C3 stereochemistry inversion. [PDF]

Nat Commun
Hwang J, Kirshner J, Deschênes DAR, Richardson MB, Fleck SJ, Mann SGA, Guo J, Perley JO, Shahsavarani M, Garza-Garcia JJO, Seveck AD, Doiron SS, Mai Z, Silliphant SN, Englehart SA, Blight BA, Calhoun L, Gao D, Lian J, Deslongchamps G, Albert VA, Qu Y.   +21 more
europepmc   +1 more source

Asymmetric Organocatalytic [3 + 2]-Cycloaddition of N‑Alkoxy-4-oxo-acrylamides with Isatin-Derived Ketimines:Access to Enantioselective Synthesis of Spirooxindole-imidazolidinones

Ji Won Han (6806921), Yeongju Kim (16944103), Donggeon Kim (9307178), Dongwook Kim (312119), Sung-Gon Kim (1754293)   +4 more
openalex   +1 more source

Catalyst-controlled regiodivergence and stereodivergence in formal cross-[4+2] cycloadditions: The unique effect of bismuth(III). [PDF]

Sci Adv
Hou Q, Cai C, Liu SJ, Huang W, Peng C, Zhan G, Han B.   +6 more
europepmc   +1 more source

Spirooxindoles as Disruptors of Pre-Formed Fibrils in Neurodegenerative Diseases

Ewan W. Blanch, Anthony Dahdah, Nilamuni H. de Silva, Subashani Maniam   +3 more
openalex   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Enantioselective Construction of Spirooxindole-Fused Cyclopentanes

The Journal of Organic Chemistry, 2021
The present study reports an asymmetric organocatalytic cascade reaction of oxindole derivates with α,β-unsaturated aldehydes efficiently catalyzed by simple chiral secondary amine. Spirooxindole-fused cyclopentanes were produced in excellent isolated yields (up to 98%) with excellent enantiopurities (up to 99% ee) and moderate to high ...
Vojtěch Dočekal, Andrea Vopálenská, Pavel Měrka, Klára Konečná, Ondřej Jand’ourek, Milan Pour, Ivana Císařová, Jan Veselý   +7 more
openaire   +2 more sources

A New Route to Spirooxindoles

Organic Letters, 2000
[reaction: see text]Reaction of indole amides 5 with tributylstannane gave spiroindolenines 9 which are readily converted into spiropyrrolidinyloxindoles. This tricyclic system is found in a number of interesting natural products.
S T, Hilton, T C, Ho, G, Pljevaljcic, K, Jones   +3 more
openaire   +2 more sources

Spirooxindoles as Potential Pharmacophores

Mini-Reviews in Medicinal Chemistry, 2017
The spiroindole heterocyclic scaffold is found in many natural products and has been identified as an important bioactive agent. Over the past few decades, various spiroindole-containing compounds have been reported to possess biological properties and hence found in the structure of many synthetic pharmaceuticals.
Siva S, Panda, Rachel A, Jones, Praveen, Bachawala, Prabhu P, Mohapatra   +3 more
openaire   +3 more sources

Expeditious entry into carbocyclic and heterocyclic spirooxindoles

Organic & Biomolecular Chemistry, 2022
Recent advances in the chemistry of base-, metal-, nano-metal and organo-catalyst mediated achiral and chiral versions of the structurally diverse and pharmaceutically relevant spirooxindoles are gently reviewed.
Madhu Ganesh, Shammy Suraj
openaire   +2 more sources

Spirooxindoles: Promising scaffolds for anticancer agents

European Journal of Medicinal Chemistry, 2015
The search for novel anticancer agents with more selectivity and lower toxicity continues to be an area of intensive investigation. The unique structural features of spirooxindoles together with diverse biological activities have made them privileged structures in new drug discovery.
Bin, Yu, De-Quan, Yu, Hong-Min, Liu
openaire   +2 more sources

Organocatalytic Asymmetric Synthesis of Spirooxindole Embedded Oxazolidines

The Journal of Organic Chemistry, 2021
The first organocatalytic asymmetric synthesis of spirooxindole embedded oxazolidines has been developed via a domino reaction involving hemiaminal formation, followed by an unprecedented aza-Michael reaction between isatin derived N-Boc ketimines and γ-hydroxy enones.
Chandrakanta Parida, Buddhadeb Mondal, Animesh Ghosh, Subhas Chandra Pan   +3 more
openaire   +2 more sources