Results 191 to 200 of about 4,752 (252)

Spirooxindoles: Promising scaffolds for anticancer agents.

ChemInform, 2015
AbstractReview: 84 refs.
Bin Yu, De-Quan Yu, Hong-min Liu
semanticscholar   +5 more sources

Enantioselective Construction of Spirooxindole-Fused Cyclopentanes [PDF]

The Journal of Organic Chemistry, 2021
The present study reports an asymmetric organocatalytic cascade reaction of oxindole derivates with α,β-unsaturated aldehydes efficiently catalyzed by simple chiral secondary amine. Spirooxindole-fused cyclopentanes were produced in excellent isolated yields (up to 98%) with excellent enantiopurities (up to 99% ee) and moderate to high ...
Vojtěch Dočekal, Andrea Vopálenská, Pavel Měrka, Klára Konečná, Ondřej Jand’ourek, Milan Pour, Ivana Císařová, Jan Veselý   +7 more
openaire   +2 more sources

Diastereodivergent Desymmetric Annulation to Access Spirooxindoles: Chemical Probes for Mitosis.

Journal of the American Chemical Society, 2023
Spirooxindoles have emerged as promising architectures for engineering biologically active compounds. The diastereodivergent construction of unique scaffolds of this type with full control of continuous chiral centers including an all-carbon quaternary ...
Yu-Hua Wen, Fengrui Yang, Shuai Li, X. Yao, Jin Song, L. Gong   +5 more
semanticscholar   +1 more source

Photoinduced Synthesis of Functionalized Oxacyclic Spirooxindoles Via Ring Expansion.

Organic Letters, 2023
A versatile photochemical ring-expansion protocol for the synthesis of oxacyclic spirooxindoles under catalyst-free conditions is described. The reaction is enabled by the use of unstrained O-containing heterocycles with 3-diazoindolin-2-ones under ...
D. Qi, J. Bai, Zhuoheng Song, Bin Li, C. Yang, Lin Guo, W. Xia   +6 more
semanticscholar   +1 more source

Recent Advances in Nucleophilic Lewis Base‐Catalyzed Cycloadditions for Synthesis of Spirooxindoles

Advanced Synthesis & Catalysis, 2023
Spirooxindoles are privileged scaffolds in diverse bioactive natural products and pharmaceuticals, significant achievements for the construction of these molecules have thus been made in the past years.
Qing-Feng Li, Jing Ma, Junjia Meng, Erqing Li   +3 more
semanticscholar   +1 more source

Organocatalytic Asymmetric Synthesis of Spirooxindole Embedded Oxazolidines [PDF]

The Journal of Organic Chemistry, 2021
The first organocatalytic asymmetric synthesis of spirooxindole embedded oxazolidines has been developed via a domino reaction involving hemiaminal formation, followed by an unprecedented aza-Michael reaction between isatin derived N-Boc ketimines and γ-hydroxy enones.
Chandrakanta Parida, Buddhadeb Mondal, Animesh Ghosh, Subhas Chandra Pan   +3 more
openaire   +2 more sources

Zinc(II)-Catalyzed [2+2+1] Annulation of Internal Alkenes, Diazooxindoles, and Isocyanates to Access Spirooxindoles.

Organic Letters, 2023
Zinc(II)-catalyzed [2+2+1] annulation of internal alkenes, diazooxindoles, and isocyanates was successfully developed for the construction of multisubstituted spirooxindoles.
Zilong Huang, Jie Lin, Mingrui Li, Yong‐Gui Zhou, Zhengkun Yu   +4 more
semanticscholar   +1 more source

ChemInform Abstract: A New Route to Spirooxindoles.

ChemInform, 2000
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Tim C. T. Ho, Goran Pljevaljcic, Stephen T. Hilton, Keith Jones   +3 more
openaire   +4 more sources

ChemInform Abstract: Strategies for the Enantioselective Synthesis of Spirooxindoles.

ChemInform, 2012
AbstractReview: 85 refs.
Nicolas R. Ball-Jones, Annaliese K. Franz, Joseph J. Badillo   +2 more
openaire   +4 more sources

Recent advances in organocatalytic asymmetric multicomponent cascade reactions for enantioselective synthesis of spirooxindoles

Organic Chemistry Frontiers, 2021
Catalytic asymmetric MCCRs for enantioselective synthesis of spirooxindoles by using chiral phosphoric acids, amines, bifunctional thiourea/squaramides and metal-based reagents as catalysts.
Yongchao Wang, Angel A. Cobo, A. Franz
semanticscholar   +1 more source