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Organocatalytic Approach to Spirooxindoles [PDF]
Paul Richardson, Victor Snieckus
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Selective Synthesis of Spirooxindoles by an Intramolecular Heck–Mizoroki Reaction
Organic Letters, 2017We report a highly diastereoselective synthesis of cyclopentene-spirooxindole derivatives via an intramolecular Heck-Mizoroki reaction using aryl bromides as precursors. The reactions were performed under dry conditions or in a DMF-water system.
Tamal Roy+6 more
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ChemInform Abstract: A General and Efficient Method to Access Tetracyclic Spirooxindole Derivatives.
ChemInform, 2014AbstractAn efficient, simple, and convenient synthetic procedure for the synthesis of tetracyclic spirooxindole derivatives, starting from N‐protected isatins and 2‐fluoropyridine, was successfully developed. It enables the facile formation of a new class of spirooxindoles in which the oxindole core is fused with various heterocycles at the C‐3 ...
Bouakher, Abderrahman El+5 more
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Propagative isatin in organic synthesis of spirooxindoles through catalysis
Tetrahedron, 2023M. Asif+3 more
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Synthesis of novel spirooxindole-pyrrolidines and evaluation of their cytotoxic activity
Pharmacological Reports, 2019A variety of spirooxindoles have demonstrated cytotoxic activity toward several cancer cell lines. This study investigates the cytotoxicity of five novel spirooxindole-pyrrolidines by using the Vero and HeLa cell lines.Vero and HeLa cells were treated with the synthesized spirooxindoles, and the cytotoxicity was evaluated by using the AlamarBlue Cell ...
A. A. Anis’kov+4 more
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Superacid-Promoted synthesis of spirooxindoles
Tetrahedron Letters, 2023Jacob C. Hood+2 more
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Enantioselective Synthesis of Pentacyclic Spirooxindoles [PDF]
Victor Snieckus, Paul Richardson
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Stereoselective Synthesis of Spirooxindoles
Synfacts, 2009Ryo Shintani+4 more
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