Results 181 to 190 of about 17,120 (319)

A mammalian protein of 220 kDa binds pre-mRNAs in the spliceosome: a potential homologue of the yeast PRP8 protein.

, 1990
Mariano A. Garcia‐Blanco, Gregory J. Anderson, Jean D. Beggs, P A Sharp   +3 more
openalex   +1 more source

RNA Epigenetics in Cancer: Current Knowledge and Therapeutic Implications

MedComm, Volume 6, Issue 8, August 2025.
RNA epigenetics regulates cancer through RNA modifications, splicing, transport, and translation. Key components include m⁶A writers, splicing factors, RBPs, and nuclear export machinery. Aberrant RNA metabolism drives tumor progression and immune evasion.
Shanhe Huang, Zonglin Li, Weilong Lin, Ruihui Xie, Hai Huang   +4 more
wiley   +1 more source

LncRNA evf‐2 Exacerbates Podocyte Injury in Diabetic Nephropathy by Inducing Cell Cycle Re‐entry and Inflammation Through Distinct Mechanisms Triggered by hnRNPU

Advanced Science
Albuminuria is a hallmark of diabetic nephropathy (DN). Podocyte injury significantly contributes to proteinuria in DN. Our study found that lncRNA EVF‐2 is upregulated in podocytes of DN patients, correlating with cell cycle re‐entry and inflammation ...
Chaojie Zhang, Hui Zhao, Yufan Yan, Yanfei Li, Min Lei, Yong Liu, Longhua Yang, Huijian Zhao, Sijie Zhou, Shaokang Pan, Zhangsuo Liu, Jia Guo   +11 more
doaj   +1 more source

The RNA helicase Aquarius exhibits structural adaptations mediating its recruitment to spliceosomes

Nature Structural &Molecular Biology, 2015
Inessa De, Sergey Bessonov, Romina V. Hofele, K. D. Santos, C. Will, H. Urlaub, R. Lührmann, V. Pena   +7 more
semanticscholar   +1 more source

Tip110 binding to U6 small nuclear RNA and its participation in pre-mRNA splicing [PDF]

, 2015

core   +1 more source

Prp43 Is an Essential RNA-dependent ATPase Required for Release of Lariat-Intron from the Spliceosome [PDF]

, 2002
Arnold R. Martin, Susanne A. Schneider, Beate Schwer   +2 more
openalex   +1 more source

Proteomic Profiling Informs Mechanisms of Esophageal Adenocarcinoma Inhibition by Cranberry Proanthocyanidins

Molecular Nutrition &Food Research, Volume 69, Issue 15, August 2025.
In this study we utilized proteomic profiling to investigate mechanisms linked to the cancer‐inhibitory effect of cranberry proanthocyanidins (CPACs) on reflux‐induced esophageal adenocarcinoma in a rat model. The results indicate that CPAC inhibits cancer through targeting multiple hallmarks of cancer known to be dysregulated in progression to ...
Yun Zhang, Michelle Lee, Erika de Jesus, Katherine Weh, Connor Howard, Henriette Remmer, Amy B. Howell, Laura A. Kresty   +7 more
wiley   +1 more source

Forks in the tracks: Group II introns, spliceosomes, telomeres and beyond

RNA Biology, 2016
R. Agrawal, Hongwei Wang, M. Belfort
semanticscholar   +1 more source

Impact of Acute Endurance Exercise on Alternative Splicing in Skeletal Muscle

FASEB BioAdvances, Volume 7, Issue 8, August 2025.
Current model on the effects of acute endurance exercise on the AS regulatory mechanism with key trans‐factors/RBPs (e.g., hnRNP‐A1, ‐A3, and TIA1). ABSTRACT Alternative splicing (AS) is a highly conserved posttranscriptional mechanism, generating mRNA variants to diversify the proteome.
Alexander Ahn, Jeongjin J. Kim, Aaron L. Slusher, Jeffrey Y. Ying, Eric Y. Zhang, Andrew T. Ludlow   +5 more
wiley   +1 more source

Recognition of the 5' splice site by the spliceosome.

, 1998
Maria M. Konarska
openalex   +2 more sources