Results 1 to 10 of about 12,587 (144)
Kinetics of mosquito-injected Plasmodium sporozoites in mice: fewer sporozoites are injected into sporozoite-immunized mice. [PDF]
PLoS Pathogens, 2009 Malaria is initiated when the mosquito introduces sporozoites into the skin of a mammalian host. To successfully continue the infection, sporozoites must invade blood vessels in the dermis and be transported to the liver.
Chahnaz Kebaier +2 more
doaj +4 more sources
Translational repression in malaria sporozoites [PDF]
Microbial Cell, 2016 Malaria is a mosquito-borne infectious disease of humans and other animals. It is caused by the parasitic protozoan, Plasmodium. Sporozoites, the infectious form of malaria parasites, are quiescent when they remain in the salivary glands of the Anopheles
Oliver Turque +3 more
doaj +3 more sources
Cryopreservation of Plasmodium Sporozoites
Pathogens, 2022 Malaria is a deadly disease caused by the parasite, Plasmodium, and impacts the lives of millions of people around the world. Following inoculation into mammalian hosts by infected mosquitoes, the sporozoite stage of Plasmodium undergoes obligate ...
Carson Bowers +10 more
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Plasmodium berghei rhoptry neck protein 6 maintains parasite infectivity and virulence [PDF]
mBioApicomplexan parasites possess unique secretory organelles called rhoptries, which are reservoirs for rhoptry neck proteins (RONs) and rhoptry bulb proteins (ROPs) that aid in host cell attachment, invasion, and intracellular proliferation. In Plasmodium
Veeda Narahari +6 more
doaj +2 more sources
Development of whole sporozoite malaria vaccines
Expert Review of Vaccines, 2017 Introduction: Despite recent advances, malaria remains a major health threat both to populations in endemic areas as well travelers, including military personnel, to these areas.
Michael R. Hollingdale, Martha Sedegah
doaj +3 more sources
Veterinary Sciences, 2022 Coccidiosis is one of the most common infectious diseases that causes digestive problems in rabbits, leading to global economic losses. This study was conducted to evaluate the effects of bile obtained from sheep gallbladder on the sporulation and ...
Mutee Murshed +2 more
doaj +1 more source
New Avenues to Design Toxoplasma Vaccines Based on Oocysts and Cysts
Frontiers in Immunology, 2022 Toxoplasmosis is a worldwide disease affecting all warm-blooded animals, including humans. Vaccination strategies aimed at inducing an efficient immune response while preventing transmission have been attempted in the past.
David Arranz-Solís, Jeroen P. J. Saeij
doaj +1 more source
Innate immunity to malaria: The good, the bad and the unknown
Frontiers in Immunology, 2022 Malaria is the cause of 600.000 deaths annually. However, these deaths represent only a tiny fraction of total malaria cases. Repeated natural infections with the causative agent, Plasmodium sp.
Kai Pohl, Kai Pohl, Ian A. Cockburn
doaj +1 more source
Experimental evaluation of cryopreservative solutions to maintain in vitro and in vivo infectivity of P. berghei sporozoites. [PDF]
PLoS ONE, 2017 The rodent malaria parasite Plasmodium berghei is an excellent model organism for laboratory-based experimental evaluation of anti-malarial therapeutics prior to studies with human malaria parasites.
Naresh Singh +3 more
doaj +1 more source
Exit of Plasmodium sporozoites from oocysts is an active process that involves the circumsporozoite protein. [PDF]
PLoS Pathogens, 2005 Plasmodium sporozoites develop within oocysts residing in the mosquito midgut. Mature sporozoites exit the oocysts, enter the hemolymph, and invade the salivary glands.
Qian Wang +2 more
doaj +2 more sources