Results 11 to 20 of about 25,947 (204)
A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity [PDF]
, 2020 Malaria is a global health concern and research efforts are ongoing to develop a superior vaccine to RTS,S/AS01. To guide immunogen design, we seek a comprehensive understanding of the protective humoral response against Plasmodium falciparum ...
Bosch, A. +15 more
core +2 more sources
Traction force generation in Plasmodium sporozoites is modulated by a surface adhesin. [PDF]
J MicroscAbstract Plasmodium sporozoites are the highly polarised and motile forms of the malaria parasite transmitted by mosquitoes to the vertebrate hosts. Sporozoites use myosin motors to generate retrograde flow of actin filaments. These are linked to plasma membrane spanning adhesins, which in turn bind to the extracellular environment, resulting in ...
Ripp J +4 more
europepmc +2 more sources
Insects, 2023 Avian haemosporidians (Apicomplexa, Haemosporida) are widespread blood protists, often causing severe haemosporidiosis, pathology, or even mortality in their hosts.
Rita Žiegytė +2 more
doaj +1 more source
Microorganisms, 2022 Among the alternatives to control avian coccidiosis, alliaceous extracts stand out due to their functional properties. Despite this, most of the references are focused just on garlic.
María Arántzazu Aguinaga-Casañas +5 more
doaj +1 more source
Sporozoite immunization: Innovative Translational Science to Support the Fight against malaria
Expert Review of Vaccines, 2023 Introduction Malaria, a devastating febrile illness caused by protozoan parasites, sickened 247,000,000 people in 2021 and killed 619,000, mostly children and pregnant women in sub-Saharan Africa. A highly effective vaccine is urgently needed, especially
Thomas L. Richie +45 more
doaj +1 more source
Dynamics of Toxoplasma gondii Oocyst Phagocytosis by Macrophages
Frontiers in Cellular and Infection Microbiology, 2020 Oocysts are the environmentally resistant stage of the protozoan parasite Toxoplasma gondii. They are responsible for foodborne infections in humans and animals worldwide.
Omar Ndao +16 more
doaj +1 more source
Specific EtMIC3-binding peptides inhibit Eimeria tenella sporozoites entry into host cells
Veterinary Research, 2021 Avian coccidiosis caused by Eimeria leads to huge economic losses on the global poultry industry. In this study, microneme adhesive repeat regions (MARR) bc1 of E.
Wenjing Chen +6 more
doaj +1 more source
Microstructured blood vessel surrogates reveal structural tropism of motile malaria parasites [PDF]
, 2017 Plasmodium sporozoites, the highly motile forms of the malaria parasite, are transmitted naturally by mosquitoes and traverse the skin to find, associate with, and enter blood capillaries.
Battista, Anna +11 more
core +1 more source
Frontiers in Chemistry, 2020 We have demonstrated previously that amino-artemisinins including artemiside and artemisone in which an amino group replaces the oxygen-bearing substituents attached to C-10 of the current clinical artemisinin derivatives dihydroartemisinin (DHA ...
Ho Ning Wong +12 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2021 Hepatocyte invasion by Plasmodium sporozoites represents a promising target for innovative antimalarial therapy, but the molecular events mediating this process are still largely uncharacterized. We previously showed that Plasmodium falciparum sporozoite
Nadia Amanzougaghene +23 more
doaj +1 more source