Results 31 to 40 of about 25,947 (204)

ATG Ubiquitination Is Required for Circumsporozoite Protein to Subvert Host Innate Immunity Against Rodent Malaria Liver Stage

Frontiers in Immunology, 2022
Although exo-erythrocytic forms (EEFs) of liver stage malaria parasite in the parasitophorous vacuole (PV) are encountered with robust host innate immunity, EEFs can still survive and successfully complete the infection of hepatocytes, and the underlying
Hong Zheng, Hong Zheng, Hong Zheng, Xiao Lu, Xiao Lu, Kai Li, Feng Zhu, Chenhao Zhao, Taiping Liu, Yan Ding, Yong Fu, Kun Zhang, Taoli Zhou, Jigang Dai, Yuzhang Wu, Wenyue Xu, Wenyue Xu   +16 more
doaj   +1 more source

KAI407, a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro. [PDF]

, 2014
Preventing relapses of Plasmodium vivax malaria through a radical cure depends on use of the 8-aminoquinoline primaquine, which is associated with safety and compliance issues.
Borboa, Rachel, Campo, Brice, Chatterjee, Arnab K, Chen, Zhong, Diagana, Thierry T, Gagaring, Kerstin, Glynne, Richard J, Klooster, Els J, Kocken, Clemens HM, Kuhen, Kelli, Leroy, Didier, Luty, Adrian, McNamara, Case W, Nagle, Advait, Plouffe, David M, Remarque, Edmond J, Roland, Jason, Sauerwein, Robert, Thomas, Alan W, van Amsterdam, Sandra M, van den Berg, Alexander, van Gemert, Geert-Jan, Voorberg-van der Wel, Annemarie, Winzeler, Elizabeth A, Yeung, Bryan KS, Zeeman, Anne-Marie   +25 more
core   +1 more source

Antibody and B cell responses to Plasmodium sporozoites [PDF]

, 2014
Antibodies are capable of blocking infection of the liver by Plasmodium sporozoites. Accordingly the induction of anti-sporozoite antibodies is a major aim of various vaccine approaches to malaria.
Cockburn, Ian A., Dups, Johanna N., Pepper, Marion   +2 more
core   +2 more sources

Malaria Diagnosis and the Plasmodium Life Cycle: the BFO Perspective [PDF]

, 2009
Definitive diagnosis of malaria requires the demonstration through laboratory tests of the presence within the patient of malaria parasites or their components.
Barry Smith, Werner Ceusters
core   +3 more sources

Infectivity of Symptomatic Patients and Their Contribution for Infectiousness of Mosquitoes following a Membrane Feeding Assay in Ethiopia

Microbiology Spectrum, 2022
The membrane feeding assay is widely used to evaluate the efficacy of transmission-blocking interventions (TBIs) and identify the reservoir of malaria.
Andargie Abate, Soriya Kedir, Mitiku Bose, Jifar Hassen, Laurent Dembele, Lemu Golassa   +5 more
doaj   +1 more source

Viral proteins expressed in the protozoan parasite Eimeria tenella are detected by the chicken immune system [PDF]

, 2016
BACKGROUND: Eimeria species are parasitic protozoa that cause coccidiosis, an intestinal disease commonly characterised by malabsorption, diarrhoea and haemorrhage that is particularly important in chickens.
Blake, D P, Cockle, C, Crouch, C, Macdonald, S E, Marugan-Hernandez, V, Pegg, E, Tomley, F M   +6 more
core   +3 more sources

Induction and maintenance of protective CD8+ T cells against malaria liver stages: implications for vaccine development

Memorias do Instituto Oswaldo Cruz, 2011
CD8+ T cells against malaria liver stages represent a major protective immune mechanism against infection. Following induction in the peripheral lymph nodes by dendritic cells (DCs), these CD8+ T cells migrate to the liver and eliminate parasite infected
Sze-Wah Tse, Andrea J Radtke, Fidel Zavala   +2 more
doaj   +1 more source

In vitro: Anti-coccidia activity of Calotropis procera leaf extract on Eimeria papillata oocysts sporulation and sporozoite

Open Chemistry, 2022
Natural products play an important role as environmentally friendly agents that can be used against parasitic diseases. Many Eimeria species cause eimeriosis in poultry. The negative effects of synthetic anti-coccidiosis medications necessitate the quest
Murshed Mutee, Al-Quraishy Saleh, Qasem Mahmood A.   +2 more
doaj   +1 more source

Theoretical implications of a pre-erythrocytic Plasmodium vivax vaccine for preventing relapses [PDF]

, 2017
Preventing malaria infection through vaccination requires preventing every sporozoite inoculated by mosquito bite: a major challenge for Plasmodium falciparum.
Amino, R, Mueller, I, White, MT
core   +3 more sources

Shedding of host autophagic proteins from the parasitophorous vacuolar membrane of Plasmodium berghei [PDF]

, 2017
The hepatic stage of the malaria parasite Plasmodium is accompanied by an autophagy-mediated host response directly targeting the parasitophorous vacuolar membrane (PVM) harbouring the parasite.
Agop-Nersesian, Carolina, De Niz, Mariana, Eickel, Nina, Heussler, Volker T., Niklaus, Livia, Prado, Monica   +5 more
core   +2 more sources